KEGG   Homo sapiens (human): 23279
Entry
23279             CDS       T01001                                 

Gene name
NUP160, NPHS19
Definition
(RefSeq) nucleoporin 160
  KO
K14303  nuclear pore complex protein Nup160
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  RNA transport
hsa05014  Amyotrophic lateral sclerosis
Network
nt06424  RNA processing
nt06464  Amyotrophic lateral sclerosis
  Element
N01152  Nuclear export of mRNA
N01153  Mutation-caused aberrant GLE1 to nuclear export of mRNA
Disease
H01657  Nephrotic syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    23279 (NUP160)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    23279 (NUP160)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    23279 (NUP160)
   03036 Chromosome and associated proteins [BR:hsa03036]
    23279 (NUP160)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Nuclear pore complex
     23279 (NUP160)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Spindle formation proteins
    23279 (NUP160)
SSDB
Motif
Pfam: Nup160
Other DBs
NCBI-GeneID: 23279
NCBI-ProteinID: NP_056046
OMIM: 607614
HGNC: 18017
Ensembl: ENSG00000030066
Vega: OTTHUMG00000166534
Pharos: Q12769(Tbio)
UniProt: Q12769
Structure
PDB: 
5A9Q

Position
11p11.2
AA seq 1436 aa
MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFR
EFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLD
INLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVD
SQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFV
LKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIF
ALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYM
HAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVK
YINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFC
RGTERNLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQE
ALSHPLALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIA
RDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICS
KLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGV
HKIASTRFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGS
ECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLF
SQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHP
WCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRL
QYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEA
LTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNY
YELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYA
WIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHD
PSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAA
QAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVP
LPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAP
MVWLPYSSIDQLLQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL
NT seq 4311 nt   +upstreamnt  +downstreamnt
atgcttcacctgtccgcagctccgcccgccccacccccggaagtgacggcgaccgcgcgg
ccctgcctttgttccgttgggcgtcgcggcgacggcgggaagatggcggcggcgggagcc
ctggaacggagcttcgtggagctaagcggagctgagcgcgaaaggccgaggcactttcgg
gaattcacagtctgcagcattgggactgcaaatgccgtggctggcgccgtaaaatacagt
gaaagcgcgggaggcttttactacgtggagagtggcaagttgttctccgtaaccagaaac
aggttcattcattggaagacctctggagatacattggagctgatggaggagtcactggac
ataaatctgttgaataatgccattcgcctaaaattccaaaattgcagtgttttacctgga
ggggtttatgtctctgagactcagaatcgtgtgataatcttgatgttaaccaatcaaaca
gtgcacaggttacttttaccacacccctcccggatgtataggagtgagttggtagttgac
agtcagatgcagtcaatattcactgacattggaaaagttgatttcacagatccttgcaac
tatcagttaattccagcagtacctggaatatctcctaattccaccgcctctacagcctgg
ctcagcagtgatggggaggccctgtttgccttaccatgtgcttctgggggaatctttgtt
cttaagctacctccttatgacatacctggtatggtgtcagtcgtggaactgaaacagagt
tcagtaatgcaacgattgcttacaggctggatgccaacagctatcaggggtgaccagtcg
