KEGG   Homo sapiens (human): 254531
Entry
254531            CDS       T01001                                 

Gene name
LPCAT4, AGPAT7, AYTL3, LPAAT-eta, LPEAT2
Definition
(RefSeq) lysophosphatidylcholine acyltransferase 4
  KO
K13512  lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00564  Glycerophospholipid metabolism
hsa00565  Ether lipid metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    254531 (LPCAT4)
   00565 Ether lipid metabolism
    254531 (LPCAT4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    254531 (LPCAT4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.23  1-acylglycerophosphocholine O-acyltransferase
     254531 (LPCAT4)
    2.3.1.-  
     254531 (LPCAT4)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   254531 (LPCAT4)
SSDB
Motif
Pfam: Acyltransferase
Other DBs
NCBI-GeneID: 254531
NCBI-ProteinID: NP_705841
OMIM: 612039
HGNC: 30059
Ensembl: ENSG00000176454
Vega: OTTHUMG00000172349
Pharos: Q643R3(Tdark)
UniProt: Q643R3
Position
15q14
AA seq 524 aa
MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVLLAFIVLFL
LWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLQ
APVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRR
VVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTT
SWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNVQRVMAQALGIP
ATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYVDAGAEPGRSRMISQEEF
ARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAALDGGRSLEELTRLAFELFAEEQ
AEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSSQGLSLCQFQNFSLHDPLYG
KLFSTYLRPPHTSRGTSQTPNASSPGNPTALANGTVQAPKQKGD
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgagccagggaagtccgggggactgggcccccctagatcccacccccggacccccagca
tcccccaaccccttcgtgcatgagttacatctctctcgcctccagagggttaagttctgc
ctcctgggggcattgctggcccccatccgagtgcttctggcctttatcgtcctctttctc
ctctggccctttgcctggcttcaagtggccggtcttagtgaggagcagcttcaggagcca
attacaggatggaggaagactgtgtgccacaacggggtgctaggcctgagccgcctgctg
tttttcctgctgggcttcctccggattcgcgttcgtggccagcgagcctctcgccttcaa
gcccctgtccttgttgctgccccacactccactttctttgaccccattgttctgctgccc
tgtgacctgcccaaagttgtgtcccgagctgagaacctttccgttcctgtcattggagcc
cttcttcgattcaaccaagccatcctggtatcccggcatgacccggcttctcgacgcaga
gtggtggaggaggtccgaaggcgggccacctcaggaggcaagtggccgcaggtgctattc
tttcctgagggcacctgttccaacaagaaggctttgcttaagttcaaaccaggagccttc
atcgcaggggtgcctgtgcagcctgtcctcatccgctaccccaacagtctggacaccacc
agctgggcatggaggggtcctggagtactcaaagtcctctggctcacagcctctcagccc
tgcagcattgtggatgtggagttccttcctgtgtatcaccccagccctgaggagagcagg
gaccccaccctctatgccaacaatgttcagagggtcatggcacaggctctgggcattcca
gccaccgaatgtgagtttgtagggagcttacctgtgattgtggtgggccggctgaaggtg
gcgttggaaccacagctctgggaactgggaaaagtgcttcggaaggctgggctgtccgct
ggctatgtggacgctggggcagagccaggccggagtcgaatgatcagccaggaagagttt
gccaggcagctacagctctctgatcctcagacggtggctggtgcctttggctacttccag
caggataccaagggtttggtggacttccgagatgtggcccttgcactagcagctctggat
gggggcaggagcctggaagagctaactcgtctggcctttgagctctttgctgaagagcaa
gcagagggtcccaaccgcctgctgtacaaagacggcttcagcaccatcctgcacctgctg
ctgggttcaccccaccctgctgccacagctttgcatgctgagctgtgccaggcaggatcc
agccaaggcctctccctctgtcagttccagaacttctccctccatgacccactctatggg
aaactcttcagcacctacctgcgccccccacacacctctcgaggcacctcccagacacca
aatgcctcatccccaggcaaccccactgctctggccaatgggactgtgcaagcacccaag
cagaagggagactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (7)   
   GenBank (14)   
   EMBL (14)   
Protein domain (1)   
   Pfam (1)   
All databases (87)   

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KEGG   Homo sapiens (human): 54947
Entry
54947             CDS       T01001                                 

