KEGG   Homo sapiens (human): 26030
Entry
26030             CDS       T01001                                 
Symbol
PLEKHG3, ARHGEF43, KIAA0599
Name
(RefSeq) pleckstrin homology and RhoGEF domain containing G3
  KO
K23859  pleckstrin homology domain-containing family G member 1/2/3
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    26030 (PLEKHG3)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 Pleckstrin homology (PH) domain-containing proteins
  Other PH domain-containing proteins
   26030 (PLEKHG3)
SSDB
Motif
Pfam: RhoGEF SOS1_NGEF_PH PH PH_10 PH_16 RHG20_PH
Other DBs
NCBI-GeneID: 26030
NCBI-ProteinID: NP_001295076
OMIM: 617940
HGNC: 20364
Ensembl: ENSG00000126822
UniProt: A1L390 A0A2X0SFH4
Position
14:64704424..64750249
AA seq 1219 aa
MPVSTSLHQDGSQERPVSLTSTTSSSGSSCDSRSAMEEPSSSEAPAKNGAGSLRSRHLPN
SNNNSSSWLNVKGPLSPFNSRAAAGPAHHKLSYLGRVVREIVETERMYVQDLRSIVEDYL
LKIIDTPGLLKPEQVSALFGNIENIYALNSQLLRDLDSCNSDPVAVASCFVERSQEFDIY
TQYCNNYPNSVAALTECMRDKQQAKFFRDRQELLQHSLPLGSYLLKPVQRILKYHLLLQE
IAKHFDEEEDGFEVVEDAIDTMTCVAWYINDMKRRHEHAVRLQEIQSLLINWKGPDLTTY
GELVLEGTFRVHRVRNERTFFLFDKTLLITKKRGDHFVYKGNIPCSSLMLIESTRDSLCF
TVTHYKHSKQQYSIQAKTVEEKRNWTHHIKRLILENHHATIPQKAKEAILEMDSYYPNRY
RCSPERLKKAWSSQDEVSTNVRQGRRQSEPTKHLLRQLNEKARAAGMKGKGRRESESSRS
SRRPSGRSPTSTEKRMSFESISSLPEVEPDPEAGSEQEVFSAVEGPSAEETPSDTESPEV
LETQLDAHQGLLGMDPPGDMVDFVAAESTEDLKALSSEEEEEMGGAAQEPESLLPPSVLD
QASVIAERFVSSFSRRSSVAQEDSKSSGFGSPRLVSRSSSVLSLEGSEKGLARHGSATDS
LSCQLSPEVDISVGVATEDSPSVNGMEPPSPGCPVEPDRSSCKKKESALSTRDRLLLDKI
KSYYENAEHHDAGFSVRRRESLSYIPKGLVRNSISRFNSLPRPDPEPVPPVGSKRQVGSR
PTSWALFELPGPSQAVKGDPPPISDAEFRPSSEIVKIWEGMESSGGSPGKGPGQGQANGF
DLHEPLFILEEHELGAITEESATASPESSSPTEGRSPAHLARELKELVKELSSSTQGELV
APLHPRIVQLSHVMDSHVSERVKNKVYQLARQYSLRIKSNKPVMARPPLQWEKVAPERDG
KSPTVPCLQEEAGEPLGGKGKRKPVLSLFDYEQLMAQEHSPPKPSSAGEMSPQRFFFNPS
AVSQRTTSPGGRPSARSPLSPTETFSWPDVRELCSKYASRDEARRAGGGRPRGPPVNRSH
SVPENMVEPPLSGRVGRCRSLSTKRGRGGGEAAQSPGPLPQSKPDGGETLYVTADLTLED
NRRVIVMEKGPLPSPTAGLEESSGQGPSSPVALLGQVQDFQQSAECQPKEEGSRDPADPS
QQGRVRNLREKFQALNSVG
NT seq 3660 nt   +upstreamnt  +downstreamnt
atgcctgtgtccacctccctccaccaggatggcagccaggagcggccggtgagcctgacc
tctaccacctcctcgtcgggctcctcctgtgacagtcgcagtgccatggaggagcccagc
agctccgaggctcccgccaagaatggggcaggctccctgagaagccggcatctgcccaac
agcaacaacaactccagcagctggttgaacgtgaaggggcccctctccccgttcaacagc
cgggcagcggcagggcctgcacaccacaagctcagctacctgggccgagtggtgcgggag
atcgtggagacagagcgcatgtacgtacaggacctgcgcagcatcgtggaggactacctc
ttgaagatcattgacacacccgggctgctgaagccagaacaggtcagcgccctctttggg
aacatagaaaatatctacgcgctgaacagccagctcctcagagacctggacagctgcaat
agtgaccccgtggctgtggccagctgctttgtggaaaggagccaagagtttgatatctac
actcagtattgcaacaattaccccaactccgtggccgccctgacggaatgcatgcgggac
aagcagcaggccaagttctttcgggaccggcaggagctgctacagcactcgctgcccttg
ggctcctacctgctgaagccagtccagcgcatcctcaagtaccacctgctgctccaggaa
attgccaagcattttgatgaagaagaggatggctttgaggtggtggaggatgccattgac
accatgacctgtgtggcctggtacatcaacgacatgaagaggaggcatgagcacgcggtc
cggctccaggagattcagtcactcctcatcaactggaaggggcccgacctgaccacctac
ggggagcttgtcctggagggcacattccgcgtgcatcgcgtgcgcaatgaaaggaccttt
