KEGG   Homo sapiens (human): 23304
Entry
23304             CDS       T01001                                 
Symbol
UBR2, C6orf133, bA49A4.1, dJ242G1.1, dJ392M17.3
Name
(RefSeq) ubiquitin protein ligase E3 component n-recognin 2
  KO
K10626  E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    23304 (UBR2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     23304 (UBR2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   UBR box proteins
    23304 (UBR2)
SSDB
Motif
Pfam: PRT6_C UBR1-like_wing zf-UBR ClpS
Other DBs
NCBI-GeneID: 23304
NCBI-ProteinID: NP_056070
OMIM: 609134
HGNC: 21289
Ensembl: ENSG00000024048
UniProt: Q8IWV8 B3KXG6
Structure
Position
6:42564029..42693505
AA seq 1755 aa
MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ
FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
LKYVLISKPTEWSDELRQKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTL
QMKLTHVISMMQDWCASDEKVLIEAYKKCLAVLMQCHGGYTDGEQPITLSICGHSVETIR
YCVSQEKVSIHLPVSRLLAGLHVLLSKSEVAYKFPELLPLSELSPPMLIEHPLRCLVLCA
QVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDVVMLQTGVSMMDPNHFLMIMLSRFEL
YQIFSTPDYGKRFSSEITHKDVVQQNNTLIEEMLYLIIMLVGERFSPGVGQVNATDEIKR
EIIHQLSIKPMAHSELVKSLPEDENKETGMESVIEAVAHFKKPGLTGRGMYELKPECAKE
FNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPVLPPFCPLFASLVNILQSDVMLCI
MGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENVTEEHVVTFTFTQKISKPG
EAPKNSPSILAMLETLQNAPYLEVHKDMIRWILKTFNAVKKMRESSPTSPVAETEGTIME
ESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFIDENKELFQQTLELDASTSAVLDH
SPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQEVKVESRAMVLAAFVQRSTVLSKNR
SKFIQDPEKYDPLFMHPDLSCGTHTSSCGHIMHAHCWQRYFDSVQAKEQRRQQRLRLHTS
YDVENGEFLCPLCECLSNTVIPLLLPPRNIFNNRLNFSDQPNLTQWIRTISQQIKALQFL
RKEESTPNNASTKNSENVDELQLPEGFRPDFRPKIPYSESIKEMLTTFGTATYKVGLKVH
PNEEDPRVPIMCWGSCAYTIQSIERILSDEDKPLFGPLPCRLDDCLRSLTRFAAAHWTVA
SVSVVQGHFCKLFASLVPNDSHEELPCILDIDMFHLLVGLVLAFPALQCQDFSGISLGTG
DLHIFHLVTMAHIIQILLTSCTEENGMDQENPPCEEESAVLALYKTLHQYTGSALKEIPS
GWHLWRSVRAGIMPFLKCSALFFHYLNGVPSPPDIQVPGTSHFEHLCSYLSLPNNLICLF
QENSEIMNSLIESWCRNSEVKRYLEGERDAIRYPRESNKLINLPEDYSSLINQASNFSCP
KSGGDKSRAPTLCLVCGSLLCSQSYCCQTELEGEDVGACTAHTYSCGSGVGIFLRVRECQ
VLFLAGKTKGCFYSPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWHQHSVTEEIGHA
QEANQTLVGIDWQHL
NT seq 5268 nt   +upstreamnt  +downstreamnt
atggcgtcggagctagagccagaggtgcaggccatcgaccggagcttgctggaatgttcg
gccgaggagattgcggggaaatggctgcaagcaactgacctcactagagaagtgtaccag
catttagcccactatgtacccaaaatctactgcaggggtcccaacccttttccacagaaa
gaagacatgctggcacagcatgttttgttgggaccaatggaatggtacctttgtggtgaa
gatcctgcatttggatttccaaaacttgagcaagcaaacaaaccttctcatctttgtggt
cgtgtttttaaagtaggagagcctacatattcttgcagagactgtgcagttgatccaact