Gene name
LPCAT2, AGPAT11, AYTL1, LysoPAFAT
Definition
(RefSeq) lysophosphatidylcholine acyltransferase 2
  KO
K13510  lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00564  Glycerophospholipid metabolism
hsa00565  Ether lipid metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    54947 (LPCAT2)
   00565 Ether lipid metabolism
    54947 (LPCAT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    54947 (LPCAT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.23  1-acylglycerophosphocholine O-acyltransferase
     54947 (LPCAT2)
    2.3.1.67  1-alkylglycerophosphocholine O-acetyltransferase
     54947 (LPCAT2)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   54947 (LPCAT2)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_6 EF-hand_7 Acyltransferase EF-hand_5 EF-hand_8 EF-hand_4 IF2_N
Other DBs
NCBI-GeneID: 54947
NCBI-ProteinID: NP_060309
OMIM: 612040
HGNC: 26032
Ensembl: ENSG00000087253
Vega: OTTHUMG00000133238
Pharos: Q7L5N7(Tbio)
UniProt: Q7L5N7
Position
16q12.2
AA seq 544 aa
MSRCAQAAEVAATVPGAGVGNVGLRPPMVPRQASFFPPPVPNPFVQQTQIGSARRVQIVL
LGIILLPIRVLLVALILLLAWPFAAISTVCCPEKLTHPITGWRRKITQTALKFLGRAMFF
SMGFIVAVKGKIASPLEAPVFVAAPHSTFFDGIACVVAGLPSMVSRNENAQVPLIGRLLR
AVQPVLVSRVDPDSRKNTINEIIKRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPG
VPVQPVLLRYPNKLDTVTWTWQGYTFIQLCMLTFCQLFTKVEVEFMPVQVPNDEEKNDPV
LFANKVRNLMAEALGIPVTDHTYEDCRLMISAGQLTLPMEAGLVEFTKISRKLKLDWDGV
RKHLDEYASIASSSKGGRIGIEEFAKYLKLPVSDVLRQLFALFDRNHDGSIDFREYVIGL
AVLCNPSNTEEIIQVAFKLFDVDEDGYITEEEFSTILQASLGVPDLDVSGLFKEIAQGDS
ISYEEFKSFALKHPEYAKIFTTYLDLQTCHVFSLPKEVQTTPSTASNKVSPEKHEESTSD
KKDD
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgagccggtgcgcccaggcggcggaagtggcggccacagtgccaggtgccggcgtcggg
aacgtggggctgcggccgcccatggtgccccgtcaggcgtccttcttcccgccgccggtg
ccgaaccccttcgtgcagcagacgcagatcggctccgcgaggcgggtccagattgtcctt
cttgggattatcttgcttccaattcgtgtcttattggttgcgttaattttattacttgca
tggccatttgctgcaatttcaacagtatgctgtcctgaaaagctgacccacccaataact
ggttggaggaggaaaattactcaaacagctttgaaatttctgggtcgtgctatgttcttt
tcaatgggatttatagttgctgtaaaaggaaagattgcaagtcctttggaagcaccagtt
tttgttgctgcccctcattcaacattctttgatggaattgcctgtgttgtagctgggtta
ccttctatggtatctcgaaatgagaatgcacaagtccctctgattggcagactgttacgg
gctgtgcaaccagttttggtgtcccgtgtagatccggattcccgaaaaaacacaataaat
gaaataataaagcgaacaacatcaggaggagaatggccccagatactagttttcccagaa
ggtacttgtactaatcgttcctgtttgattacttttaaaccaggagccttcattccagga
gttccagtgcagccagtcctcctcagatacccaaacaagctggatactgtgacctggaca
tggcaaggatatacattcattcagctttgtatgcttactttctgccagctcttcacaaag
gtagaagttgagtttatgccagttcaagtaccaaatgatgaagaaaaaaatgatcctgtc
ctttttgccaataaagtccggaatttaatggcagaagctctgggaataccagtaacagat
catacctatgaagactgcagattgatgatttcagcaggacagctaacattgcctatggaa
gctgggctggtggaatttactaaaattagccgaaaattgaaattagattgggatggtgtt
cgtaagcatttggatgaatatgcatctattgcgagttcctcaaaaggaggaagaattgga
attgaagaattcgccaagtatttaaagttgcctgtttcagatgtcttgagacaacttttt
gcactctttgacaggaaccatgatggcagcattgacttccgagagtatgtgattggcctg
gctgtcttgtgcaacccttccaacacagaggagatcatccaggtggcatttaagctgttt
gacgttgatgaggatggctacataacggaggaagagttctccaccattctacaggcttcc
cttggagtgcctgaccttgatgtttctggtctcttcaaggaaatagcccaaggggactca
atttcctatgaggaatttaaaagttttgccttaaagcatccagaatatgctaagatattt
acaacatacctagacctccagacgtgccatgtgttttcattaccaaaagaagtccagaca
accccctccaccgccagtaataaagtcagccctgaaaagcatgaagagagtacctcagac
aaaaaagatgactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (26)   
   RefSeq(nuc) (4)   
   GenBank (11)   
   EMBL (11)   
Protein domain (8)   
   Pfam (8)   
All databases (82)   

