KEGG   Homo sapiens (human): 23162
Entry
23162             CDS       T01001                                 
Symbol
MAPK8IP3, JIP-3, JIP3, JSAP1, NEDBA, SYD2, syd
Name
(RefSeq) mitogen-activated protein kinase 8 interacting protein 3
  KO
K04436  mitogen-activated protein kinase 8 interacting protein 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Network
nt06541  Cytoskeleton in neurons
  Element
N01846  Retrograde axonal/dendrite transport, Dynein
Disease
H02862  Neurodevelopmental disorder with or without variable brain abnormalities
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    23162 (MAPK8IP3)
SSDB
Motif
Pfam: WD40_2 JIP_LZII Beta-prop_LRRK2 RH1 ATG14 Beta-prop_IP5PC_F DUF1759
Other DBs
NCBI-GeneID: 23162
NCBI-ProteinID: NP_055948
OMIM: 605431
HGNC: 6884
Ensembl: ENSG00000138834
UniProt: Q9UPT6
Structure
Position
16:1706195..1770351
AA seq 1336 aa
MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVV
NVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKK
ELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIE
RSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKLVPAGDHWHLSDLGQ
LQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGV
GSKNSKRAREKRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLD
RTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEV
GNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELE
EELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKE
RLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRPYPSVNIHY
KSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGR
LQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRP
NEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSRVWILTSTL
TTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGAD
GVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATE
VPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRPEPEPSGDP
TGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGT
LAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKS
FDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKL
GFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARP
GGIIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDS
PAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMSQVKPVLSK
AERSHIIVWQVSYTPE
NT seq 4011 nt   +upstreamnt  +downstreamnt
atgatggagatccagatggacgagggcggcggcgtggtggtgtaccaggacgactactgc
tccggctcggtgatgtcggagcgggtgtcgggcctggcgggctccatctaccgcgagttc
gagcgcctcatccactgctacgacgaggaggtggtcaaggagctcatgccgctggtggtg
aacgtgctggagaacctagactcggtgctcagcgagaaccaggagcacgaggtggagctg
gagctgctgcgcgaggacaacgagcagctgctcacccagtacgagcgtgagaaggcgctg
cgcaggcaggcggaggagaaattcattgagtttgaagatgctctggaacaagagaagaaa
gagctgcaaatccaggtggagcactacgagttccagacgcgccagctggagctgaaggcc
aagaactatgccgatcagatttcccggttggaggagcgggagtcggagatgaagaaggag
tacaatgccctgcaccagcggcacacagagatgatacagacctacgtggagcacattgag
aggtccaagatgcagcaggtcggaggaaacagccagaccgagagcagcctgccggggcgg
aggaaggagcgccccacctccctgaacgtgttccccctggctgacggcacggtacgtgca
cagatcgggggcaagctcgtgcctgcgggggaccactggcacctgagtgacctcggccag
ctgcagtccagctccagctaccagtgtccacaggatgaaatgtccgagtcaggccagtcc
tcggcggccgccacacccagcaccacaggcaccaagtccaacacgcccacatcctccgtg
ccctcggccgccgtcacacccctcaacgagagcctgcagcccctgggggactatggcgtg
ggctccaagaacagcaagcgtgcccgggagaagcgcgacagccgcaacatggaagtacag
gtcacccaggagatgcgcaacgtcagtataggcatgggcagcagtgacgagtggtctgat
gttcaagacattattgactccacgccagagctggacatgtgtccagagacccgcctggac
