KEGG   Homo sapiens (human): 2352
Entry
2352              CDS       T01001                                 
Symbol
FOLR3, FR-G, FR-gamma, FRgamma, gamma-hFR
Name
(RefSeq) folate receptor gamma
  KO
K13649  folate receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa01523  Antifolate resistance
hsa04144  Endocytosis
hsa04981  Folate transport and metabolism
hsa05215  Prostate cancer
Drug target
Pafolacianine (DG03206): D12249 D12250<US>
Vintafolide: D10434
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    2352 (FOLR3)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    2352 (FOLR3)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    2352 (FOLR3)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    2352 (FOLR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    2352 (FOLR3)
   04147 Exosome [BR:hsa04147]
    2352 (FOLR3)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    2352 (FOLR3)
Transporters [BR:hsa02000]
 Other transporters
  Others
   2352 (FOLR3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   2352 (FOLR3)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Receptors
  2352 (FOLR3)
SSDB
Motif
Pfam: Folate_rec Glyco_transf_8C
Other DBs
NCBI-GeneID: 2352
NCBI-ProteinID: NP_000795
OMIM: 602469
HGNC: 3795
Ensembl: ENSG00000110203
UniProt: P41439
Position
11:72135725..72139892
AA seq 245 aa
MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW
KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV
NQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFES
YFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSR
GIIDS
NT seq 738 nt   +upstreamnt  +downstreamnt
atggacatggcctggcagatgatgcagctgctgcttctggctttggtgactgctgcgggg
agtgcccagcccaggagtgcgcgggccaggacggacctgctcaatgtctgcatgaacgcc
aagcaccacaagacacagcccagccccgaggacgagctgtatggccagtgcagtccctgg
aagaagaatgcctgctgcacggccagcaccagccaggagctgcacaaggacacctcccgc
ctgtacaactttaactgggatcactgtggtaagatggaacccacctgcaagcgccacttt
atccaggacagctgtctctatgagtgctcacccaacctggggccctggatccggcaggtc
aaccagagctggcgcaaagagcgcattctgaacgtgcccctgtgcaaagaggactgtgag
cgctggtgggaggactgtcgcacctcctacacctgcaaaagcaactggcacaaaggctgg
aattggacctcagggattaatgagtgtccggccggggccctctgcagcacctttgagtcc
tacttccccactccagccgccctttgtgaaggcctctggagccactccttcaaggtcagc
aactatagtcgagggagcggccgctgcatccagatgtggtttgactcagcccagggcaac
cccaatgaggaggtggccaagttctatgctgcggccatgaatgctggggccccgtctcgt
gggattattgattcctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (12)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
Protein domain (2)   
   Pfam (2)   
All databases (39)   

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