ttcctctttgacaaaacactgcttatcaccaagaagcggggcgatcactttgtctacaag
ggcaacatcccgtgctcctccctgatgctgatcgaaagcaccagagactccctgtgcttc
actgtcacccactacaagcacagcaagcagcagtacagcatccaggccaagacagtggag
gagaaacggaactggactcaccacatcaagaggctcatcctagagaaccaccatgccacc
attccccagaaggccaaggaagccatcttggaaatggattcctattatcccaatcggtac
cgctgcagcccagagcggctgaagaaggcttggtcctcccaggatgaggtgtccaccaat
gtgcgccaggggcgccggcaatctgagccaaccaaacacctgctcaggcaactcaacgag
aaagcccgagcagcaggaatgaagggaaaggggcgcagggagtctgaaagctccaggagc
agcagaaggcccagtggccggtctccaaccagtactgagaagcgcatgagcttcgagtcc
atttcttccctgccagaggttgagccggaccctgaggctgggagtgagcaagaggtattt
tctgctgtggaagggcccagtgccgaggagacgccttcagacacagaatctccagaagtc
ctggagacacagcttgatgcccaccagggccttctggggatggaccccccaggtgacatg
gtggacttcgtggcagctgagagcactgaggaccttaaggccctgagcagcgaggaggaa
gaagaaatgggaggtgccgcccaggagcctgagagccttctgccaccctctgtgctggac
caggccagcgtcattgcggagcgatttgtcagcagcttctctcggcggagcagcgtggca
caggaggacagcaagtccagtggctttgggagcccgcggctggtcagccggagcagcagc
gtgctcagcctggagggcagcgagaagggcctggcccggcatggcagtgccacagactcc
ctcagctgtcagctctccccagaagtggacatcagtgtgggggtggccacagaggacagc
ccttctgtcaatgggatggagcccccaagcccaggctgcccagtggagcctgaccggtct
tcctgcaagaagaaggaatcagcactctccacccgagaccggctgttgctagacaagatt
aagagctattatgaaaatgcagaacaccatgatgcaggcttcagcgtccgtcgccgggag
agcctctcctacatccccaaaggactggtaagaaactccatctccaggttcaacagcctt
ccccggccagacccagagccagtacctccagtggggagcaagagacaggtgggctcccgg
ccgacttcgtgggccctgtttgagctcccaggaccaagccaggcagtcaaaggggaccca
cctcccatctcagatgctgagttccgcccatcttcagaaattgtgaagatctgggaggga
atggagtcttccggagggagccctgggaaggggccaggccagggccaggccaatggcttt
gacctgcatgagccactcttcatcctggaggagcatgagctgggagccatcacagaggag
tcggccactgcctccccggaaagctcctctcccactgaggggcgcagcccggcccacctg
gcccgggagctgaaagagctggtgaaggagctgagcagcagtacccagggggagctggtg
gccccactgcacccccgcatcgtgcagctctcccacgtaatggacagccacgtgagcgag
cgcgtcaagaacaaggtctaccagctggcccgccagtacagcctccggatcaagagcaac
aagccagtgatggccaggccaccactgcagtgggaaaaggtggcccctgagagggatggg
aagagccccactgtgccctgtctacaggaagaggctggagagccattaggtggcaaaggt
aagaggaagccggtgctgtctctatttgactatgagcagctgatggcccaggagcacagc
cctcccaagccctcctcggctggggagatgtcaccacagcgtttcttcttcaacccgtct
gctgtcagccagaggaccacctcgcctgggggccggccctccgcccggagccccctcagc
cccacagagaccttcagctggcccgacgtccgtgagctctgctccaagtatgcctcccgc
gatgaggcacgccgagcagggggcggccggccccgcggcccacccgtcaacaggagccac
tcggtgccggagaacatggtagagccacctctgtcgggcagggtgggccgctgccgcagc
ctgagcaccaagaggggccggggaggcggagaggctgcccaatcccctgggcctctgccc
cagagcaagccggatggaggcgagaccctgtatgtcactgcagacctcaccctggaggac
aaccggcgggtgattgtcatggagaagggaccccttcccagccccactgcagggctggag
gagagcagtggccagggaccaagctcaccggtggccctgctggggcaggttcaggacttc
cagcagtctgcagagtgccagccgaaggaagagggttccagggacccggcagacccgagc
cagcagggcagagtgagaaaccttagagagaagttccaggccttgaactctgtcggttga

  All links  
Disease (1)   
   OMIM (1)   
Gene (40)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (28)   
   RefSeq(nuc) (2)   
   GenBank (13)   
   EMBL (13)   
Protein domain (6)   
   Pfam (6)   
All databases (79)   

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