KEGG   Homo sapiens (human): 25820
Entry
25820             CDS       T01001                                 
Symbol
ARIH1, ARI, HARI, HHARI, UBCH7BP
Name
(RefSeq) ariadne RBR E3 ubiquitin protein ligase 1
  KO
K11968  ariadne-1 [EC:2.3.2.31]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
Network
nt06536  Mitophagy
  Element
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    25820 (ARIH1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    25820 (ARIH1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.31  RBR-type E3 ubiquitin transferase
     25820 (ARIH1)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   RBR proteins
    25820 (ARIH1)
SSDB
Motif
Pfam: IBR ARI1_UBAl IBR_1 IBR_2 Ariadne zf-C3HC4_2 zf-C3HC4 zf-RING_5 zf-RING_14 zf-RING_2 zf-C3HC4_4 zf-RING_UBOX
Other DBs
NCBI-GeneID: 25820
NCBI-ProteinID: NP_005735
OMIM: 605624
HGNC: 689
Ensembl: ENSG00000166233
Pharos: Q9Y4X5(Tbio)
UniProt: Q9Y4X5
Structure
Position
15:72474330..72602987
AA seq 557 aa
MDSDEGYNYEFDEDEECSEEDSGAEEEEDEDDDEPDDDTLDLGEVELVEPGLGVGGERDG
LLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREV
NEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSS
AQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILV
DDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCG
RQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHM
VCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNR
YMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAF
YLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLL
QHVHEGYEKDLWEYIED
NT seq 1674 nt   +upstreamnt  +downstreamnt
atggactcggacgagggctacaactacgagttcgacgaggacgaggagtgcagtgaggag
gacagcggcgccgaggaggaggaggacgaagacgacgacgagccggacgatgataccctg
gatctgggcgaggtggagctggtggagcccgggctgggcgtcggcggggagcgggacgga
ctgctgtgcggggagacgggcggtggcggcggcagcgctctggggcccggcggtggcggc
ggcggcggcggcggcggtggtggtggcgggccggggcatgagcaggaggaggattaccgc
tacgaggtgctcacggccgagcagattctacaacacatggtggaatgtatccgggaggtc
aacgaggtcatccagaatccagcaactatcacaagaatactccttagccacttcaattgg
gataaagagaagctaatggaaaggtactttgatggaaacctggagaagctctttgctgag
tgtcatgtaattaatccaagtaaaaagtctcgaacacgccagatgaatacaaggtcatca
gcacaggatatgccttgtcagatctgctacttgaactaccctaactcgtatttcactggc
cttgaatgtggacataagttttgtatgcagtgctggagtgaatatttaactaccaaaata
atggaagaaggcatgggtcagactatttcgtgtcctgctcatggttgtgatatcttagtg
gatgacaacacagttatgcgcctgatcacagattcaaaagttaaattaaagtatcagcat
ttaataacaaatagctttgtagagtgcaatcgactgttaaagtggtgtcctgccccagat
tgccaccatgttgttaaagtccaatatcctgatgctaaacctgttcgctgcaaatgtggg
cgccaattttgctttaactgtggagaaaattggcatgatcctgttaaatgtaagtggtta
aagaaatggattaaaaagtgtgatgatgacagtgaaacctccaattggattgcagccaac
acaaaggaatgtcccaaatgccatgtcacaattgagaaggatggtggttgtaatcacatg
gtctgtcgtaaccagaattgtaaagcagagttttgctgggtgtgtcttggcccatgggaa
ccacatggatctgcctggtacaactgtaaccgctataatgaggatgatgcaaaggcagca
agagatgcacaggagcgatctagggcagccctgcagaggtacctgttctactgtaatcgc
tatatgaaccacatgcagagcctgcgctttgagcacaaactatatgctcaggtgaaacag
aaaatggaggagatgcagcagcacaacatgtcctggattgaggtgcagttcctgaagaag
gcagttgatgtcctctgccagtgtcgtgccacactcatgtacacttatgtcttcgctttc
tacctcaaaaagaataaccagtccattatctttgagaataaccaagcagatctagagaat
gccacagaggtgctctcgggctaccttgaacgagatatttcccaagattctctgcaggat
ataaagcagaaagtacaagacaagtacagatactgtgagagtcgacgaagggttttgtta
cagcatgtgcatgaaggctatgaaaaagatctgtgggagtacattgaggactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (23)   
   RefSeq(nuc) (1)   
   GenBank (11)   
   EMBL (11)   
3D Structure (10)   
   PDB (10)   
Protein domain (12)   
   Pfam (12)   
All databases (91)   

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