tgtgttttgtgcatggagtgctttttgggaagtattcacagagatcatcgatataggatg
acaacatcaggaggtggaggtttctgtgactgtggtgatactgaagcctggaaagagggt
ccttactgtcaaaaacatgaacttaacacctctgaaattgaggaagaagaggatcctctt
gttcatttatcagaagatgtgatagcaagaacttataacatttttgctattacgtttcgg
tatgcagtagaaatattaacctgggaaaaagaaagtgaattgccagcagatttagagatg
gtagagaagagtgacacctactattgcatgctgtttaatgatgaggttcacacctatgaa
caagttatttatactcttcagaaagctgttaactgtacacaaaaagaagctattggtttt
gcaactacagtagatcgagatgggcgtaggtctgttcgatatggagattttcagtattgt
gagcaagcaaaatcagtaattgtgagaaataccagtagacagacaaagccactcaaagtt
caagttatgcattcgtctattgtcgcacatcagaattttggtttgaaacttttgtcttgg
ctgggaagtattattggatattcagatggccttcgccggattttatgtcaagttggttta
caagaagggccagatggtgaaaactcttctctagtggacagactgatgcttagtgattcc
aaattatggaaaggtgctaggagtgtatatcatcagttgttcatgagcagtctgcttatg
gatttgaaatacaagaaactatttgctgttcgatttgcaaaaaattaccagcagttgcag
agagattttatggaggatgatcacgagcgagcagtgtcggtgactgctctatctgtccag
ttcttcaccgcacctactctggctcgaatgctcatcacagaagaaaacttaatgagcatt
atcattaagacttttatggatcatttgagacatcgagatgcccagggcagatttcagttt
gaacgatacactgctttacaagccttcaaatttaggagagtacagagccttattttagat
ctcaagtatgtgttaattagcaaaccaactgaatggtcagatgagctgaggcagaagttc
ctagaagggtttgatgcctttttggaattactaaaatgtatgcagggaatggatccaatt
acacgtcaagtaggacaacatattgaaatggaaccagagtgggaagcagccttcacacta
caaatgaaattaacacatgtcatttcaatgatgcaggactggtgtgcttcagatgaaaaa
gtgttaatcgaagcttacaagaaatgtctcgctgtactgatgcagtgtcatggtggttat
actgatggtgaacagccaatcacactaagcatttgtggacattcagtggaaactatcaga
tactgtgtttcccaagaaaaagttagcattcacctcccagtttctcgcttacttgcaggt
ttacatgtattattaagcaaaagtgaagtggcatataaatttccagagctcctacctcta
agtgaacttagcccacccatgttgatagaacaccctcttagatgtcttgttctgtgtgcc
caagtacatgccggaatgtggagaagaaatgggttctctctagtaaaccagatttattac
taccataatgtgaaatgcagacgtgagatgtttgacaaggatgtagtaatgcttcagaca
ggtgtctccatgatggatccaaatcatttcctgatgatcatgctcagccgctttgaactt
tatcagattttcagtactccagactatggaaaaagatttagttctgagattacccataag
gatgttgttcagcagaacaatactctaatagaagaaatgctatacctcattataatgctt
gttggagagagatttagtcctggagttggacaggtaaatgctacagatgaaatcaagcga
gagattatccatcagttgagtatcaagcctatggctcatagtgaattggtaaagtcttta
cctgaagatgagaacaaggagactggcatggagagtgtaatcgaagcagttgcccatttc
aagaaacctggattaacaggacgaggcatgtatgaactgaaaccagaatgtgccaaagag
ttcaacttgtatttctatcacttttcaagggcagaacagtccaaggcagaagaagcgcaa
cggaaattgaaaagacaaaatagagaagatacagcactcccacctccggtgttgcctcca
ttctgccctctgtttgcaagcctggttaacattttgcagtcagatgtcatgttgtgcatc
atgggaacaattctgcaatgggctgtggaacataatggatatgcctggtcagagtccatg
ctgcaaagggtgttacatttaattggcatggcactacaagaagaaaaacaacatttagag
aatgtcacggaagagcatgtagtaacatttaccttcactcagaagatatcaaaacctggt
gaagcgccaaaaaattctcctagcatactagctatgctggaaacactacaaaatgctccc
tacctagaagtccacaaagacatgattcggtggatattgaagacttttaatgctgttaaa
