KEGG   Homo sapiens (human): 2639
Entry
2639              CDS       T01001                                 
Symbol
GCDH, ACAD5, GCD
Name
(RefSeq) glutaryl-CoA dehydrogenase
  KO
K00252  glutaryl-CoA dehydrogenase [EC:1.3.8.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00071  Fatty acid degradation
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
Module
hsa_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Network
nt06036  Lysine degradation
  Element
N01687  Lysine degradation 3
Disease
H00178  Glutaric acidemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    2639 (GCDH)
  09105 Amino acid metabolism
   00310 Lysine degradation
    2639 (GCDH)
   00380 Tryptophan metabolism
    2639 (GCDH)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.8  With a flavin as acceptor
    1.3.8.6  glutaryl-CoA dehydrogenase (ETF)
     2639 (GCDH)
SSDB
Motif
Pfam: Acyl-CoA_dh_N Acyl-CoA_dh_1 Acyl-CoA_dh_M Acyl-CoA_dh_2 ACOX_C_alpha1
Other DBs
NCBI-GeneID: 2639
NCBI-ProteinID: NP_000150
OMIM: 608801
HGNC: 4189
Ensembl: ENSG00000105607
UniProt: Q92947
Structure
Position
19:12891129..12899999
AA seq 438 aa
MALRGVSVRLLSRGPGLHVLRTWVSSAAQTEKGGRTQSQLAKSSRPEFDWQDPLVLEEQL
TTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSS
VAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLT
EPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRGFLLEK
GMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGCLNNARYGIAWG
VLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQD
KAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIH
ALILGRAITGIQAFTASK
NT seq 1317 nt   +upstreamnt  +downstreamnt
atggccctgagaggcgtctccgtgcggctgctgagccgcggacccggcctgcacgtcctt
cgcacgtgggtctcgtcggcggcgcagaccgagaaaggcgggagaacacagagccaactg
gctaagtcctcgcgtcccgagtttgactggcaggacccgctggtgctggaggagcagctg
accacagatgagatcctcatcagggacaccttccgcacctactgccaggagagactcatg
cctcgcatcctgttggccaatcgcaacgaagtttttcatcgggagatcatttcggagatg
ggggagttgggtgtgctgggccccaccatcaaaggatatggctgtgctggggtttcgtct
gtggcctatgggctcctggcccgagagctggagcgggtggacagtggctacaggtcggcg
atgagtgtccagtcctccctcgtcatgcaccctatctatgcctatggcagcgaggaacag
cggcagaagtacctgccccagctggccaagggggagctcctgggctgcttcgggctcaca
gagcccaacagcggaagtgaccccagcagcatggagaccagagcccactacaactcatcc
aacaagagctacaccctcaatgggaccaagacctggatcacgaactcgcctatggccgat
ctgtttgtagtgtgggctcggtgtgaagatggctgcattcggggcttcctgctggagaag
gggatgcggggtctctcggcccccaggatccagggcaagttctcgctgcgggcctcagcc
acaggcatgatcatcatggacggtgtggaggtgccagaggagaatgtgctccctggtgca
tccagcctggggggtcccttcggctgcctgaacaacgcccggtacggcatcgcgtggggc
gtgcttggagcttcggagttctgcttgcacacagcccggcagtacgccctcgacaggatg
cagtttggtgtcccactggccaggaaccagctgattcagaagaagctggcagacatgctc
actgagattaccctgggccttcacgcctgcctgcagctcggccgcttgaaggaccaggac
aaggctgcccccgagatggtttctctgctgaagaggaataactgtgggaaagccctggac
atcgcccgccaggcccgagacatgctgggggggaatgggatttctgacgagtatcacgtg
atccggcacgccatgaacctggaggccgtgaacacctacgaaggtacacatgacattcac
gccctgatccttgggagagctatcacgggaatccaggcgttcacggccagcaagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (28)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (106)   
   RefSeq(nuc) (4)   
   GenBank (51)   
   EMBL (51)   
3D Structure (4)   
   PDB (4)   
Protein domain (5)   
   Pfam (5)   
All databases (149)   

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