KEGG   Homo sapiens (human): 25828
Entry
25828             CDS       T01001                                 

Gene name
TXN2, COXPD29, MT-TRX, MTRX, TRX2, TXN
Definition
(RefSeq) thioredoxin 2
  KO
K03671  thioredoxin 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05012  Parkinson disease
hsa05132  Salmonella infection
hsa05418  Fluid shear stress and atherosclerosis
Disease
H00891  Combined oxidative phosphorylation deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    25828 (TXN2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    25828 (TXN2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    25828 (TXN2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    25828 (TXN2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    25828 (TXN2)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Protein disulfide isomerase
   25828 (TXN2)
SSDB
Motif
Pfam: Thioredoxin Thioredoxin_2 Thioredoxin_7 Thioredoxin_3 DSBA Thioredoxin_8 Thioredoxin_9 HyaE DUF836 AhpC-TSA
Other DBs
NCBI-GeneID: 25828
NCBI-ProteinID: NP_036605
OMIM: 609063
HGNC: 17772
Ensembl: ENSG00000100348
Vega: OTTHUMG00000150596
Pharos: Q99757(Tbio)
UniProt: Q99757
Structure
PDB: 
1W4V 1W89 1UVZ

Position
22q12.3
AA seq 166 aa
MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTVTPNPARTIYTTRISLT
TFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDD
HTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAFLKKLIG
NT seq 501 nt   +upstreamnt  +downstreamnt
atggctcagcgacttcttctgaggaggttcctggcctctgtcatctccaggaagccctct
cagggtcagtggccacccctcacttccagagccctgcagaccccacaatgcagtcctggt
ggcctgactgtaacacccaacccagcccggacaatatacaccacgaggatctccttgaca
acctttaatatccaggatggacctgactttcaagaccgagtggtcaacagtgagacacca
gtggttgtggatttccacgcacagtggtgtggaccctgcaagatcctggggccgaggtta
gagaagatggtggccaagcagcacgggaaggtggtgatggccaaggtggatattgatgac
cacacagacctcgccattgagtatgaggtgtcagcggtgcccactgtgctggccatgaag
aatggggacgtggtggacaagtttgtgggcatcaaggatgaggatcagttggaggccttc
ctgaagaagctgattggctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (27)   
   RefSeq(nuc) (3)   
   GenBank (12)   
   EMBL (12)   
Protein domain (10)   
   Pfam (10)   
All databases (72)   

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KEGG   Homo sapiens (human): 7295
Entry
7295              CDS       T01001                                 

Gene name
TXN, TRDX, TRX, TRX1
Definition
(RefSeq) thioredoxin
  KO
K03671  thioredoxin 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05012  Parkinson disease
hsa05132  Salmonella infection
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06463  Parkinson disease
  Element
N01059  Mutation-inactivated DJ1 to KEAP1-NRF2 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    7295 (TXN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    7295 (TXN)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    7295 (TXN)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    7295 (TXN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    7295 (TXN)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Protein disulfide isomerase
   7295 (TXN)
SSDB
Motif
Pfam: Thioredoxin DIM1 Thioredoxin_8 Thioredoxin_7 Thioredoxin_2 OST3_OST6 Thioredoxin_9 Glutaredoxin AhpC-TSA Redoxin
Other DBs
NCBI-GeneID: 7295
NCBI-ProteinID: NP_003320
OMIM: 187700
HGNC: 12435
Ensembl: ENSG00000136810
Vega: OTTHUMG00000020480
Pharos: P10599(Tchem)
UniProt: P10599 H9ZYJ2
Structure
PDB: 

Position
9q31.3
AA seq 105 aa
MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD
DCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
NT seq 318 nt   +upstreamnt  +downstreamnt
atggtgaagcagatcgagagcaagactgcttttcaggaagccttggacgctgcaggtgat
aaacttgtagtagttgacttctcagccacgtggtgtgggccttgcaaaatgatcaagcct
ttctttcattccctctctgaaaagtattccaacgtgatattccttgaagtagatgtggat
gactgtcaggatgttgcttcagagtgtgaagtcaaatgcatgccaacattccagtttttt
aagaagggacaaaaggtgggtgaattttctggagccaataaggaaaagcttgaagccacc
attaatgaattagtctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (1)   
   KEGG NETWORK (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (31)   
   OC (1)   
   PHAROS (1)   
   PROTHERM (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (36)   
   RefSeq(nuc) (2)   
   GenBank (17)   
   EMBL (17)   
Protein domain (10)   
   Pfam (10)   
All databases (102)   

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