aagatgagggagagttcacctaccagtcccgtggcagagacagaaggaaccataatggaa
gagagttcaagggacaaagacaaagctgagaggaagagaaaagcagagattgccagactg
cgcagagaaaagatcatggctcagatgtctgaaatgcagcggcattttattgatgaaaac
aaagaactctttcagcagacattagaactggatgcctcaacctctgctgttcttgatcat
agccctgtggcttcagatatgacacttacagcactgggccccgcacaaactcaggttcct
gaacaaagacaattcgttacatgtatattgtgtcaagaggagcaagaagttaaagtggaa
agcagggcaatggtcttggcagcatttgttcagagatcaactgtattatcaaaaaacaga
agtaaatttattcaagatccagaaaaatatgatccattattcatgcaccctgatctgtct
tgtggaacacacactagtagctgtgggcacattatgcatgcccattgttggcaaaggtat
tttgattccgttcaagctaaagaacagcgaaggcaacagagattacgcttacatacgagc
tatgatgtagaaaacggagaattcctttgccccctttgtgaatgcttgagtaatactgtt
attcctctgctgcttcctccaagaaatatttttaacaacaggttaaatttttcagaccaa
ccaaatctgactcagtggattagaacaatatctcagcaaataaaagcattacagtttctt
aggaaagaagaaagtactcctaataatgcctctacaaagaattcagaaaatgtggatgaa
ttacagctccctgaagggttcaggcctgattttcgtcctaagatcccttattctgagagc
ataaaagaaatgctaacgacatttggaactgctacctacaaggtgggactaaaggttcat
cccaatgaagaggatcctcgtgttcccataatgtgttggggtagctgcgcgtacaccatc
caaagcatagaaagaattttgagtgatgaagataaaccattgtttggtcctttaccttgc
agactggatgactgtcttaggtcattgacgagatttgccgcagcacactggacagtggca
tcagtttcagtggtgcaaggacatttttgtaaactttttgcatcactggtgcctaatgac
agccatgaggaacttccatgcatattagatattgacatgtttcatttattggtgggcttg
gtgcttgcatttcctgcgttgcagtgtcaggatttttcagggatcagccttggcactgga
gaccttcacattttccatctggttactatggcacacatcatacagatcttacttacctca
tgtacagaagagaatggcatggatcaagaaaatcccccttgtgaagaagaatcagcagtt
cttgctttgtataaaacacttcaccagtatacgggaagtgccttgaaagaaataccatcc
ggctggcatctgtggaggagtgtcagagctggaatcatgcctttcctgaagtgttctgct
ttattttttcattacttaaatggagttccttccccacccgacattcaagttcctggaaca
agccattttgaacatttatgtagctatctttccctaccaaacaacctcatttgccttttt
caagaaaatagtgagataatgaattcactgattgaaagttggtgccgtaacagtgaagtt
aaaagatatctagaaggtgaaagagatgctataagatatccaagagaatctaacaaatta
ataaaccttccagaggattacagcagcctcattaatcaagcatccaatttctcgtgcccg
aaatcaggtggtgataagagcagagccccaactctgtgccttgtgtgcggatctctgctg
tgctcccagagttactgctgccagactgaactggaaggggaggatgtaggagcctgcaca
gctcacacctactcctgtggctctggagtgggcatcttcctgagagtacgggaatgtcag
gtgctatttttagctggcaaaaccaaaggctgtttttattctcctccttaccttgatgac
tatggggagaccgaccagggactcagacggggaaatcctttacatttatgcaaagagcga
ttcaagaagattcagaagctctggcaccaacacagtgtcacagaggaaattggacatgca
caggaagccaatcagacactggttggcattgactggcaacatttataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (24)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (51)   
   RefSeq(nuc) (21)   
   GenBank (15)   
   EMBL (15)   
3D Structure (6)   
   PDB (6)   
Protein domain (4)   
   Pfam (4)   
All databases (117)   

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