KEGG   Homo sapiens (human): 23389
Entry
23389             CDS       T01001                                 
Symbol
MED13L, MRFACD, PROSIT240, THRAP2, TRAP240L
Name
(RefSeq) mediator complex subunit 13L
  KO
K15164  mediator of RNA polymerase II transcription subunit 13
Organism
hsa  Homo sapiens (human)
Pathway
hsa04919  Thyroid hormone signaling pathway
Disease
H02463  Syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    23389 (MED13L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    23389 (MED13L)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Mediator complex
    CDK-module
     23389 (MED13L)
SSDB
Motif
Pfam: Med13_C MID_MedPIWI Med13_N
Other DBs
NCBI-GeneID: 23389
NCBI-ProteinID: NP_056150
OMIM: 608771
HGNC: 22962
Ensembl: ENSG00000123066
UniProt: Q71F56
Position
12:complement(115958576..116277693)
AA seq 2210 aa
MTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSF
IRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRT
LLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTS
VEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQ
YFYPMVLKKKEESKEEDELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSVAS
AGGHIAVGQQGLGSVKDPSNCGMPLTPPTSPEQAILGESGGMQSAASHLVSQDGGMITMH
SPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPASNPATWDFVDPTQR
VSCSCSRHKLLKRCAVGPNRPPTVSQPGFSAGPSSSSSLPPPASSKHKTAERQEKGDKLQ
KRPLIPFHHRPSVAEELCMEQDTPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQM
NLNPMDSPHSPISPLPPTLSPQPRGQETESLDPPSVPVNPALYGNGLELQQLSTLDDRTV
LVGQRLPLMAEVSETALYCGIRPSNPESSEKWWHSYRLPPSDDAEFRPPELQGERCDAKM
EVNSESTALQRLLAQPNKRFKIWQDKQPQLQPLHFLDPLPLSQQPGDSLGEVNDPYTFED
GDIKYIFTANKKCKQGTEKDSLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATK
TDVRQDNAAGRAGSSSLTQVTDLAPSLHDLDNIFDNSDDDELGAVSPALRSSKMPAVGTE
DRPLGKDGRAAVPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGISSETVTALGMMES
PMVSMVSTQLTEFKMEVEDGLGSPKPEEIKDFSYVHKVPSFQPFVGSSMFAPLKMLPSHC
LLPLKIPDACLFRPSWAIPPKIEQLPMPPAATFIRDGYNNVPSVGSLADPDYLNTPQMNT
PVTLNSAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQG
SPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMNI
KGADVGLYIPDSSNEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERR
LMMCQSTFLPQVEGTKKPQEPPISLLLLLQNQHTQPFASLNFLDYISSNNRQTLPCVSWS
YDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHSWPHSNVLDISMLSS
QDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPL
PIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRD
LSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTDELVSEWFNQPWSGEENDNHSRLK
LYAQVCRHHLAPYLATLQLDSSLLIPPKYQTPPAAAQGQATPGNAGPLAPNGSAAPPAGS
AFNPTSNSSSTNPAASSSASGSSVPPVSSSASAPGISQISTTSSSGFSGSVGGQNPSTGG
ISADRTQGNIGCGGDTDPGQSSSQPSQDGQESVTERERIGIPTEPDSADSHAHPPAVVIY
MVDPFTYAAEEDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMKDEQ
VFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPF
ILAPIKDKQTELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCVVNIAL
PNRSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECS
LQTISKKLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNM
QSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIG
ILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYF
VSTAKAENLPQWFWSSCPQAQNQCPLFLKASLHHHISVAQTDELLPARNSQRVPHPLDSK
TTSDVLRFVLEQYNALSWLTCNPATQDRTSCLPVHFVVLTQLYNAIMNIL
NT seq 6633 nt   +upstreamnt  +downstreamnt
atgactgcggcagcgaactgggtggcgaacggggcgagcctggaggattgtcactccaac
ctcttttcgctggctgaactcacgggaatcaaatggcgtaggtacaattttggagggcat
ggggactgtggacccataatttcagccccagcccaagatgatccaattctgttaagtttc