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KEGG   Homo sapiens (human): 79888
Entry
79888             CDS       T01001                                 

Gene name
LPCAT1, AGPAT10, AGPAT9, AYTL2, LPCAT-1, PFAAP3, lpcat, lysoPAFAT
Definition
(RefSeq) lysophosphatidylcholine acyltransferase 1
  KO
K13510  lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00564  Glycerophospholipid metabolism
hsa00565  Ether lipid metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    79888 (LPCAT1)
   00565 Ether lipid metabolism
    79888 (LPCAT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    79888 (LPCAT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.23  1-acylglycerophosphocholine O-acyltransferase
     79888 (LPCAT1)
    2.3.1.67  1-alkylglycerophosphocholine O-acetyltransferase
     79888 (LPCAT1)
Lipid biosynthesis proteins [BR:hsa01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   79888 (LPCAT1)
SSDB
Motif
Pfam: Acyltransferase EF-hand_8 EF-hand_1 EF-hand_6 EF-hand_7 IF2_N
Other DBs
NCBI-GeneID: 79888
NCBI-ProteinID: NP_079106
OMIM: 610472
HGNC: 25718
Ensembl: ENSG00000153395
Vega: OTTHUMG00000131017
Pharos: Q8NF37(Tbio)
UniProt: Q8NF37
Position
5p15.33
AA seq 534 aa
MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLV
AAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVVDFLLKAIMRTMWFAGGFHRVAVKGR
QALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQ
DSRRKTVEEIKRRAQSNGKWPQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPN
KLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAE
ALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERAR
MKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDT
IQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFA
EMYPAFAEEYLYPDQTHFESCAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgaggctgcggggatgcggaccccgggccgcccctgcctccagcgcaggggccagcgac
gctcggctgctggcgcccccggggcggaaccccttcgtgcacgagctgcgcctcagcgcc
ctgcagaaggcccaggtggccctcatgacactgacgctcttcccggtccggctcctggtt
gccgctgccatgatgctgctggcctggcccctcgcacttgtcgcatccctgggctctgcg
gagaaggaacccgagcagcccccggccctgtggaggaaggttgtggacttcctgctgaag
gccatcatgcgcaccatgtggttcgccggcggcttccaccgggtggccgtgaaggggcgg
caggcgctgcccaccgaggcggccatcctcacgctcgcgcctcactcgtcctacttcgac
gccatccctgtgaccatgacgatgtcctccatcgtgatgaaggcagagagcagagacatc
ccgatctggggaactctgatccagtatatacggcctgtgttcgtgtcccggtcagaccag
gattctcgcaggaaaacagtagaagaaatcaagagacgggcgcagtccaacggaaagtgg
ccacagataatgatttttccagaaggaacttgtacaaacaggacctgcctaattaccttc
aaacctggtgcattcatccctggagcgcccgtccagcctgtggttttacgatatccaaat
aaactggacaccatcacatggacgtggcaaggacctggagcgctggaaatcctgtggctc
acgctgtgtcagtttcacaaccaagtggaaatcgagttccttcctgtgtacagcccttct
gaggaggagaagaggaaccccgcgctgtatgccagcaacgtgcggcgagtcatggccgag
gccttgggtgtctccgtgactgactacacgttcgaggactgccagctggccctggcggaa
ggacagctccgtctccccgctgacacttgccttttagaatttgccaggctcgtgcggggc
ctcgggctaaaaccagaaaagcttgaaaaagatctggacagatactcagaaagagccagg
atgaagggaggagagaagataggtattgcggagtttgccgcctccctggaagtccccgtt
tctgacttgctggaagacatgttttcactgttcgacgagagcggcagcggcgaggtggac
ctgcgagagtgtgtggttgccctgtctgtcgtctgccggccggcccggaccctggacacc
atccagctggctttcaagatgtacggagcgcaagaggacggcagcgtcggcgaaggtgac
ctgtcctgcatcctcaagacggccctgggggtggcagagctcaccgtgaccgacctattc
cgagccattgaccaagaggagaaggggaagatcacattcgctgacttccacaggtttgca
gaaatgtaccctgccttcgcagaggaatacctgtacccggatcagacacatttcgaaagc
tgtgcagagacctcacctgcgccaatcccaaacggcttctgtgccgatttcagcccggaa
aactcagacgctgggcggaagcctgttcgcaagaagctggattag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (37)   
   RefSeq(nuc) (5)   
   GenBank (16)   
   EMBL (16)   
Protein domain (6)   
   Pfam (6)   
All databases (98)   

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