KEGG   Homo sapiens (human): 2580
Entry
2580              CDS       T01001                                 
Symbol
GAK, DNAJ26, DNAJC26
Name
(RefSeq) cyclin G associated kinase
  KO
K08855  cyclin G-associated kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2580 (GAK)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2580 (GAK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     2580 (GAK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  NAK family [OT]
   2580 (GAK)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    2580 (GAK)
SSDB
Motif
Pfam: Pkinase PTEN_C2 PK_Tyr_Ser-Thr DnaJ Kinase-like Haspin_kinase ABC1 APH Seadorna_VP7 DSPc
Other DBs
NCBI-GeneID: 2580
NCBI-ProteinID: NP_005246
OMIM: 602052
HGNC: 4113
Ensembl: ENSG00000178950
Pharos: O14976(Tchem)
UniProt: O14976
Structure
Position
4:complement(849277..932316)
AA seq 1311 aa
MSLLQSALDFLAGPGSLGGASGRDQSDFVGQTVELGELRLRVRRVLAEGGFAFVYEAQDV
GSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFL
LLTELCKGQLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLL
LSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPI
GEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNP
EERLSIAEVVHQLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPPPPVGPAGSGYSG
GLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDLDISYITSRIAVM
SFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFHNRVSECGWAARRAP
HLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFS
MKRCPPGIWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVVMTPVPLFSKQRSGCRPFCE
VYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVLIVIYHARSTLGGRLQAKMA
SMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQVNLEVEVEPRDRPSREAP
PWENSSMRGLNPKILFSSREEQQDILSKFGKPELPRQPGSTAQYDAGAGSPEAEPTDSDS
PPSSSADASRFLHTLDWQEEKEAETGAENASSKESESALMEDRDESEVSDEGGSPISSEG
QEPRADPEPPGLAAGLVQQDLVFEVETPAVLPEPVPQEDGVDLLGLHSEVGAGPAVPPQA
CKAPSSNTDLLSCLLGPPEAASQGPPEDLLSEDPLLLASPAPPLSVQSTPRGGPPAAADP
FGPLLPSSGNNSQPCSNPDLFGEFLNSDSVTVPPSFPSAHSAPPPSCSADFLHLGDLPGE
PSKMTASSSNPDLLGGWAAWTETAASAVAPTPATEGPLFSPGGQPAPCGSQASWTKSQNP
DPFADLGDLSSGLQGSPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKPPPK
ACTQPRPNYASNFSVIGAREERGVRAPSFAQKPKVSENDFEDLLSNQGFSSRSDKKGPKT
IAEMRKQDLAKDTDPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAP
EQVKKHYRRAVLAVHPDKAAGQPYEQHAKMIFMELNDAWSEFENQGSRPLF
NT seq 3936 nt   +upstreamnt  +downstreamnt
atgtcgctgctgcagtcggcgctcgacttcttggcgggtccaggctccctgggcggtgct
tccggccgcgaccagagtgacttcgtggggcagacggtggaactgggcgagctgcggctg
cgggtgcggcgggtcctggccgaaggagggtttgcatttgtgtatgaagctcaagatgtg
gggagtggcagagagtatgcattaaagaggctattatccaatgaagaggaaaagaacaga
gccatcattcaagaagtttgcttcatgaaaaagctttccggccacccgaacattgtccag
ttttgttctgcagcgtctataggaaaagaggagtcagacacggggcaggctgagttcctc
ttgctcacagagctctgtaaagggcagctggtggaatttttgaagaaaatggaatctcga
ggccccctttcgtgcgacacggttctgaagatcttctaccagacgtgccgcgccgtgcag
cacatgcaccggcagaagccgcccatcatccacagggacctcaaggttgagaacttgttg
cttagtaaccaagggaccattaagctgtgtgactttggcagtgccacgaccatctcgcac
taccctgactacagctggagcgcccagaggcgagccctggtggaggaagagatcacgagg
aatacaacaccaatgtatagaacaccagaaatcatagacttgtattccaacttcccgatc
ggcgagaagcaggatatctgggccctgggctgcatcttgtacctgctgtgcttccggcag
cacccttttgaggatggagcgaaacttcgaatagtcaatgggaagtactcgatccccccg
cacgacacgcagtacacggtcttccacagcctcatccgcgccatgctgcaggtgaacccg
gaggagcggctgtccatcgccgaggtggtgcaccagctgcaggagatcgcggccgcccgc
