KEGG   Homo sapiens (human): 2530
Entry
2530              CDS       T01001                                 
Symbol
FUT8, CDGF, CDGF1
Name
(RefSeq) fucosyltransferase 8
  KO
K00717  glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00510  N-Glycan biosynthesis
hsa00513  Various types of N-glycan biosynthesis
hsa00533  Glycosaminoglycan biosynthesis - keratan sulfate
hsa01100  Metabolic pathways
hsa05202  Transcriptional misregulation in cancer
Module
hsa_M00075  N-glycan biosynthesis, complex type
Network
nt06015  N-Glycan biosynthesis
nt06240  Transcription (cancer)
  Element
N00120  MLL-ENL fusion to transcriptional activation
N00820  N-Glycan biosynthesis
Disease
H02451  Congenital disorder of glycosylation with defective fucosylation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    2530 (FUT8)
   00513 Various types of N-glycan biosynthesis
    2530 (FUT8)
   00533 Glycosaminoglycan biosynthesis - keratan sulfate
    2530 (FUT8)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    2530 (FUT8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:hsa01003]
    2530 (FUT8)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.68  glycoprotein 6-alpha-L-fucosyltransferase
     2530 (FUT8)
Glycosyltransferases [BR:hsa01003]
 Glycan extension
  N-Glycan
   2530 (FUT8)
SSDB
Motif
Pfam: FUT8_N_cat SH3_9 SH3_1 NodZ SKI
Other DBs
NCBI-GeneID: 2530
NCBI-ProteinID: NP_835368
OMIM: 602589
HGNC: 4019
Ensembl: ENSG00000033170
UniProt: Q9BYC5 Q546E0 A8K8P8
Structure
Position
14:65356842..65744121
AA seq 575 aa
MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDL
RRMAESLRIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQTRNGLGKDHEILRRRIE
NGAKELWFFLQSELKKLKNLEGNELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWR
EKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRT
LILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPR
PPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVI
GVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTK
YPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQ
TLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYS
KGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK
NT seq 1728 nt   +upstreamnt  +downstreamnt
atgcggccatggactggttcctggcgttggattatgctcattctttttgcctgggggacc
ttgctgttttatataggtggtcacttggtacgagataatgaccatcctgatcactctagc
cgagaactgtccaagattctggcaaagcttgaacgcttaaaacaacagaatgaagacttg
aggcgaatggccgaatctctccggataccagaaggccctattgatcaggggccagctata
ggaagagtacgcgttttagaagagcagcttgttaaggccaaagaacagattgaaaattac
aagaaacagaccagaaatggtctggggaaggatcatgaaatcctgaggaggaggattgaa
aatggagctaaagagctctggtttttcctacagagtgaattgaagaaattaaagaactta
gaaggaaatgaactccaaagacatgcagatgaatttcttttggatttaggacatcatgaa
aggtctataatgacggatctatactacctcagtcagacagatggagcaggtgattggcgg
gaaaaagaggccaaagatctgacagaactggttcagcggagaataacatatcttcagaat
cccaaggactgcagcaaagccaaaaagctggtgtgtaatatcaacaaaggctgtggctat
ggctgtcagctccatcatgtggtctactgcttcatgattgcatatggcacccagcgaaca
ctcatcttggaatctcagaattggcgctatgctactggtggatgggagactgtatttagg
cctgtaagtgagacatgcacagacagatctggcatctccactggacactggtcaggtgaa
gtgaaggacaaaaatgttcaagtggtcgagcttcccattgtagacagtcttcatccccgt
cctccatatttacccttggctgtaccagaagacctcgcagatcgacttgtacgagtgcat
ggtgaccctgcagtgtggtgggtgtctcagtttgtcaaatacttgatccgcccacagcct
tggctagaaaaagaaatagaagaagccaccaagaagcttggcttcaaacatccagttatt
ggagtccatgtcagacgcacagacaaagtgggaacagaagctgccttccatcccattgaa
gagtacatggtgcatgttgaagaacattttcagcttcttgcacgcagaatgcaagtggac
aaaaaaagagtgtatttggccacagatgacccttctttattaaaggaggcaaaaacaaag
taccccaattatgaatttattagtgataactctatttcctggtcagctggactgcacaat
cgatacacagaaaattcacttcgtggagtgatcctggatatacattttctctctcaggca
gacttcctagtgtgtactttttcatcccaggtctgtcgagttgcttatgaaattatgcaa
acactacatcctgatgcctctgcaaacttccattctttagatgacatctactattttggg
ggccagaatgcccacaatcaaattgccatttatgctcaccaaccccgaactgcagatgaa
attcccatggaacctggagatatcattggtgtggctggaaatcattgggatggctattct
aaaggtgtcaacaggaaattgggaaggacgggcctatatccctcctacaaagttcgagag
aagatagaaacggtcaagtaccccacatatcctgaggctgagaaataa

  All links  
Disease (2)   
   OMIM (2)   
Gene (10)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (20)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (67)   
   RefSeq(nuc) (19)   
   GenBank (24)   
   EMBL (24)   
3D Structure (8)   
   PDB (8)   
Protein domain (5)   
   Pfam (5)   
All databases (112)   

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