KEGG   Homo sapiens (human): 246213Help
Entry
246213            CDS       T01001                                 

Gene name
SLC17A8, DFNA25, VGLUT3
Definition
(RefSeq) solute carrier family 17 member 8
  KO
K12302  MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa04721  Synaptic vesicle cycle
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa05033  Nicotine addiction
Disease
H00604  Deafness, autosomal dominant
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Organismal Systems
  Nervous system
   04724 Glutamatergic synapse
    246213 (SLC17A8)
   04723 Retrograde endocannabinoid signaling
    246213 (SLC17A8)
   04721 Synaptic vesicle cycle
    246213 (SLC17A8)
 Human Diseases
  Substance dependence
   05033 Nicotine addiction
    246213 (SLC17A8)
Transporters [BR:hsa02000]
 Solute Carrier Family (SLC)
  SLC17: Vesicular glutamate transporter
   246213 (SLC17A8)
 Major Facilitator Superfamily (MFS)
  Organic acid transporters
   Anion:cation symporter (ACS) family [TC:2.A.1.14]
    246213 (SLC17A8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MFS_1
Motif
Other DBs
NCBI-GeneID: 246213
NCBI-ProteinID: NP_647480
OMIM: 607557
HGNC: 20151
Ensembl: ENSG00000179520
Vega: OTTHUMG00000170358
Pharos: Q8NDX2(Tbio)
UniProt: Q8NDX2
Position
12q23.1
AA seq 589 aa AA seqDB search
MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTTEEEDNIELNEEGRPVQTSRP
SPPLCDCHCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTA
QFNWDPETVGLIHGSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARV
HYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGV
LVQYIGWSSVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNEEKTYIETSIGEGANVVSL
SKFSTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPH
MVMTIVVPIGGQLADYLRSRQILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFL
VLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTRHKTREEW
QNVFLIAALVHYSGVIFYGVFASGEKQEWADPENLSEEKCGIIDQDELAEEIELNHESFA
SPKKKMSYGATSQNCEVQKKEWKGQRGATLDEEELTSYQNEERNFSTIS
NT seq 1770 nt NT seq  +upstreamnt  +downstreamnt
atgccttttaaagcatttgataccttcaaagaaaaaattctgaaacctgggaaggaagga
gtgaagaacgccgtgggagattctttgggaattttacaaagaaaaatcgatgggacaact
gaggaagaagataacattgagctgaatgaagaaggaaggccggtgcagacgtccaggcca
agccccccactctgcgactgccactgctgcggcctccccaagcgttacatcattgctatc
atgagtgggctgggattctgcatttcctttgggatccggtgcaatcttggagttgccatt
gtggaaatggtcaacaatagcaccgtatatgttgatggaaaaccggaaattcagacagca
cagtttaactgggatccagaaacagtgggccttatccatggatcttttttctggggctat
attatgacacaaattccaggtggtttcatttcaaacaagtttgctgctaacagggtcttt
ggagctgccatcttcttaacatcgactctgaacatgtttattccctctgcagccagagtg
cattacggatgcgtcatgtgtgtcagaattctgcaaggtttagtggagggtgtgacctac
ccagcctgccatgggatgtggagtaagtgggcaccacctttggagagaagccgactggcc
acaacctctttttgtggttcctatgcaggggcagtggttgccatgcccctggctggggtg
ttggtgcagtacattggatggtcctctgtcttttatatttatggcatgtttgggattatt
tggtacatgttttggctgttgcaggcctatgagtgcccagcagctcatccaacaatatcc
aatgaggagaagacctatatagagacaagcataggagagggggccaacgtggttagtcta
agtaaatttagtaccccatggaaaagatttttcacatctttgccggtttatgcaatcatt
gtggcaaatttttgcagaagctggaccttttatttgctcctcataagtcagcctgcttat
tttgaagaggtctttggatttgcaataagtaaggtgggtctcttgtcagcagtcccacac
atggttatgacaatcgttgtacctattggaggacaattggctgattatttaagaagcaga
caaattttaaccacaactgctgtcagaaaaatcatgaactgtggaggttttggcatggag
gcaaccttactcctggtggttggcttttcgcataccaaaggggtggctatctcctttctg
gtacttgctgtaggatttagtggcttcgctatttcaggttttaatgtcaaccacctggac
attgccccacgctatgccagcattctcatggggatctcaaacggagtgggaaccctctct
ggaatggtctgtcccctcattgtcggtgcaatgaccaggcacaagacccgtgaagaatgg
cagaatgtgttcctcatagctgccctggtgcattacagtggtgtgatcttctatggggtc
tttgcttctggggagaaacaggagtgggctgacccagagaatctctctgaggagaaatgt
ggaatcattgaccaggacgaattagctgaggagatagaactcaaccatgagagttttgcg
agtcccaaaaagaagatgtcttatggagccacctcccagaattgtgaagtccagaagaag
gaatggaaaggacagagaggagcgacccttgatgaggaagagctgacatcctaccagaat
gaagagagaaacttctcaactatatcctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (1)   
   Pfam (1)   
All databases (36)   

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