aacgtgaaccccaagtctcccatcacagagctcctggagcagaatggaggctacgggagc
gccacactgtcccgagggccaccccctcccgtgggccccgctggcagtggctacagtgga
ggcctggcgctggcggagtacgaccagccgtatggcggcttcctggacattctgcggggt
gggacagagcggctcttcaccaacctcaaggacacctcctccaaggtcatccagtccgtc
gctaattatgcaaagggtgacctggacatatcttacatcacatccagaattgcagtgatg
tcattcccagcagaaggtgtggagtcagcgctcaaaaacaacatcgaagatgtgcggttg
ttcctggactccaagcacccagggcactatgccgtctacaacctgtccccgaggacctac
cggccctccaggttccacaaccgggtctccgagtgtggctgggcagcacggcgggcccca
cacctgcacaccctgtacaacatctgcaggaacatgcacgcctggctgcggcaggaccac
aagaacgtctgcgtcgtgcactgcatggacgggagagccgcgtctgctgtggccgtctgc
tccttcctgtgcttctgccgtctcttcagcaccgcggaggccgccgtgtacatgttcagc
atgaagcgctgcccaccaggcatctggccatcccacaaaaggtacatcgagtacatgtgt
gacatggtggcggaggagcccatcacaccccacagcaagcccatcctggtgagggccgtg
gtcatgacacccgtgccgctgttcagcaagcagaggagcggctgcaggcccttctgcgag
gtctacgtgggggacgagcgtgtggccagcacctcccaggagtacgacaagatgcgggac
tttaagattgaagatggcaaagcggtgattcccctgggcgtcacggtgcaaggagacgtg
ctcatcgtcatctatcacgcccggtccactctgggcggccggctgcaggccaagatggca
tccatgaagatgttccagattcagttccacacggggtttgtgcctcggaacgccaccact
gtgaaatttgccaagtatgacctggacgcgtgtgacattcaagaaaaatacccggattta
tttcaagtgaacctggaagtggaggtggagcccagggacaggccgagccgggaagcccca
ccatgggagaactcgagcatgagggggctgaaccccaaaatcctgttttccagccgggag
gagcagcaagacattctgtctaagtttgggaagccggagcttccccggcagcctggctcc
acggctcagtatgatgctggggcagggtccccggaagccgaacccacagactctgactca
ccgccaagcagcagcgcggacgccagtcgcttcctgcacacgctggactggcaggaagag
aaggaggcagagactggtgcagaaaatgcctcttccaaggagagcgagtctgccctgatg
gaggacagagacgagagtgaggtgtcagatgaagggggatccccgatctccagcgagggc
caggaacccagggccgacccagagccccccggcctggcagcagggctggtgcagcaggac
ttggtttttgaggtggagacaccggctgtgctgccagagcctgtgccacaggaagacggg
gtcgacctcctgggcctgcactccgaggtgggcgcagggccagctgtacccccgcaggcc
tgcaaggccccctccagcaacaccgacctgctcagctgcctccttgggccccctgaggcc
gcctcccaggggcccccggaggatctgctcagcgaggacccgctgctcctggcaagcccg
gcccctcccctgagcgtgcagagcaccccaagaggagggccccctgccgctgctgacccc
tttggcccgcttctgccgtcttcaggcaacaactcccagccctgctccaatcctgatctc
ttcggcgaatttctcaattcggactctgtgaccgtcccaccatccttcccgtctgcccac
agtgctccgcccccatcctgcagcgccgacttcctgcacctgggggatctgccaggagag
cccagcaagatgacagcctcgtccagcaacccagacctgctgggaggatgggctgcctgg
accgagactgcagcatcggcagtggcccccacgccagccacagaaggccccctcttctct
cctggaggtcagccggccccttgtggctctcaggccagctggaccaagtctcagaacccg
gacccatttgctgaccttggcgacctcagctccggcctccaaggctcaccagctggattc
cctcctgggggcttcattcccaaaacggccaccacgcccaaaggcagcagctcctggcag
acaagtcggccgccagcccagggcgcctcatggccccctcaggccaagccgccccccaaa
gcctgcacacagccaaggcctaactatgcctcgaacttcagtgtgatcggggcgcgggag
gagcggggggtccgcgcacccagctttgctcaaaagccaaaagtctctgagaacgacttt
gaagatctgttgtccaatcaaggcttctcctccaggtctgacaagaaagggccaaagacc
attgcagagatgaggaagcaggacctggctaaagacacggacccactcaagctgaagctc
ctggactggattgagggcaaggagcggaacatccgggccctgctgtccacgctgcacaca
gtgctgtgggacggggagagccgctggacgcccgtgggcatggccgacctggtggctccg
gagcaagtgaagaagcactatcgccgcgcggtgctggctgtgcaccccgacaaggctgcg
gggcagccgtacgagcagcacgccaagatgatcttcatggagctgaatgacgcctggtcg
gagtttgagaaccagggctcccggcccctcttctga

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (50)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (48)   
DNA sequence (89)   
   RefSeq(nuc) (49)   
   GenBank (20)   
   EMBL (20)   
3D Structure (7)   
   PDB (7)   
Protein domain (10)   
   Pfam (10)   
All databases (198)   

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