KEGG   Homo sapiens (human): 2580Help
Entry
2580              CDS       T01001                                 

Gene name
GAK, DNAJ26, DNAJC26
Definition
(RefSeq) cyclin G associated kinase
  KO
K08855  cyclin G-associated kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2580 (GAK)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2580 (GAK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     2580 (GAK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  NAK family [OT]
   2580 (GAK)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    2580 (GAK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase PTEN_C2 Pkinase_Tyr DnaJ Kinase-like Haspin_kinase Seadorna_VP7 APH RelB_N DSPc
Motif
Other DBs
NCBI-GeneID: 2580
NCBI-ProteinID: NP_005246
OMIM: 602052
HGNC: 4113
Ensembl: ENSG00000178950
Vega: OTTHUMG00000088301
Pharos: O14976(Tchem)
UniProt: O14976
Structure
PDB: 

Position
4p16.3
AA seq 1311 aa AA seqDB search
MSLLQSALDFLAGPGSLGGASGRDQSDFVGQTVELGELRLRVRRVLAEGGFAFVYEAQDV
GSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFL
LLTELCKGQLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLL
LSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPI
GEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNP
EERLSIAEVVHQLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPPPPVGPAGSGYSG
GLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDLDISYITSRIAVM
SFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFHNRVSECGWAARRAP
HLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFS
MKRCPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVVMTPVPLFSKQRSGCRPFCE
VYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVLIVIYHARSTLGGRLQAKMA
SMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQVNLEVEVEPRDRPSREAP
PWENSSMRGLNPKILFSSREEQQDILSKFGKPELPRQPGSTAQYDAGAGSPEAEPTDSDS
PPSSSADASRFLHTLDWQEEKEAETGAENASSKESESALMEDRDESEVSDEGGSPISSEG
QEPRADPEPPGLAAGLVQQDLVFEVETPAVLPEPVPQEDGVDLLGLHSEVGAGPAVPPQA
CKAPSSNTDLLSCLLGPPEAASQGPPEDLLSEDPLLLASPAPPLSVQSTPRGGPPAAADP
FGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPPSFPSAHSAPPPSCSADFLHLGDLPGE
PSKMTASSSNPDLLGGWAAWTETAASAVAPTPATEGPLFSPGGQPAPCGSQASWTKSQNP
DPFADLGDLSSGLQGSPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKPPPK
ACTQPRPNYASNFSVIGAREERGVRAPSFAQKPKVSENDFEDLLSNQGFSSRSDKKGPKT
IAEMRKQDLAKDTDPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAP
EQVKKHYRRAVLAVHPDKAAGQPYEQHAKMIFMELNDAWSEFENQGSRPLF
NT seq 3936 nt NT seq  +upstreamnt  +downstreamnt
atgtcgctgctgcagtcggcgctcgacttcttggcgggtccaggctccctgggcggtgct
tccggccgcgaccagagtgacttcgtggggcagacggtggaactgggcgagctgcggctg
cgggtgcggcgggtcctggccgaaggagggtttgcatttgtgtatgaagctcaagatgtg
gggagtggcagagagtatgcattaaagaggctattatccaatgaagaggaaaagaacaga
gccatcattcaagaagtttgcttcatgaaaaagctttccggccacccgaacattgtccag
ttttgttctgcagcgtctataggaaaagaggagtcagacacggggcaggctgagttcctc
ttgctcacagagctctgtaaagggcagctggtggaatttttgaagaaaatggaatctcga
ggccccctttcgtgcgacacggttctgaagatcttctaccagacgtgccgcgccgtgcag
cacatgcaccggcagaagccgcccatcatccacagggacctcaaggttgagaacttgttg
cttagtaaccaagggaccattaagctgtgtgactttggcagtgccacgaccatctcgcac
taccctgactacagctggagcgcccagaggcgagccctggtggaggaagagatcacgagg
aatacaacaccaatgtatagaacaccagaaatcatagacttgtattccaacttcccgatc
ggcgagaagcaggatatctgggccctgggctgcatcttgtacctgctgtgcttccggcag
cacccttttgaggatggagcgaaacttcgaatagtcaatgggaagtactcgatccccccg
cacgacacgcagtacacggtcttccacagcctcatccgcgccatgctgcaggtgaacccg
