KEGG   Homo sapiens (human): 2517Help
Entry
2517              CDS       T01001                                 

Gene name
FUCA1, FUCA
Definition
(RefSeq) alpha-L-fucosidase 1
  KO
K01206  alpha-L-fucosidase [EC:3.2.1.51]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00511  Other glycan degradation
hsa04142  Lysosome
Disease
H00141  Fucosidosis
H00422  Glycoproteinoses
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    2517 (FUCA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    2517 (FUCA1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2517 (FUCA1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.51  alpha-L-fucosidase
     2517 (FUCA1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   2517 (FUCA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Alpha_L_fucos Fucosidase_C GHL6
Motif
Other DBs
NCBI-GeneID: 2517
NCBI-ProteinID: NP_000138
OMIM: 612280
HGNC: 4006
Ensembl: ENSG00000179163
Vega: OTTHUMG00000002965
Pharos: P04066(Tchem)
UniProt: P04066
Position
1p36.11
AA seq 466 aa AA seqDB search
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt
atgcgggctccggggatgaggtcgcggccggcgggtcccgcgctgttgctgctgctgctc
ttcctcggagcggccgagtcggtgcgtcgggcccagcctccgcgccgctacaccccagac
tggccgagcctggattctcggccgctgccggcctggttcgacgaagccaagttcggggtg
ttcatccactggggcgtgttctcggtgcccgcctggggcagcgagtggttctggtggcac
tggcagggcgaggggcggccgcagtaccagcgcttcatgcgcgacaactacccgcccggc
ttcagctacgccgacttcggaccgcagttcactgcgcgcttcttccacccggaggagtgg
gccgacctcttccaggccgcgggcgccaagtatgtagttttgacgacaaagcatcacgaa
ggcttcacaaactggccgagtcctgtgtcttggaactggaactccaaagacgtggggcct
catcgggatttggttggtgaattgggaacagctctccggaagaggaacatccgctatgga
ctataccactcactcttagagtggttccatccactctatctacttgataagaaaaatggc
ttcaaaacacagcattttgtcagtgcaaaaacaatgccagagctgtacgaccttgttaac
agctataaacctgatctgatctggtctgatggggagtgggaatgtcctgatacttactgg
aactccacaaattttctttcatggctctacaatgacagccctgtcaaggatgaggtggta
gtaaatgaccgatggggtcagaactgttcctgtcaccatggaggatactataactgtgaa
gataaattcaagccacagagcttgccagatcacaagtgggagatgtgcaccagcattgac
aagttttcctggggctatcgtcgtgacatggcattgtctgatgttacagaagaatctgaa
atcatttcggaactggttcagacagtaagtttgggaggcaactatcttctgaacattgga
ccaactaaagatggactgattgttcccatcttccaagaaaggcttcttgctgttgggaaa
tggctgagcatcaatggggaggctatctatgcctccaaaccatggcgggtgcaatgggaa
aagaacacaacatctgtatggtatacctcaaagggatcggctgtttatgccatttttctg
cactggccagaaaatggagtcttaaaccttgaatcccccataactacctcaactacaaag
ataacaatgctgggaattcaaggagatctgaagtggtccacagatccagataaaggtctc
ttcatctctctaccccagttgccaccctctgctgtccccgcagagtttgcttggactata
aagctgacaggagtgaagtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (36)   
   RefSeq(nuc) (4)   
   GenBank (16)   
   EMBL (16)   
Protein domain (3)   
   Pfam (3)   
All databases (78)   

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