atccgctgtctgcaagctaacctgctttgtgtatggcgtcgtgatgtcaaaccagattgc
aaagagttatggatattctggtggggagatgaacccaacctagtgggtgtaatacatcat
gaactgcaggttgtggaagaaggactctgggaaaatggcctttcctatgaatgtaggacg
ctgctcttcaaagcgatccacaatctgttagaaaggtgcctaatggataagaacttcgtt
aggattgggaaatggtttgtccgaccctacgaaaaggatgaaaagccagtcaacaaaagt
gagcatttgtcctgtgctttcacattctttctgcatggagaaagtaatgtatgcacaagt
gtggagattgcccagcaccagccaatttatttgatcaatgaggagcatatacacatggct
cagtcttcacctgcaccatttcaagtactggtaagtccttatggcttaaatgggacgcta
acaggccaagcatacaagatgtcagacccagccactcgtaagttgattgaggaatggcag
tatttctacccgatggtgctaaaaaagaaagaagaatcgaaagaggaagacgagttggga
tatgatgatgatttccctgtggcagttgaagtaattgttggtggtgttcggatggtttac
ccttcagcatttgttttgatctctcagaatgacatcccggttcctcagagtgttgccagt
gctggaggccacattgcagttgggcagcaagggcttggtagtgtgaaggacccaagtaac
tgtgggatgcctctgacccctcccacctctccagaacaggctatcctaggtgagagtgga
ggtatgcagagtgctgccagtcacctggtttcccaagatggagggatgataacgatgcac
agtccaaagagatcggggaagattcctccaaaactccacaatcatatggtccatcgagtc
tggaaggaatgcatcctcaacagaacccagtccaagaggagccaaatgtcaactccaact
cttgaagaagagcctgctagcaatcctgctacttgggattttgtggatccaacccaaaga
gtcagctgttcttgttccaggcataagcttttaaaacgttgtgcagtcgggcccaatcga
cctcccacagtatctcaaccagggttcagtgcaggaccatcatcatcttcatctttacca
cctcctgcttcttctaagcacaaaacagcagaaagacaggaaaaaggagacaagctgcaa
aagagacccttaataccatttcaccataggccctctgtggccgaagaattatgcatggag
caagatacaccaggacagaaactagggttggcagggatagactcctccttagaggtgtct
agcagtaggaaatatgataagcaaatggccgtgccttccagaaatacaagcaagcaaatg
aatctgaatcctatggattcacctcattcccctatatcccctctgccaccaacactcagc
cctcagccacgaggtcaggaaacagagagtttggacccaccatcggtccctgtgaatcca
gccctttatggaaatggactagaactccagcagttgtctactctggatgacagaactgtc
ctcgtaggccaaagactgcctctcatggcagaggtcagcgagacagccttatattgtggg
attaggccctcgaacccggagtcatcagaaaagtggtggcatagttatcgtctcccaccc
agtgatgatgctgagttcaggcctccagagctccagggtgagagatgtgatgccaaaatg
gaggtaaactcagagagcactgcattgcaaagactcttagcacaacctaacaaacggttt
aaaatctggcaagacaaacagccccagttgcagccactccacttccttgacccattgcct
ctatcacaacaacctggagacagtttgggagaagtgaatgacccatatacctttgaagat
ggtgacataaaatacatctttacagccaacaagaaatgcaaacaagggacggagaaagat
tccctgaaaaagaataagtcagaggatggatttggtaccaaggatgtcactacaccaggt
cattccacgccggtgcctgatgggaaaaatgccatgtctattttcagttctgctactaaa
acagatgtccggcaggataatgctgctggcagagctggctccagtagccttacacaggta
acagatttggcaccttccctgcatgacttagacaacatctttgataattctgatgacgac
gaacttggggctgtatcacctgctctgcgctcatcaaaaatgcctgcagttgggacagaa
gaccgacctcttgggaaggatggaagagctgctgttccttatccaccaacagttgcagac
ttgcaaaggatgtttcccactccaccatctttggaacagcatcctgcattttctcctgtg
atgaattataaagatgggatcagctcagagacagtgacagcattaggcatgatggagagc
cctatggtcagtatggtttcaacacaactcacagaattcaaaatggaagtggaagatgga
ttaggaagtcccaagcccgaggaaattaaggacttttcatatgtgcacaaagttccatcc
tttcaaccttttgtgggatcctccatgtttgctccactgaagatgttgccgagccattgt
ttgctacctctgaagatacctgatgcctgtctgtttcggccttcatgggcaattcctcct
aaaattgaacaactgcccatgccccctgcagccactttcattagagatggctacaataac
gtgcctagtgttgggagcctagcagatccagactatctgaacacaccacagatgaacaca
cccgtgacgttgaacagcgctgccccagccagcaatagtggggcaggagtcctaccatct
ccagcaacccctcgcttctctgtccccacaccacgaacccccaggaccccaagaactccc
agaggtgggggcactgccagtggtcaagggtctgttaagtatgatagcaccgatcaagga
tcaccagcctccaccccctctactacacggcccctcaactctgtggagcccgccaccatg
cagccaattcccgaagcccacagcctctatgttaccctgattctctccgattccgtgatg
aatatctttaaagacagaaactttgacagctgttgcatctgtgcctgcaacatgaacatc
aaaggggcggatgtcgggctttacatccccgattcttccaatgaggaccagtaccgctgt
acctgtgggtttagtgcgattatgaaccgcaaacttggctacaattcaggactcttcctt
