KEGG   Homo sapiens (human): 2323
Entry
2323              CDS       T01001                                 

Gene name
FLT3LG, FL, FLG3L, FLT3L
Definition
(RefSeq) fms related receptor tyrosine kinase 3 ligand
  KO
K05454  fms-related tyrosine kinase 3 ligand
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04640  Hematopoietic cell lineage
hsa05200  Pathways in cancer
Network
nt06210  ERK signaling
nt06214  PI3K signaling
nt06219  JAK-STAT signaling
nt06262  Pancreatic cancer
nt06275  Acute myeloid leukemia
  Element
N00217  FLT3LG-FLT3-RAS-ERK signaling pathway
N00218  FLT3LG-FLT3-RAS-PI3K signaling pathway
N00219  FLT3LG-FLT3-STAT5 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    2323 (FLT3LG)
   04014 Ras signaling pathway
    2323 (FLT3LG)
   04151 PI3K-Akt signaling pathway
    2323 (FLT3LG)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    2323 (FLT3LG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2323 (FLT3LG)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    2323 (FLT3LG)
Cytokines and growth factors [BR:hsa04052]
 Growth factors
  Growth factors (RTK binding)
   2323 (FLT3LG)
Motif
Pfam: Flt3_lig
Other DBs
NCBI-GeneID: 2323
NCBI-ProteinID: NP_001191431
OMIM: 600007
HGNC: 3766
Ensembl: ENSG00000090554
Vega: OTTHUMG00000186490
Pharos: P49771(Tbio)
UniProt: P49771 B7ZLY4
Structure
PDB: 
1ETE 3QS7 3QS9

Position
19q13.33
AA seq 235 aa
MTVLAPAWSPTTYLLLLLLLSSGLSGTQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTV
ASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCL
RFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPT
APQPPLLLLLLLPVGLLLLAAAWCLHWQRTRRRTPRPGEQVPPVPSPQDLLLVEH
NT seq 708 nt   +upstreamnt  +downstreamnt
atgacagtgctggcgccagcctggagcccaacaacctatctcctcctgctgctgctgctg
agctcgggactcagtgggacccaggactgctccttccaacacagccccatctcctccgac
ttcgctgtcaaaatccgtgagctgtctgactacctgcttcaagattacccagtcaccgtg
gcctccaacctgcaggacgaggagctctgcgggggcctctggcggctggtcctggcacag
cgctggatggagcggctcaagactgtcgctgggtccaagatgcaaggcttgctggagcgc
gtgaacacggagatacactttgtcaccaaatgtgcctttcagcccccccccagctgtctt
cgcttcgtccagaccaacatctcccgcctcctgcaggagacctccgagcagctggtggcg
ctgaagccctggatcactcgccagaacttctcccggtgcctggagctgcagtgtcagccc
gactcctcaaccctgccacccccatggagtccccggcccctggaggccacagccccgaca
gccccgcagccccctctgctcctcctactgctgctgcccgtgggcctcctgctgctggcc
gctgcctggtgcctgcactggcagaggacgcggcggaggacaccccgccctggggagcag
gtgccccccgtccccagtccccaggacctgctgcttgtggagcactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (23)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (46)   
   RefSeq(nuc) (22)   
   GenBank (12)   
   EMBL (12)   
Protein domain (1)   
   Pfam (1)   
All databases (104)   

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