Entry |
|
Symbol |
PDSS1, COQ1, COQ10D2, COQ1A, DPS, SPS, TPRT, TPT, TPT_1, hDPS1
|
Name |
(RefSeq) decaprenyl diphosphate synthase subunit 1
|
KO |
|
Organism |
|
Pathway |
hsa00900 | Terpenoid backbone biosynthesis |
|
Disease |
H00999 | Coenzyme Q10 deficiency |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
23590 (PDSS1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01006 Prenyltransferases [BR:hsa01006]
23590 (PDSS1)
Enzymes [BR:hsa01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.91 all-trans-decaprenyl-diphosphate synthase
23590 (PDSS1)
Prenyltransferases [BR:hsa01006]
Terpene biosynthesis
Prenyl diphosphate synthase
23590 (PDSS1)
|
SSDB |
|
Motif |
|
Other DBs |
|
Position |
10:26697701..26746798
|
AA seq |
415 aa
MASRWWRWRRGCSWKPAARSPGPGSPGRAGPLGPSAAAEVRAQVHRRKGLDLSQIPYINL
VKHLTSACPNVCRISRFHHTTPDSKTHSGEKYTDPFKLGWRDLKGLYEDIRKELLISTSE
LKEMSEYYFDGKGKAFRPIIVALMARACNIHHNNSRHVQASQRAIALIAEMIHTASLVHD
DVIDDASSRRGKHTVNKIWGEKKAVLAGDLILSAASIALARIGNTTVISILTQVIEDLVR
GEFLQLGSKENENERFAHYLEKTFKKTASLIANSCKAVSVLGCPDPVVHEIAYQYGKNVG
IAFQLIDDVLDFTSCSDQMGKPTSADLKLGLATGPVLFACQQFPEMNAMIMRRFSLPGDV
DRARQYVLQSDGVQQTTYLAQQYCHEAIREISKLRPSPERDALIQLSEIVLTRDK |
NT seq |
1248 nt +upstreamnt +downstreamnt
atggcctcgcgctggtggcggtggcggcgcggctgctcctggaagccggcggcgcggagc
cccgggcccggctcccccggccgtgcgggaccgttggggccgagcgccgctgccgaagtc
cgcgcgcaggttcataggcggaagggacttgacttgtctcagataccctatattaatctt
gtgaagcatttaacatctgcctgtccaaatgtatgtcgtatatcacggtttcatcacaca
accccagacagtaaaacacacagtggtgaaaaatacaccgatcctttcaaactcggttgg
agagacttgaaaggtctgtatgaggacattagaaaggaactgcttatatcaacatcagaa
cttaaggaaatgtctgagtactactttgatgggaaagggaaagcctttcgaccaattatt
gtggcgctaatggcccgagcatgcaatattcatcataacaactcccgacatgtgcaagcc
agccagcgcgccatagccttaattgcagaaatgatccacactgctagtctggttcacgat
gacgttattgacgatgcaagttctcgaagaggaaaacacacagttaataagatctggggt
gaaaagaaggctgttcttgctggagatttaattctttctgcagcatctatagctctggca
cgaattggaaatacaactgttatatctattttaacccaagttattgaagatttggtgcgt
ggtgaatttcttcagctcgggtcaaaagaaaatgagaatgaaagatttgcacactacctt
gagaagacattcaagaagaccgccagcctgatagccaacagttgtaaagcagtctctgtt
ctaggatgtcccgacccagtggtgcatgagatcgcctatcagtacggaaaaaatgtagga
atagcttttcagctaatagatgatgtattggacttcacctcgtgttctgaccagatgggc
aaaccaacatcagctgatctgaagctcgggttagccactggtcctgtcctgtttgcctgt
cagcagttcccagaaatgaatgctatgatcatgcgacggttcagtttgcctggagatgta
gacagagctcgacagtatgtactacagagtgatggtgtgcaacaaacaacctacctcgcc
cagcagtactgccatgaagcaataagagagatcagtaaacttcgaccatccccagaaaga
gatgccctcattcagctttcagaaattgtactcacaagagataaatga |