gaagatgagttggatatttttgggaagaattctgatattggtcaggctgcagagaggcgc
ttaatgatgtgtcagtccaccttccttcctcaggtggaaggaaccaaaaaaccccaggag
ccacccataagccttctcctcctcctccagaatcaacacacacaaccttttgcttcactg
aatttcctggactacatttcctctaacaatcgccaaactcttccctgtgtaagctggagt
tatgaccgggtgcaagcagataataatgattactggacggaatgctttaatgcgttggag
caggggcggcagtatgtggataaccccactggtggaaaagtggacgaagctctggtgaga
agtgccactgtgcactcttggcctcacagcaatgtgctggacatcagcatgctctcctcc
caggatgtggttcgtatgctgttgtccctgcagccctttctccaagatgccatccaaaag
aagcgcacgggcaggacctgggagaacatccagcatgtgcagggaccactcacttggcag
cagttccataaaatggcaggacggggaacctacggttcggaagaatctcctgagccgttg
cccatccccactctgctggtaggctatgacaaggatttcctcaccatctcgccattctcc
ttgccgttttgggagaggctcttgttggacccatatgggggccaccgtgatgttgcctat
attgtggtgtgtccagaaaatgaggccttgctcgaaggagccaaaactttcttcagggac
ttgagtgctgtatacgagatgtgtaggcttgggcagcacaagcccatctgcaaagtgcta
cgtgacgggatcatgcgcgtgggaaaaactgtggcacagaagctgacagatgagcttgtg
agtgagtggtttaaccagccttggagcggcgaggagaatgacaatcattccagactcaaa
ctttatgcgcaagtttgccgccatcacctagcaccttatttagccactctgcagcttgat
agcagcctattgataccacctaaataccagaccccaccagcagcagcacagggacaagct
acgccagggaatgctgggcccttagctccaaatggatcagcagctcccccagctggcagt
gcatttaatcccacctcgaatagtagttctacaaatcctgcagcaagtagttctgcatct
ggttcctctgtgccaccggtctcatcgtctgcctctgctcctggtattagccagataagc
actacctcttcttcaggattcagtggtagtgttggagggcagaaccccagcactgggggc
atttctgcggatagaacgcaagggaacataggctgtggtggagacactgaccctgggcag
agctcttctcagccctcacaggatggacaagagagtgttacagaaagggagagaatagga
attcccacggagcctgactctgcagacagccatgcccaccctccagctgttgtcatttac
atggtggacccgttcacgtatgctgcagaggaggactccacttctgggaacttttggctg
ttgagcttgatgcgctgctacacagaaatgctggataatttacctgagcatatgagaaat
tctttcattctccagattgtgccttgccagtacatgctgcagacaatgaaggatgagcaa
gttttctacattcaatacttgaagtccatggcattttcagtgtactgccagtgcaggcga
ccactgcctacacagatccacattaaatccctcacgggatttgggcctgcagccagcatt
gagatgaccctcaagaaccctgagcggcccagcccaatccagctttactcccctcccttt
atattggccccaatcaaagacaagcagacagagctgggagagacgtttggtgaggcgagc
cagaaatacaatgtgctcttcgtgggctattgtctgtctcacgaccagcgctggcttttg
gcttcctgcactgacctccatggggaattattagagacctgcgttgtaaatattgcttta
ccaaacaggtcacggaggagtaaagtatctgcacgtaaaattggactacagaagttatgg
gagtggtgcatagggattgtccaaatgacatctctaccctggagagttgtaatcgggcga
cttgggcgtcttggccatggggagcttaaagattggagtatcctccttggagaatgttca
ctacagacaatcagcaaaaagctcaaggatgtgtgccggatgtgtggaatctctgccgca
gactctccttctatccttagtgcctgcctggttgccatggagccccaggggtcctttgta
gtgatgccagatgctgtcacaatgggctctgtttttggccgaagtactgcactgaacatg
cagtcatctcagctcaacacccctcaagatgcttcttgtacacacatcttggtgttccca
acatcatcaaccatccaggtggctccagccaactaccccaatgaagatgggtttagcccc
aacaatgatgatatgtttgttgaccttccattcccagatgatatggacaatgatattggc
atattaatgactgggaacctccattcctctcccaactcttccccagtaccctccccaggc
tctccttctggaattggtgtgggctctcacttccagcatagtcggagccagggtgagcgt
cttctttctagagaagcaccagaggagctaaagcagcagcccctggcccttgggtatttt
gtatcaactgccaaagctgagaatcttccccagtggttttggtcatcgtgtccccaggct
caaaaccagtgccctctcttcttaaaggcttcgctgcatcaccacatttcagtagcacag
acagacgaacttctgcctgccaggaattctcagcgggttccacaccctcttgactccaaa
accacgtcggatgttttaaggtttgttttggagcagtacaacgctctgtcctggctcacg
tgcaatccggccacccaggaccgtacttcctgccttcccgtccactttgtggtgctcact
cagttgtacaatgccatcatgaatatactttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (38)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (43)   
   RefSeq(nuc) (15)   
   GenBank (14)   
   EMBL (14)   
Protein domain (3)   
   Pfam (3)   
All databases (103)   

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