KEGG   Homo sapiens (human): 23770
Entry
23770             CDS       T01001                                 
Symbol
FKBP8, FKBP38, FKBPr38
Name
(RefSeq) FKBP prolyl isomerase 8
  KO
K09574  FK506-binding protein 8 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
Network
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06536  Mitophagy
  Element
N01137  PINK-Parkin-mediated autophagosome formation
N01138  Mutation-inactivated OPTN to PINK-Parkin-mediated autophagosome formation
N01139  Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
N01757  PINK-Parkin-independent ubiquitin-mediated mitophagy, ubiquitin E3 ligase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    23770 (FKBP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    23770 (FKBP8)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    23770 (FKBP8)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     23770 (FKBP8)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Other calcineurin-interacting proteins
     23770 (FKBP8)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    23770 (FKBP8)
SSDB
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_16 TPR_14 Fis1_TPR_C TPR_19 TPR_11 TPR_8 TPR_9 TPR_17 TPR_12 ANAPC3 TPR_7 TPR_YpiA_C TPR_CcmH_CycH TPR_6 RMD1-3 TPR_Slam ARM_TT21_5th CABIN1_N NatA_aux_su ARM_TT21 UBL_UBAC1
Other DBs
NCBI-GeneID: 23770
NCBI-ProteinID: NP_001295302
OMIM: 604840
HGNC: 3724
Ensembl: ENSG00000105701
UniProt: Q14318 B2R8G6
Structure
Position
19:complement(18531763..18543573)
AA seq 412 aa
MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ
PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG
QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG
PQGRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA
ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE
HQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTE
TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN
NT seq 1239 nt   +upstreamnt  +downstreamnt
atggcatcgtgtgctgaaccctctgagccctctgccccactgcccgccggggtcccaccg
ctcgaggacttcgaggtactggatggggttgaggatgcagagggtgaggaggaagaggag
gaggaagaggaggaagaggatgacctgagtgagctgccaccgctggaggacatgggacaa
cccccggcggaggaggctgagcagcctggggccctggcccgagagttccttgctgccatg
gagcccgagcccgccccagccccggccccagaagagtggctggacattctggggaacggg
ctgttgaggaagaagacgctggtcccagggccgccaggttcgagccgcccggtcaagggc
caggtggtcaccgtacatctgcagacgtcgctggagaatggcacacgggtgcaggaggag
ccggagctggtgttcactctgggtgactgtgacgtcatccaggccctggatctcagtgtc
ccactcatggacgtgggggagacggccatggtcactgctgactccaagtactgctacggc
ccccaaggcaggagcccatacatccccccgcacgcggccctgtgcctggaggtgaccctg
aagacggctgtggacgggcctgacctggagatgctcacggggcaggagcgcgtggccctg
gccaaccggaagcgggagtgcggcaacgcccactaccagcgggcggacttcgtcctggcc
gccaactcctacgacctcgccatcaaggctatcacctccagcgccaaagtggacatgacg
ttcgaggaggaggcacagctcctgcagttgaaggtgaagtgtctgaacaacctggcggcc
tcgcagctgaagctcgaccactaccgcgcagccctgcgctcctgcagccttgtgctggag
caccagccagacaacatcaaggctctcttccgcaagggcaaggtgctggcccagcagggg
gagtacagtgaggccatccccatcctgagggcagccctgaagctggaaccttccaacaag
acgatccacgcagagctctcaaagctggtgaagaagcatgcggcgcagcggagcacggag
accgccttgtaccggaaaatgctgggcaaccccagccggctgcctgctaagtgccctggc
aagggtgcctggtccatcccatggaagtggctgtttggggcgactgctgttgccttgggg
ggtgtggcactctctgtggtcatcgctgccaggaactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (21)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
3D Structure (6)   
   PDB (6)   
Protein domain (21)   
   Pfam (21)   
All databases (90)   

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