KEGG   Homo sapiens (human): 2569
Entry
2569              CDS       T01001                                 
Symbol
GABRR1
Name
(RefSeq) gamma-aminobutyric acid receptor subunit rho-1 isoform a precursor
  KO
K05190  gamma-aminobutyric acid receptor subunit rho
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04082  Neuroactive ligand signaling
hsa04519  Cadherin signaling
hsa04723  Retrograde endocannabinoid signaling
hsa04727  GABAergic synapse
hsa05032  Morphine addiction
hsa05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2569 (GABRR1)
   04082 Neuroactive ligand signaling
    2569 (GABRR1)
   04519 Cadherin signaling
    2569 (GABRR1)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    2569 (GABRR1)
   04723 Retrograde endocannabinoid signaling
    2569 (GABRR1)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    2569 (GABRR1)
   05033 Nicotine addiction
    2569 (GABRR1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    2569 (GABRR1)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  GABA-A
   2569 (GABRR1)
SSDB
Motif
Pfam: Neur_chan_LBD Neur_chan_memb
Other DBs
NCBI-GeneID: 2569
NCBI-ProteinID: NP_002033
OMIM: 137161
HGNC: 4090
Ensembl: ENSP00000412673.2
UniProt: P24046
Structure
Position
6:complement(89177504..89231288)
AA seq 479 aa
MLAVPNMRFGIFLLWWGWVLATESRMHWPGREVHEMSKKGRPQRQRREVHEDAHKQVSPI
LRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVGVDVQVESLDSISEVDMDFTM
TLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRV
QPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTD
ERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSW
VSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVL
EYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGNYSDGEVNDLDNYMPENGEKP
DRMMVQLTLASERSSPQRKSQRSSYVSMRIDTHAIDKYSRIIFPAAYILFNLIYWSIFS
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgttggctgtcccaaatatgagatttggcatctttcttttgtggtggggatgggttttg
gccactgaaagcagaatgcactggcccggaagagaagtccacgagatgtctaagaaaggc
aggccccaaagacaaagacgagaagtacatgaagatgcccacaagcaagtcagcccaatt
ctgagacgaagtcctgacatcaccaaatcgcctctgacaaagtcagaacagcttctgagg
atagatgaccatgatttcagcatgaggcctggctttggaggccctgccattcctgttggt
gtggatgtgcaggtggagagtttggatagcatctcagaggttgacatggactttacgatg
accctctacctgaggcactactggaaggacgagaggctgtcttttccaagcaccaacaac
ctcagcatgacgtttgacggccggctggtcaagaagatctgggtccctgacatgtttttc
gtgcactccaaacgctccttcatccacgacaccaccacagacaacgtcatgttgcgggtc
cagcctgatgggaaagtgctctatagtctcagggttacagtaactgcaatgtgcaacatg
gacttcagccgatttcccttggacacacaaacgtgctctcttgaaattgaaagctatgcc
tatacagaagatgacctcatgctgtactggaaaaagggcaatgactccttaaagacagat
gaacggatctcactctcccagttcctcattcaggaattccacaccaccaccaaactggct
ttctacagcagcacaggctggtacaaccgtctctacattaatttcacgttgcgtcgccac
atcttcttcttcttgctccaaacttatttccccgctaccctgatggtcatgctgtcctgg
gtgtccttctggatcgaccgcagagccgtgcctgccagagtccccttaggtatcacaacg
gtgctgaccatgtccaccatcatcacgggcgtgaatgcctccatgccgcgcgtctcctac
atcaaggccgtggacatctacctctgggtcagctttgtgttcgtgttcctctcggtgctg
gagtatgcggccgtcaactacctgaccactgtgcaggagaggaaggaacagaagctgcgg
gagaagcttccctgcaccagcggattacctccgccccgcactgcgatgctggacggcaac
tacagtgatggggaggtgaatgacctggacaactacatgccagagaatggagagaagccc
gacaggatgatggtgcagctgaccctggcctcagagaggagctccccacagaggaaaagt
cagagaagcagctatgtgagcatgagaatcgacacccacgccattgataaatactccagg
atcatctttccagcagcatacattttattcaatttaatatactggtctattttctcctag

  All links  
Disease (1)   
   OMIM (1)   
Gene (9)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (23)   
   RefSeq(nuc) (7)   
   GenBank (8)   
   EMBL (8)   
3D Structure (26)   
   PDB (26)   
Protein domain (2)   
   Pfam (2)   
All databases (70)   

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