ccttcagatcgtcccctcagtcttgctgttcattgtgtggagcatgatgccttcatcttt
gctttgtgtcaggatcataaactacgaatgtggtcttacaaggagcaaatgtgcctaatg
gtagctgacatgctggagtatgtccctgtgaagaaagaccttcggcttactgctggaact
ggacacaaattacggcttgcttattcccccaccatgggactctacctggggatatacatg
catgcaccaaaacgaggacagttctgcattttccagttggtgagcactgagagtaatcgc
tatagtctcgatcatatttcttcactgttcacttctcaggagacactgattgactttgcc
ttaacttccacggatatctgggccctgtggcatgatgctgagaaccaaacagtagtgaaa
tacatcaactttgaacataatgttgcaggtcagtggaatccagtttttatgcagcctctg
ccagaggaagagattgtcatcagagatgatcaagaccccagagagatgtatctgcaaagt
ctttttacaccaggacaattcacaaatgaagctttatgtaaggctttacagattttctgc
cgaggaactgagaggaatttggatctttcctggagtgaactgaagaaagaagttacttta
gctgttgaaaatgagcttcaaggaagtgtaacagagtatgaattctcccaggaggagttt
cgaaatttacaacaagaattctggtgcaagttctatgcctgttgtcttcagtatcaagaa
gccctctctcaccctcttgccctacatttgaatccacacacaaacatggtgtgcctgctg
aaaaaagggtacctgtctttccttattccctcatccttagtggatcatttgtatctcctg
ccttatgagaaccttttgacagaagatgagacaaccatatctgatgatgtggatatcgct
cgggatgtcatatgtcttataaaatgcctccggctgattgaagagtcagtaactgtggat
atgtcagttataatggaaatgagttgttataacctacagtctccggaaaaggctgcagag
cagattctggaagatatgatcactattgatgtagaaaatgtgatggaggatatttgtagt
aaactgcaagagattaggaacccaatccatgcaattggactacttatacgggaaatggat
tatgaaacagaagtggaaatggaaaagggattcaatccagctcagcctttgaatattcga
atgaatcttacccagctctatggtagtaacacagcagggtatattgtgtgcagaggggtg
cataaaatcgccagtactcgtttcctgatctgcagagatcttttgatcttacagcagctg
ttaatgaggcttggagatgctgtgatttggggaactggtcagctctttcaagctcagcaa
gacctactacatcgaacagctcccctactcttatcttattacctcattaaatggggaagt
gagtgcttggcaactgatgttccacttgacacactggagtctaatctccaacacttatca
gtactggaattaacagactctggtgctttaatggcaaataggtttgtatctagtcctcag
actattgtggagttattcttccaagaagttgcaagaaaacacattatatctcacctcttc
tctcagccaaaggcacctctgagccaaactggattgaattggcctgaaatgattactgca
attaccagttatttattgcagcttttatggcctagcaatcctggttgtctctttctagaa
tgtttgatgggaaattgccaatatgtacaattgcaggattatattcaactgctacatccc
tggtgtcaagtcaatgttggttcctgtcgatttatgctgggaaggtgttacctagttaca
ggagaaggacagaaggctctggaatgtttttgtcaggcagcatctgaagtaggcaaagag
gaattcttggatcgcttgattcgctcagaggatggggagatcgtgtctacccccaggctg
cagtattatgacaaggttttacgactactagatgtcattggtttgcctgaactggttatt
cagttggctacatcagccataactgaagcaggtgatgactggaaaagtcaggctactcta
aggacatgtattttcaaacatcatttggatttgggtcacaatagccaagcatatgaagcc
ttaacccaaattcctgattccagcaggcaattagattgtttacggcagttggtggtagtt
ctttgtgaacgctcacagctacaggatcttgtagagtttccctatgtgaatctgcataat
gaggttgtgggaataattgagtcacgtgctagagctgtggaccttatgactcacaattac
tatgaacttctgtatgcctttcacatctatcgccacaattaccgcaaggctggcacagtg
atgtttgagtatggaatgcggcttggcagagaagttcgaactctccggggacttgagaaa
caaggcaactgttatctggctgctctcaattgtttacgacttattcgtccagaatatgcg
tggattgtgcagccagtgtctggtgcagtgtatgatcgccctggagcatcccctaagagg
aatcatgatggagaatgcacagctgcccccacaaatcgacaaattgaaatcctggaactg
gaagatctggagaaagagtgttccttggctcgcatccgcctcactttggctcagcatgat
ccatcagcggttgcagttgctggaagttcatcagcagaggaaatggtcactctcttggtt
caggcgggcctctttgacactgccatatcactctgtcagacttttaagcttcccttaacg
ccagtctttgaagggcttgccttcaaatgcatcaaattgcaatttggaggagaggcagca
caagcagaagcctgggcctggctagcagccaatcagctctcatctgtcatcactactaag
gagtctagtgctacagatgaagcatggcgactattatccacttacctggagaggtacaaa
gtccagaataacttgtatcaccactgtgtaatcaacaagctcttgtctcatggagtgcct
ctgcctaattggcttataaacagttacaagaaggttgatgctgctgaattgcttcgttta
tacttaaactatgaccttttagaagaagctgtggatttggtgtcagaatatgtggatgct
gtattgggaaaaggacatcaatacttcggaattgagtttccactgtccgcaacagcccca
atggtgtggcttccatactcctctattgatcagcttctccaagctctgggagagaacagt
gccaacagtcacaacatcgcactgtcccagaaaatacttgacaaattggaggactaccag
caaaaagttgataaggcaacacgggatttattatatcgtcggaccttgtga

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