KEGG   Homo sapiens (human): 22900
Entry
22900             CDS       T01001                                 
Symbol
CARD8, CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN
Name
(RefSeq) caspase recruitment domain family member 8
  KO
K12801  caspase recruitment domain-containing protein 8
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
Network
nt06521  NLR signaling
  Element
N01568  Regulation of NLRP3 inflammasome signaling pathway, NLRP3 inhibition
Disease
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    22900 (CARD8)
SSDB
Motif
Pfam: FIIND CARD
Other DBs
NCBI-GeneID: 22900
NCBI-ProteinID: NP_001171829
OMIM: 609051
HGNC: 17057
Ensembl: ENSG00000105483
Pharos: Q9Y2G2(Tbio)
UniProt: Q9Y2G2
Structure
Position
19:complement(48179825..48255946)
AA seq 537 aa
MEKKECPEKSSSSEEELPRRDSGSSRNIDASKLIRLQGSRKLLVDNSIRELQYTKTGIFF
QAEACVTNDTVYRELPCVSETLCDISHFFQEDDETEAEPLLFRAVPECQLSGGDIPSVSE
EQESSEGQDSGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRY
SVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAE
PEEAVAEIHLPHFISLQAGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMG
ILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQ
TSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITE
KRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEV
LTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL
NT seq 1614 nt   +upstreamnt  +downstreamnt
atggaaaaaaaggagtgtccagaaaagagtagcagcagtgaggaagagctgccgagacgg
gacagtggatccagtaggaacatagatgcatccaaactcattagactacaaggatcacgg
aaactgttggttgacaatagcatacgggaactgcaatacacaaaaactggaatttttttt
caggctgaggcctgtgtgacaaatgatacggtatacagggagctaccctgtgtttctgag
accctttgtgacatctcacattttttccaagaagatgatgagacagaggcagagccatta
ttgttccgtgctgttcctgagtgtcaactatctgggggggacattcccagtgtatcagaa
gagcaggaatcttcagagggacaagattcaggagacatttgctcagaagagaatcaaata
gtttcctcttatgcttctaaagtctgttttgagatcgaagaagattataaaaatcgtcag
tttctggggcctgaaggaaatgtggatgttgagttgattgataagagcacaaacagatac
agcgtttggttccccactgctggctggtatctgtggtcagccacaggcctcggcttcctg
gtaagggatgaggtcacagtgacgattgcgtttggttcctggagtcagcacctggccctg
gacctgcagcaccatgaacagtggctggtgggcggccccttgtttgatgtcactgcagag
ccagaggaggctgtcgccgaaatccacctcccccacttcatctccctccaagcaggtgag
gtggacgtctcctggtttctcgttgcccattttaagaatgaagggatggtcctggagcat
ccagcccgggtggagcctttctatgctgtcctggaaagccccagcttctctctgatgggc
atcctgctgcggatcgccagtgggactcgcctctccatccccatcacttccaacacattg
atctattatcacccccaccccgaagatattaagttccacttgtaccttgtccccagcgac
gccttgctaacaaaggcgatagatgatgaggaagatcgcttccatggtgtgcgcctgcag
acttcgcccccaatggaacccctgaactttggttccagttatattgtgtctaattctgct
aacctgaaagtaatgcccaaggagttgaaattgtcctacaggagccctggagaaattcag
cacttctcaaaattctatgctgggcagatgaaggaacccattcaacttgagattactgaa
aaaagacatgggactttggtgtgggatactgaggtgaagccagtggatctccagcttgta
gctgcatcagcccctcctcctttctcaggtgcagcctttgtgaaggagaaccaccggcaa
ctccaagccaggatgggggacctgaaaggggtgctcgatgatctccaagacaatgaggtt
cttactgagaatgagaaggagctggtggagcaggaaaagacacggcagagcaagaatgag
gccttgctgagcatggtggagaagaaaggggacctggccctggacgtgctcttcagaagc
attagtgaaagggacccttacctcgtgtcctatcttagacagcagaatttgtaa

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (1)   
   KEGG NETWORK (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (64)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (62)   
DNA sequence (131)   
   RefSeq(nuc) (67)   
   GenBank (32)   
   EMBL (32)   
3D Structure (5)   
   PDB (5)   
Protein domain (2)   
   Pfam (2)   
All databases (222)   

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