cgcacaggaagcagcccaacccagggcatcgtgaacaaagctttcggcatcaacaccgac
tccctgtaccatgagctgtcgacggcagggtctgaggtcatcggggatgtggacgaaggg
gccgacctcctaggggagttctcagtgcgcgatgatttctttggaatgggcaaagaagtg
gggaatctgctactggaaaactcacagcttctggaaaccaaaaacgccttgaatgtggtg
aagaatgacctgattgccaaggtcgaccagctgtccggggagcaggaggtgctgaggggc
gagttggaggctgctaagcaggccaaagtcaagctggaaaaccgtatcaaggagctggaa
gaggaactgaaaagagtgaagtccgaggccatcatcgcccgccgtgaacccaaagaagag
gcggaggatgtaagcagctatctctgtacagaatcggacaaaatccccatggcccagcgc
cgccgcttcacgcgggtggagatggcccgtgtgctcatggagcggaaccagtacaaggag
cggctgatggagctgcaggaggctgtgcggtggactgagatgatcagagcgtcccgagag
cacccatccgtccaggagaagaagaagtcgaccatctggcagttcttcagccgcctcttc
agctcttcctccagcccccctccggccaagcgcccctatccctcggtgaacatccactac
aagtcacccaccactgccggcttcagccagcgccgcaaccatgccatgtgcccgatctcg
gcaggcagccggcccctggaattcttccctgacgacgactgcacgtcctccgcccgtcga
gagcagaagcgcgagcagtaccgccaggtgcgtgagcacgtgcgtaacgacgacggccgt
ctgcaggcctgcggctggagcctgcccgccaagtacaagcagctgagtcccaacgggggc
caggaggacacgcggatgaagaacgtgccggtgccggtgtactgccgccctctggtggag
aaggaccccaccatgaagctgtggtgtgccgcgggcgtcaacctgagcgggtggaggccc
aatgaggacgacgctgggaatggagtcaagccagcgccaggccgcgatcccctgacctgc
gaccgcgaaggagacggcgagcccaagagcgcccacacgtctcccgagaagaagaaggcc
aaggagctccctgaaatggacgccacctccagccgggtgtggatcctgaccagcaccctg
accaccagcaaggtggtgatcatcgacgccaaccagccgggcacggtggtggaccagttc
accgtctgcaacgcgcacgtgctgtgcatctccagcatccccgcggccagcgacagcgac
taccctcccggggagatgttcctggacagcgacgtgaacccagaggacccgggcgcagat
ggcgtgctggccggtatcaccctggtgggctgtgccacccgctgcaacgtgccgcggagc
aactgctcctcccgaggggacaccccagtgctagacaaggggcagggggaggtggccacc
atcgccaacgggaaggtcaacccgtcccagtccacagaggaggccacagaggccacggag
gtgccagaccctgggcccagcgagccagagacagccacattgcggcccgggcctctcaca
gagcacgtcttcactgacccagccccgaccccgtcctctggcccccagcctggcagcgag
aacgggccagagcctgacagcagcagcacacggccagagccagagcccagcggggacccc
acgggagcaggcagcagtgctgcacccaccatgtggctgggagcccagaacggctggctc
tatgtgcactcggctgtggccaactggaagaagtgcctgcactccatcaagctgaaggat
tctgtgctgagcctggtgcatgtcaaaggccgtgtgctggtggctctggcggacgggacc
ctggccatcttccaccgtggtgaagatggccagtgggatctgagcaactatcacctaatg
gacctgggccacccgcaccactccatccgctgcatggctgttgtgtacgaccgcgtgtgg
tgtggctacaagaacaaggtgcacgtcatccagcccaagaccatgcagatagagaagtca
tttgacgcccacccgcggcgggagagccaggtgcggcagctggcgtggatcggcgatggc
gtatgggtgtccatccgcctggactccaccctgaggctctaccatgcacacacgcaccag
catctacaggacgtggacattgagccctacgtcagcaagatgctaggcactggcaagctg
ggtttctccttcgtacgcatcacggccctgcttgtcgcgggcagccggctctgggtgggc
accggcaacggagtggtcatctccatccccctgacagagactgtggtcctgcaccgaggc
cagctcctggggctccgagccaataagacatcccccacctctggggagggcgcccgtccc
gggggcatcatccacgtgtatggcgatgacagcagtgacagggcggccagcagcttcatc
ccctactgctccatggcccaggcccagctatgcttccatgggcaccgcgatgccgtgaag
ttctttgtctcggtgccagggaacgtgctggccaccctgaatgggagtgtgctggacagc
ccagccgagggccctgggccagctgcccctgcctcggaggtcgagggccagaagctgcgg
aacgtgctggtgctgagcggcggggagggctacatcgacttccgcattggagacggagag
gacgacgagacggaggagggcgcaggggacatgagccaggtgaagcccgtgctgtccaag
gcagagcgcagtcacatcatcgtgtggcaggtgtcctacacccccgagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (14)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (22)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (66)   
   RefSeq(nuc) (20)   
   GenBank (23)   
   EMBL (23)   
3D Structure (5)   
   PDB (5)   
Protein domain (7)   
   Pfam (7)   
All databases (116)   

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