| Entry |
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| Gene name |
PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101
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| Definition |
(RefSeq) phosphoinositide-3-kinase regulatory subunit 5
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| KO |
| K21290 | phosphoinositide-3-kinase regulatory subunit 5/6 |
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| Organism |
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| Pathway |
| hsa04072 | Phospholipase D signaling pathway |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Network |
nt06124 Chemokine signaling (viruses) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06167 Human cytomegalovirus (HCMV) nt06224 CXCR signaling |
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| Element |
| N00153 | CCR/CXCR-GNB/G-PI3K-RAC signaling pathway |
| N00154 | CXCR-GNB/G-PI3K-AKT signaling pathway |
| N00158 | KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway |
| N00178 | KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway |
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| Disease |
| H00848 | Ataxia with ocular apraxia |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
23533 (PIK3R5)
04072 Phospholipase D signaling pathway
23533 (PIK3R5)
04022 cGMP-PKG signaling pathway
23533 (PIK3R5)
04151 PI3K-Akt signaling pathway
23533 (PIK3R5)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
23533 (PIK3R5)
04062 Chemokine signaling pathway
23533 (PIK3R5)
09152 Endocrine system
04921 Oxytocin signaling pathway
23533 (PIK3R5)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
23533 (PIK3R5)
09156 Nervous system
04725 Cholinergic synapse
23533 (PIK3R5)
09160 Human Diseases
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
23533 (PIK3R5)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
23533 (PIK3R5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
23533 (PIK3R5)
Membrane trafficking [BR:hsa04131]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
23533 (PIK3R5)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
17p13.1
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| AA seq |
880 aa  
MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE
QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC
SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN
KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA
SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI
LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS
LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK
FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP
QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR
LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW
EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL
YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG
DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV
VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK
PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP |
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| NT seq |
2643 nt  +upstreamnt +downstreamnt
atgcagccaggggccacgacatgcacggaggaccgcatccagcatgccctggaacgctgc
ctgcatggactcagcctcagccgccgctccacctcctggtcagctgggctgtgtctgaac
tgctggagcctgcaggagctggtcagcagggacccgggccacttccttatcctccttgag
cagatcctgcagaagacccgagaggtccaggagaagggcacctacgacctgctcaccccg
ctggccctgctcttctattccactgttctttgtacaccacacttcccaccagactcggat
ctccttctgaaggcagccagcacctaccaccggttcctgacctggcctgttccttactgc
agcatctgccaggagctgctcaccttcattgatgctgaactcaaggccccagggatctcc
taccagagactggtgagggctgagcagggcctgcccatcaggagtcaccgcagctccacc
gtcaccgtgctgctgctgaacccagtggaagtgcaggccgagttccttgctgtagccaat
aagctgagtacgcccggacactcgcctcacagtgcctacaccaccctgctcctgcacgcc
ttccaggccacctttggggcccactgtgacgtcccgggcctgcactgcaggctacaggcc
aagaccctggcagagcttgaggacatcttcacggagaccgcagaggcacaggagctggca
tctggcatcggggatgctgcagaggcccggcggtggctcaggaccaagctgcaggcggtg
ggagaaaaagctggcttccctggggtgttagacactgcaaaaccagggaagctccacacc
atccccatccctgtcgccaggtgctacacctacagctggagccaggacagctttgacatc
ctgcaggaaatcctgctcaaggaacaggagctactccagccagggatcctgggagatgat
gaagaggaggaagaggaggaggaggaggtggaggaggacttggaaactgacgggcactgt
gccgagagagattccctgctctccaccagctctttggcgtcccatgactccaccttgtcc
cttgcatcctcccaggcctcggggccggccctctcgcgccatctgctgacttcctttgtc
tcaggcctctctgatggcatggacagcggctacgtggaggacagcgaggagagctcctcc
gagtggccttggaggcgtggcagccaggaacgccgaggccaccgcaggcctgggcagaag
ttcatcaggatctataaactcttcaagagcaccagccagctggtactgcggagggactct
cggagcctggagggcagctcggacacggccctgcccctgaggcgggcagggagcctctgc
agccccctggacgaaccagtatcacccccttcccgggcccagcgctcccgctccctgccc
cagcccaaactcggtacccagctgcccagctggcttctggcccctgcttcacgcccccag
cgccgccgccccttcctgagtggagatgaggatcccaaggcttccacgctacgtgttgtg
gtctttggctccgatcggatttcagggaaggtggctcgggcgtacagcaaccttcggcgg
ctggagaacaatcgcccactcctcacacggttcttcaaacttcagttcttctacgtgcct
gtgaagcgaagtcatgggaccagccctggtgcctgtccaccccctcggagccagacgccc
tcacccccgacagactcccctaggcacgccagccctggagagctgggcaccaccccatgg
gaggagagcaccaatgacatctcccactacctcggcatgctggacccctggtatgagcgc
aatgtactgggcctcatgcacctgccccctgaagtcctgtgccagcagtccctgaaggct
gaagcccaggccctggagggctccccaacccagctgcccatcctggctgacatgctactc
tactactgccgctttgccgccagaccggtgctgctgcaagtctatcagaccgagctgacc
ttcatcactggggagaagacgacagagatcttcatccactccttggagctgggtcactcc
gctgccacacgtgccatcaaggcgtcaggtcctggcagcaagcggctgggcatcgatggc
gaccgggaggctgttcctctaacactacagattatttacagcaagggggccatcagtgga
cgaagtcgctggagcaacctggagaaggtctgtacctccgtgaacctcaacaaggcctgc
cggaagcaggaggagctggattccagcatggaggccctgacgctaaacctgacagaagtg
gtgaaaaggcagaactccaaatccaagaagggctttaaccagattagcacatcgcagatc
aaagtggacaaggtgcagatcatcggctccaacagctgcccctttgctgtgtgcctggac
caggatgagagaaagatcctgcagagtgtagtcagatgtgaggtctcaccgtgctacaag
ccagagaagagcgacctctcctcaccaccccagacgcctcctgacctgccggcccaggcc
gcacctgatctctgctcccttctctgcctgcccatcatgactttcagtggagctctgccc
tag |
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