KEGG   Homo sapiens (human): 26190
Entry
26190             CDS       T01001                                 
Symbol
FBXW2, FBW2, Fwd2, Md6
Name
(RefSeq) F-box/WD repeat-containing protein 2 isoform 1
  KO
K10261  F-box and WD-40 domain protein 2
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    26190 (FBXW2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   SCF complex
    Target recognizing subunit (F-box)
     26190 (FBXW2)
SSDB
Motif
Pfam: Beta-prop_WDR5 Beta-prop_WDR3_1st Beta-prop_THOC3 WD40 Beta-prop_IFT122_1st WD40_Prp19 EIF3I WD40_Gbeta WD40_WDHD1_1st Beta-prop_WDR3_2nd WD40_CDC20-Fz Beta-prop_TEP1_2nd Beta-prop_CAF1B_HIR1 WDR55 Beta-prop_EML_2 Beta-prop_SCAP WD40_MABP1-WDR62_2nd Beta-prop_TEP1_C Beta-prop_WDR36-Utp21_2nd F-box-like DSE1_N F-box NBCH_WD40 Beta-prop_WDR41 Beta-prop_WDR90_POC16_2nd PAC11 Beta-prop_WDR36-Utp21_1st WDR90_beta-prop_4th Beta-prop_EML Beta-prop_WDR75_1st Beta-prop_SPT8 Beta-prop_DCAF12 Vts1 Beta-prop_NWD2_C DUF5570
Other DBs
NCBI-GeneID: 26190
NCBI-ProteinID: NP_001362817
OMIM: 609071
HGNC: 13608
UniProt: Q9UKT8
Position
9:complement(120756974..120793416)
AA seq 454 aa
MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
NT seq 1365 nt   +upstreamnt  +downstreamnt
atggagagaaaggactttgagacatggcttgataacatttctgttacatttctttctctg
acggacttgcagaaaaatgaaactctggatcacctgattagtctgagtggggcagtccag
ctcaggcatctctccaataacctagagactctcctcaagcgggacttcctcaaactcctt
cccctggagctcagtttttatttgttaaaatggctcgatcctcagactttactcacatgc
tgcctcgtctctaaacagtggaataaggtgataagtgcctgtacagaggtgtggcagact
gcatgtaaaaatttgggctggcagatagatgattctgttcaggacgctttgcactggaag
aaggtttatttgaaggctattttgagaatgaagcaactggaggaccatgaagcctttgaa
acctcgtcattaattggacacagtgccagagtgtatgcactttactacaaagatggactt
ctctgtacagggtcagatgacttgtctgcaaagctgtgggatgtgagcacagggcagtgc
gtttatggcatccagacccacacttgtgcagcggtgaagtttgatgaacagaagcttgtg
acaggctcctttgacaacactgtggcttgctgggaatggagttccggagccaggacccag
cactttcgggggcacacgggggcggtatttagcgtggactacaatgatgaactggatatc
ttggtgagcggctctgcagacttcactgtgaaagtatgggctttatctgctgggacatgc
ctgaacacactcaccgggcacacggaatgggtcaccaaggtagttttgcagaagtgcaaa
gtcaagtctctcttgcacagtcctggagactacatcctcttaagtgcagacaaatatgag
attaagatttggccaattgggagagaaatcaactgtaagtgcttaaagacattgtctgtc
tctgaggatagaagtatctgcctgcagccaagacttcattttgatggcaaatacattgtc
tgtagttcagcacttggtctctaccagtgggactttgccagttatgatattctcagggtc
atcaagactcctgagatagcaaacttggccttgcttggctttggagatatctttgccctg
ctgtttgacaaccgctacctgtacatcatggacttgcggacagagagcctgattagtcgc
tggcctctgccagagtacaggaaatcaaagagaggctcaagcttcctggcaggcgaagca
tcctggctgaatggactggatgggcacaatgacacgggcttggtctttgccaccagcatg
cctgaccacagtattcacctggtgttgtggaaggagcacggctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (57)   
   RefSeq(nuc) (23)   
   GenBank (17)   
   EMBL (17)   
Protein domain (35)   
   Pfam (35)   
All databases (124)   

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