KEGG   Homo sapiens (human): 2495
Entry
2495              CDS       T01001                                 
Symbol
FTH1, FHC, FTH, FTHL6, HFE5, NBIA9, PIG15, PLIF
Name
(RefSeq) ferritin heavy chain 1
  KO
K00522  ferritin heavy chain [EC:1.16.3.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00860  Porphyrin metabolism
hsa04216  Ferroptosis
hsa04217  Necroptosis
hsa04978  Mineral absorption
Network
nt06525  Ferroptosis
  Element
N01588  Fe3+ Ferritin transport
Disease
H00211  Hemochromatosis
H00833  Neurodegeneration with brain iron accumulation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    2495 (FTH1)
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    2495 (FTH1)
   04217 Necroptosis
    2495 (FTH1)
 09150 Organismal Systems
  09154 Digestive system
   04978 Mineral absorption
    2495 (FTH1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2495 (FTH1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.16  Oxidizing metal ions
   1.16.3  With oxygen as acceptor
    1.16.3.1  ferroxidase
     2495 (FTH1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2495 (FTH1)
  Exosomal proteins of bladder cancer cells
   2495 (FTH1)
SSDB
Motif
Pfam: Ferritin Rubrerythrin wnt
Other DBs
NCBI-GeneID: 2495
NCBI-ProteinID: NP_002023
OMIM: 134770
HGNC: 3976
Ensembl: ENSG00000167996
UniProt: P02794
Structure
Position
11:complement(61964285..61967634)
AA seq 183 aa
MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
NES
NT seq 552 nt   +upstreamnt  +downstreamnt
atgacgaccgcgtccacctcgcaggtgcgccagaactaccaccaggactcagaggccgcc
atcaaccgccagatcaacctggagctctacgcctcctacgtttacctgtccatgtcttac
tactttgaccgcgatgatgtggctttgaagaactttgccaaatactttcttcaccaatct
catgaggagagggaacatgctgagaaactgatgaagctgcagaaccaacgaggtggccga
atcttccttcaggatatcaagaaaccagactgtgatgactgggagagcgggctgaatgca
atggagtgtgcattacatttggaaaaaaatgtgaatcagtcactactggaactgcacaaa
ctggccactgacaaaaatgacccccatttgtgtgacttcattgagacacattacctgaat
gagcaggtgaaagccatcaaagaattgggtgaccacgtgaccaacttgcgcaagatggga
gcgcccgaatctggcttggcggaatatctctttgacaagcacaccctgggagacagtgat
aatgaaagctaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (303)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (292)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (61)   
   RefSeq(nuc) (1)   
   GenBank (30)   
   EMBL (30)   
3D Structure (193)   
   PDB (193)   
Protein domain (3)   
   Pfam (3)   
All databases (566)   

Download RDF
DBGET integrated database retrieval system