gaggagcggctgtccatcgccgaggtggtgcaccagctgcaggagatcgcggccgcccgc
aacgtgaaccccaagtctcccatcacagagctcctggagcagaatggaggctacgggagc
gccacactgtcccgagggccaccccctcccgtgggccccgctggcagtggctacagtgga
ggcctggcgctggcggagtacgaccagccgtatggcggcttcctggacattctgcggggt
gggacagagcggctcttcaccaacctcaaggacacctcctccaaggtcatccagtccgtc
gctaattatgcaaagggtgacctggacatatcttacatcacatccagaattgcagtgatg
tcattcccagcagaaggtgtggagtcagcgctcaaaaacaacatcgaagatgtgcggttg
ttcctggactccaagcacccagggcactatgccgtctacaacctgtccccgaggacctac
cggccctccaggttccacaaccgggtctccgagtgtggctgggcagcacggcgggcccca
cacctgcacaccctgtacaacatctgcaggaacatgcacgcctggctgcggcaggaccac
aagaacgtctgcgtcgtgcactgcatggacgggagagccgcgtctgctgtggccgtctgc
tccttcctgtgcttctgccgtctcttcagcaccgcggaggccgccgtgtacatgttcagc
atgaagcgctgcccaccaggcatctggccatcccacaaaaggtacatcgagtacatgtgt
gacatggtggcggaggagcccatcacaccccacagcaagcccatcctggtgagggccgtg
gtcatgacacccgtgccgctgttcagcaagcagaggagcggctgcaggcccttctgcgag
gtctacgtgggggacgagcgtgtggccagcacctcccaggagtacgacaagatgcgggac
tttaagattgaagatggcaaagcggtgattcccctgggcgtcacggtgcaaggagacgtg
ctcatcgtcatctatcacgcccggtccactctgggcggccggctgcaggccaagatggca
tccatgaagatgttccagattcagttccacacggggtttgtgcctcggaacgccaccact
gtgaaatttgccaagtatgacctggacgcgtgtgacattcaagaaaaatacccggattta
tttcaagtgaacctggaagtggaggtggagcccagggacaggccgagccgggaagcccca
ccatgggagaactcgagcatgagggggctgaaccccaaaatcctgttttccagccgggag
gagcagcaagacattctgtctaagtttgggaagccggagcttccccggcagcctggctcc
acggctcagtatgatgctggggcagggtccccggaagccgaacccacagactctgactca
ccgccaagcagcagcgcggacgccagtcgcttcctgcacacgctggactggcaggaagag
aaggaggcagagactggtgcagaaaatgcctcttccaaggagagcgagtctgccctgatg
gaggacagagacgagagtgaggtgtcagatgaagggggatccccgatctccagcgagggc
caggaacccagggccgacccagagccccccggcctggcagcagggctggtgcagcaggac
ttggtttttgaggtggagacaccggctgtgctgccagagcctgtgccacaggaagacggg
gtcgacctcctgggcctgcactccgaggtgggcgcagggccagctgtacccccgcaggcc
tgcaaggccccctccagcaacaccgacctgctcagctgcctccttgggccccctgaggcc
gcctcccaggggcccccggaggatctgctcagcgaggacccgctgctcctggcaagcccg
gcccctcccctgagcgtgcagagcaccccaagaggagggccccctgccgctgctgacccc
tttggcccgcttctgccgtcttcaggcaacaactcccagccctgctccaatcctgatctc
ttcggcgaatttctcaattcggactctgtgaccgtcccaccatccttcccgtctgcccac
agtgctccgcccccatcctgcagcgccgacttcctgcacctgggggatctgccaggagag
cccagcaagatgacagcctcgtccagcaacccagacctgctgggaggatgggctgcctgg
accgagactgcagcatcggcagtggcccccacgccagccacagaaggccccctcttctct
cctggaggtcagccggccccttgtggctctcaggccagctggaccaagtctcagaacccg
gacccatttgctgaccttggcgacctcagctccggcctccaaggctcaccagctggattc
cctcctgggggcttcattcccaaaacggccaccacgcccaaaggcagcagctcctggcag
acaagtcggccgccagcccagggcgcctcatggccccctcaggccaagccgccccccaaa
gcctgcacacagccaaggcctaactatgcctcgaacttcagtgtgatcggggcgcgggag
gagcggggggtccgcgcacccagctttgctcaaaagccaaaagtctctgagaacgacttt
gaagatctgttgtccaatcaaggcttctcctccaggtctgacaagaaagggccaaagacc
attgcagagatgaggaagcaggacctggctaaagacacggacccactcaagctgaagctc
ctggactggattgagggcaaggagcggaacatccgggccctgctgtccacgctgcacaca
gtgctgtgggacggggagagccgctggacgcccgtgggcatggccgacctggtggctccg
gagcaagtgaagaagcactatcgccgcgcggtgctggctgtgcaccccgacaaggctgcg
gggcagccgtacgagcagcacgccaagatgatcttcatggagctgaatgacgcctggtcg
gagtttgagaaccagggctcccggcccctcttctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (20)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (59)   
   RefSeq(nuc) (19)   
   GenBank (20)   
   EMBL (20)   
Protein domain (10)   
   Pfam (10)   
All databases (132)   

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