| Entry |
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| Gene name |
GAPDH, G3PD, GAPD, HEL-S-162eP
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| Definition |
(RefSeq) glyceraldehyde-3-phosphate dehydrogenase
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| KO |
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| Organism |
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| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
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| Module |
| hsa_M00001 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate |
| hsa_M00002 | Glycolysis, core module involving three-carbon compounds |
| hsa_M00003 | Gluconeogenesis, oxaloacetate => fructose-6P |
|
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| Network |
nt06017 Glycogen metabolism nt06123 TNF signaling (viruses and bacteria) |
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| Element |
| N00733 | LDHA deficiency in glycolysis |
| N00735 | ENO3 deficiency in glycolysis |
| N00737 | PGAM2 deficiency in glycolysis |
| N00928 | Escherichia NleB to TNF-NFKB signaling pathway |
|
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
2597 (GAPDH)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
2597 (GAPDH)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
2597 (GAPDH)
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
2597 (GAPDH)
05132 Salmonella infection
2597 (GAPDH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
2597 (GAPDH)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
2597 (GAPDH)
Enzymes [BR:hsa01000]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
2597 (GAPDH)
Membrane trafficking [BR:hsa04131]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
2597 (GAPDH)
Exosome [BR:hsa04147]
Exosomal proteins
Proteins found in most exosomes
2597 (GAPDH)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
12p13.31
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| AA seq |
335 aa  
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE |
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| NT seq |
1008 nt  +upstreamnt +downstreamnt
atggggaaggtgaaggtcggagtcaacggatttggtcgtattgggcgcctggtcaccagg
gctgcttttaactctggtaaagtggatattgttgccatcaatgaccccttcattgacctc
aactacatggtttacatgttccaatatgattccacccatggcaaattccatggcaccgtc
aaggctgagaacgggaagcttgtcatcaatggaaatcccatcaccatcttccaggagcga
gatccctccaaaatcaagtggggcgatgctggcgctgagtacgtcgtggagtccactggc
gtcttcaccaccatggagaaggctggggctcatttgcaggggggagccaaaagggtcatc
atctctgccccctctgctgatgcccccatgttcgtcatgggtgtgaaccatgagaagtat
gacaacagcctcaagatcatcagcaatgcctcctgcaccaccaactgcttagcacccctg
gccaaggtcatccatgacaactttggtatcgtggaaggactcatgaccacagtccatgcc
atcactgccacccagaagactgtggatggcccctccgggaaactgtggcgtgatggccgc
ggggctctccagaacatcatccctgcctctactggcgctgccaaggctgtgggcaaggtc
atccctgagctgaacgggaagctcactggcatggccttccgtgtccccactgccaacgtg
tcagtggtggacctgacctgccgtctagaaaaacctgccaaatatgatgacatcaagaag
gtggtgaagcaggcgtcggagggccccctcaagggcatcctgggctacactgagcaccag
gtggtctcctctgacttcaacagcgacacccactcctccacctttgacgctggggctggc
attgccctcaacgaccactttgtcaagctcatttcctggtatgacaacgaatttggctac
agcaacagggtggtggacctcatggcccacatggcctccaaggagtaa |
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