KEGG   Homo sapiens (human): 253782
Entry
253782            CDS       T01001                                 
Symbol
CERS6, CERS5, LASS6
Name
(RefSeq) ceramide synthase 6
  KO
K23727  sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    253782 (CERS6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    253782 (CERS6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.291  sphingoid base N-palmitoyltransferase
     253782 (CERS6)
SSDB
Motif
Pfam: TRAM_LAG1_CLN8 Homeodomain DUF5931
Other DBs
NCBI-GeneID: 253782
NCBI-ProteinID: NP_982288
OMIM: 615336
HGNC: 23826
Ensembl: ENSG00000172292
UniProt: Q6ZMG9
Structure
Position
2:168456272..168775134
AA seq 384 aa
MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVA
KPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQR
RNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHY
YYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDS
ADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPS
WWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPH
TATTTNGTSGTNGYLLTGSCSMDD
NT seq 1155 nt   +upstreamnt  +downstreamnt
atggcagggatcttagcctggttctggaacgagaggttttggctcccgcacaatgtcacc
tgggcggacctgaagaacacggaggaggccaccttcccgcaggctgaggacctctatctc
gcttttcccctggccttctgtatcttcatggtgcggctcatcttcgagagatttgtagcc
aaaccgtgcgccatagccctcaacattcaggccaatggaccacaaattgctccgcccaat
gccattctggaaaaggtcttcactgcaattacaaagcatcctgatgaaaagagattggaa
ggcctctccaagcaactggactgggatgttcgaagcattcagcgctggtttcgacaaaga
cgcaatcaggagaagccaagcacgctgacgaggttctgtgagagcatgtggagattttca
ttttacctttatgtatttacctacggagtcagattcctgaaaaagaccccctggttgtgg
aatacgaggcattgctggtacaactacccctatcagccactcacaactgaccttcactac
tattacatcctggagctgtcgttttattggtctttgatgttttctcagttcactgatatc
aaaagaaaggactttggcattatgttcctgcaccaccttgtatctattttcttgattacc
ttttcatatgtcaacaatatggcccgagtaggaacgctggtcctttgtcttcatgattca
gctgatgctcttctggaggctgccaaaatggcaaattatgccaagtttcagaaaatgtgt
gatctcctgtttgttatgtttgccgtggtttttatcaccacacgactgggtatatttcct
ctctgggtgttaaataccacattatttgaaagctgggagatcgttggaccttacccttcc
tggtgggtttttaacctactgctattgctagtacaagggttgaactgcttctggtcttac
ttgattgtgaaaatagcttgcaaagctgtttcaagaggcaaggtgtccaaggatgatcga
agtgatattgagtctagctcagatgaggaggactcagaacctccgggaaagaatccccac
actgcgacaaccaccaatgggaccagtggtaccaacgggtatctcctgactggctcctgc
tccatggatgattaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (12)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (35)   
   RefSeq(nuc) (5)   
   GenBank (15)   
   EMBL (15)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (61)   

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KEGG   Homo sapiens (human): 91012
Entry
91012             CDS       T01001                                 
Symbol
CERS5, LASS5, Trh4
Name
(RefSeq) ceramide synthase 5
  KO
K23727  sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    91012 (CERS5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    91012 (CERS5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.291  sphingoid base N-palmitoyltransferase
     91012 (CERS5)
SSDB
Motif
Pfam: TRAM_LAG1_CLN8 Homeodomain
Other DBs
NCBI-GeneID: 91012
NCBI-ProteinID: NP_671723
OMIM: 615335
HGNC: 23749
Ensembl: ENSG00000139624
UniProt: Q8N5B7
Position
12:complement(50129289..50167369)
AA seq 392 aa
MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFV
RLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVR
KIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPF
QPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVG
TLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES
WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEED
VTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE
NT seq 1179 nt   +upstreamnt  +downstreamnt
atggcgacagcagcgcagggacccctaagcttgctgtggggctggctgtggagcgagcgc
ttctggctacccgagaacgtgagctgggctgatctggaggggccggccgacggctacggt
tacccccgcggccggcacatcctctcggtgttcccgctggcggcgggcatcttcttcgtg
aggctgctcttcgagcgatttattgccaaaccctgtgcactctgtattggcatcgaggac
agtggtccttatcaggcccaacccaatgccatccttgaaaaggtgttcatatctattacc
aagtatcctgataagaaaaggctggagggcctgtcaaagcagctggattggaatgtccga
aaaatccaatgctggtttcgccatcggaggaatcaggacaagcccccaacgcttactaaa
ttctgtgaaagcatgtggagattcacattttatttatgtatattctgctatggaattaga
tttctctggtcgtcaccttggttctgggacatccgacagtgctggcataactatccattt
cagcctctttcaagtgggctttatcactattatatcatggaattggccttctattggtcc
cttatgttttctcagtttacagacattaaaagaaaggacttcctgatcatgtttgtgcat
cacttggtcaccattgggcttatctccttctcctacatcaacaatatggttcgagtggga
actctgatcatgtgtctacatgatgtctcagacttcttgctggaggcagccaaactggcc
aattatgccaagtatcagcggctctgtgacaccctttttgtgatcttcagtgctgttttt
atggttacacgactaggaatctatccattctggattctgaacacgaccctctttgagagt
tgggagataatcgggccttatgcttcatggtggctcctcaatggcctgctgctgacccta
cagcttctgcatgtcatctggtcctacctaattgcacggattgctttgaaagccttgatc
aggggaaaggtatcgaaggatgatcgcagtgatgtggagagcagctcagaggaagaagat
gtgaccacctgcacaaaaagtccctgtgacagtagctccagcaatggtgccaatcgggtg
aatggtcacatgggaggcagctactgggctgaagagtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (13)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (48)   
   RefSeq(nuc) (24)   
   GenBank (12)   
   EMBL (12)   
Protein domain (2)   
   Pfam (2)   
All databases (84)   

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