KEGG   Homo sapiens (human): 23193
Entry
23193             CDS       T01001                                 

Gene name
GANAB, G2AN, GIIA, GLUII, PKD3
Definition
(RefSeq) glucosidase II alpha subunit
  KO
K05546  mannosyl-oligosaccharide alpha-1,3-glucosidase [EC:3.2.1.207]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa01100  Metabolic pathways
hsa04141  Protein processing in endoplasmic reticulum
Module
hsa_M00073  N-glycan precursor trimming
Network
nt06015  N-Glycan biosynthesis
  Element
N00820  N-Glycan biosynthesis
N00821  B4GALT1 deficiency in N-glycan biosynthesis
N00822  MGAT2 deficiency in N-glycan biosynthesis
Disease
H00542  Polycystic kidney disease
H01728  Potter syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    23193 (GANAB)
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    23193 (GANAB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.207  mannosyl-oligosaccharide alpha-1,3-glucosidase
     23193 (GANAB)
SSDB
Motif
Pfam: Glyco_hydro_31 Gal_mutarotas_2 DUF5110
Other DBs
NCBI-GeneID: 23193
NCBI-ProteinID: NP_938148
OMIM: 104160
HGNC: 4138
Ensembl: ENSG00000089597
Vega: OTTHUMG00000167696
Pharos: Q14697(Tchem)
UniProt: Q14697 V9HWJ0
Position
11q12.3
AA seq 944 aa
MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPY
RALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLV
ADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEH
QRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYG
PMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVP
VLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETG
IIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHN
LPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVH
EELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVW
NDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVL
ARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELL
VRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHR
EGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQ
SYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTA
QGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKP
AAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR
NT seq 2835 nt   +upstreamnt  +downstreamnt
atggcggcggtagcggcagtggcggcgcgtaggaggcggtcttgggcgtctttggtactg
gcttttttaggggtctgcctggggattacccttgctgtggatagaagcaactttaagacc
tgtgaagagagttctttctgcaagcgacagagaagcatacggccaggcctctctccatac
cgagccttgctggactctctacagcttggtcctgattccctcacggtccatctgatccat
gaggtcaccaaggtgttgctggtgctagagcttcaggggcttcaaaagaacatgactcgg
ttcaggattgatgagctggagcctcggcgaccccgataccgtgtaccagatgttttggtg
gctgatccaccaatagcccggctttctgtctctggtcgtgatgagaacagtgtggagtta
accatggctgagggaccctacaagatcatcttgacagcacggccattccgccttgaccta
ctagaggaccgaagtcttttgcttagtgtcaatgcccgaggactcttggagtttgagcat
cagagggcccctagggtctcgcaaggatcaaaagacccagctgagggcgatggggcccag
cctgaggaaacacccagggatggcgacaagccagaggagactcaggggaaggcagagaaa
gatgagccaggagcctgggaggagacattcaaaactcactctgacagcaagccgtatggc
cccatgtctgtgggtttggacttctctctgccaggcatggagcatgtctatgggatccct
gagcatgcagacaacctgaggctgaaggtcactgagggtggggagccatatcgcctctac
aatttggatgtgttccagtatgagctgtacaacccaatggccttgtatgggtctgtgcct
gtgctcctggcacacaaccctcatcgcgacttgggcatcttctggctcaatgctgcagag
acctgggttgatatatcttccaacactgccgggaagaccctgtttgggaagatgatggac
tacctgcagggctctggggagaccccacagacagatgttcgctggatgtcagagactggc
atcattgacgtcttcctgctgctggggccctccatctctgatgttttccggcaatatgct
agtctcacaggaacccaggcgttgcccccactcttctccctcggctaccaccagagccgt
tggaactaccgggacgaggctgatgtgctggaagtggatcagggctttgatgatcacaac
ctgccctgtgatgtcatctggctagacattgaacatgctgatggcaagcggtatttcacc
tgggaccccagtcgcttccctcagccccgcaccatgcttgagcgcttggcttctaagagg
cggaagctggtggccatcgtagacccccacatcaaggtggactccggctaccgagttcac
gaggagctgcggaacctggggctgtatgttaaaacccgggatggctctgactatgagggc
tggtgctggccaggctcagctggttaccctgacttcactaatcccacgatgagggcctgg
tgggctaacatgttcagctatgacaattatgagggctcagctcccaacctctttgtctgg
aatgacatgaacgaaccatctgtgttcaatggtcctgaggtcaccatgctcaaggatgcc
cagcattatgggggctgggagcaccgggatgtgcataacatctatggcctttatgtgcac
atggcgactgctgatgggctgagacagcgctctgggggcatggaacgcccctttgtcctg
gccagggccttcttcgctggctcccagcgctttggagccgtgtggacaggggacaacact
gccgagtgggaccatttgaagatctctattcctatgtgtctcagcttggggctggtggga
ctttccttctgtggggcggatgtgggtggcttcttcaaaaacccagagccagagctgctt
gtgcgctggtaccagatgggtgcttaccagccattcttccgggcacatgcccacttggac
actgggcgacgagagccatggctgttaccatctcagcacaatgatataatccgagatgcc
ttgggccagcgatattctttgctgcccttctggtacaccctcttatatcaggcccatcgg
gaaggcattcctgtcatgaggcccctgtgggtgcagtaccctcaggatgtgactaccttc
aatatagatgatcagtacttgcttggggatgcgttgctggttcaccctgtatcagactct
ggagcccatggtgtccaggtctatctgcctggccaaggggaggtgtggtatgacattcaa
agctaccagaagcatcatggtccccagaccctgtacctgcctgtaactctaagcagtatc
cctgtgttccagcgtggagggacaatcgtgcctcgatggatgcgagtgcggcggtcttca
gaatgtatgaaggatgaccccatcactctctttgttgcacttagccctcagggtacagct
caaggagagctctttctggatgatgggcacacgttcaactatcagactcgccaagagttc
ctgctgcgtcgattctcattctctggcaacacccttgtctccagctcagcagaccctgaa
ggacactttgagacaccaatctggattgagcgggtggtgataataggggctggaaagcca
gcagctgtggtactccagacaaaaggatctccagaaagccgcctgtccttccagcatgac
cctgagacctctgtgttggtcctgcgcaagcctggcatcaatgtggcatctgattggagt
attcacctgcgataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (14)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (49)   
   RefSeq(nuc) (11)   
   GenBank (19)   
   EMBL (19)   
Protein domain (3)   
   Pfam (3)   
All databases (115)   

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