KEGG   Homo sapiens (human): 25778
Entry
25778             CDS       T01001                                 
Symbol
DSTYK, CAKUT1, DustyPK, HDCMD38P, RHDNS1, RIP5, RIPK5, SPG23
Name
(RefSeq) dual serine/threonine and tyrosine protein kinase
  KO
K16288  dual serine/threonine and tyrosine protein kinase [EC:2.7.12.1]
Organism
hsa  Homo sapiens (human)
Disease
H00266  Hereditary spastic paraplegia
H01867  Congenital anomalies of kidney and urinary tract
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    25778 (DSTYK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.1  dual-specificity kinase
     25778 (DSTYK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  Other
   25778 (DSTYK)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Haspin_kinase Kinase-like Kdo Microp_apicomplexa_17
Other DBs
NCBI-GeneID: 25778
NCBI-ProteinID: NP_056190
OMIM: 612666
HGNC: 29043
Ensembl: ENSG00000133059
UniProt: Q6XUX3
Position
1:complement(205142505..205211702)
AA seq 929 aa
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN
HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD
CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH
QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL
VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER
SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK
ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI
VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL
ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM
LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF
AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR
GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY
NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL
KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWY
ICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLG
IVQPMLQGIMNRLCKSNSEQPNRGLDDST
NT seq 2790 nt   +upstreamnt  +downstreamnt
atggagggcgacggggtgccatggggcagcgagcccgtctcgggtcccggccccggcggc
ggcggaatgatccgcgagctgtgccggggcttcggccgctaccgccgctacctgggacgg
ctgcgacagaacctgcgcgagacccagaagttcttccgcgacatcaagtgctcccacaac
cacacttgtctctcctccctcacgggcggcggcggggccgagcgcggccctgcaggcgat
gtcgccgaaaccgggctgcaggcgggccaactgagctgcatttccttcccacctaaggaa
gagaagtacctccagcagattgtggactgcctcccttgcatactgatcctcggccaggat
tgtaacgtcaagtgccagctgttgaatctgctgttgggggtgcaggtgcttcccaccacc
aagctgggcagtgaggagagctgtaagcttcggcgcctccgcttcacctatgggactcag
actcgggtcagcctggcgctccctggacagtatgaactagtgcacacgctggttgctcat
cagggcaactgggagaccatccctgaggaggatctggaggtccaagagaacaatgaggat
gctgctcatgttttagcggaactggaggtaacgatgcaccatgctctcttacaggaagtg
gacgttgtggtagcaccatgccaaggcctccggcccacagtggatgttctgggtgacttg
gtgaatgatttcttgcctgtgataacctatgcactccacaaagatgaactctctgagagg
gatgagcaagagcttcaggaaatccgaaagtatttctcctttcctgtattctttttcaaa
gtgccgaaactgggctcggagataatagactcctcaaccaggagaatggagagcgaaaga
tcaccgctttatcgccagctaattgacctgggctatctgagcagcagtcactggaactgt
ggggctcctggccaggatactaaagctcagagcatgttggtggaacagagtgaaaagctg
agacacttgagcacattttctcaccaggtgttacagactcgcctggtggatgcagccaag
gccctgaacctggtgcactgccactgccttgacatctttattaaccaggcatttgacatg
cagcgggacctgcagatcactcccaaacgtctggaatatactcgaaaaaaggagaatgag
ttgtatgaatcattgatgaatattgccaaccgaaagcaggaggaaatgaaggatatgatt
gttgagacacttaataccatgaaggaggaacttctggatgatgctactaacatggagttt
aaagacgtcattgtccctgagaatggagaaccagtaggcaccagagagatcaaatgctgc
atccgacagatccaggaactcatcatctcccgacttaatcaggcagtggctaataagctg
atcagctcagtggattacctgagggaaagcttcgtcggaaccctggaacgatgtctgcag
agcctggagaagtctcaggatgtctcagttcacatcaccagtaattatctcaaacagatc
ttaaatgctgcctatcatgttgaagtcacgtttcactcagggtcgtcagttacaaggatg
ctatgggagcaaatcaaacagatcatccagcgcatcacatgggtgagcccacctgccatc
actctggaatggaagaggaaggtggcccaggaagccattgagagcctcagcgcctccaaa
ttggctaagagcatttgcagccaattccggactcggctcaatagttcccacgaggctttt
gcagcctccttgcggcagctggaagctggccactcaggccggttagagaaaacggaagat
ctatggctgagggttcggaaagatcatgctccccgcctggcccgcctttctctggaaagc
tgttctttacaggatgtcttgcttcatcgtaaacctaaactgggacaggaactgggccgg
ggccagtatggtgtggtatacctgtgtgacaactggggaggacacttcccttgtgccctc
aaatcagttgtccctccagatgagaagcactggaatgatctggctttggaatttcactat
atgaggtctctgccgaagcatgagcgattggtggatctccatggttcagtcattgactac
aactatggtggtggctccagcattgctgtgctcctcattatggagcggctacaccgggat
ctctacacagggctgaaggctgggctgaccctggagacacgtttgcagatagcactagat
gtggtggagggaatccgcttcctgcacagccagggacttgtccatcgtgatatcaaactg
aaaaatgtgctgctggataagcagaaccgtgccaagatcactgacttaggattctgcaag
ccagaggccatgatgtcaggcagcattgtggggacaccaatccatatggcccctgaactt
ttcacagggaagtacgataattccgtggatgtctacgcttttggaattcttttctggtat
atctgctcaggctctgtcaagctccctgaggcatttgagaggtgtgctagcaaagaccat
ctctggaacaatgtgcggaggggggctcgcccagaacgtcttcctgtgtttgatgaggag
tgctggcagttgatggaagcctgttgggatggcgaccccttgaagaggcctctcttgggc
attgtccagcccatgctccagggcatcatgaatcggctctgcaagtccaattctgagcag
ccaaacagaggactagatgattctacttga

  All links  
Disease (3)   
   OMIM (3)   
Gene (29)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (16)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (64)   
   RefSeq(nuc) (14)   
   GenBank (25)   
   EMBL (25)   
Protein domain (7)   
   Pfam (7)   
All databases (119)   

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