KEGG   Homo sapiens (human): 267
Entry
267               CDS       T01001                                 

Symbol
AMFR, GP78, RNF45
Name
(RefSeq) autocrine motility factor receptor
  KO
K10636  E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    267 (AMFR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    267 (AMFR)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.36  RING-type E3 ubiquitin transferase (cysteine targeting)
     267 (AMFR)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    267 (AMFR)
  Multi subunit Ring-finger type E3
   ERAD complex
    267 (AMFR)
   LMBR1L-GP78-UBAC2 complex
    267 (AMFR)
SSDB
Motif
Pfam: G2BR zf-RING_2 zf-C3HC4_2 CUE zf-C3HC4 zf-RING_UBOX zf-C3HC4_3 zf-RING_11 zf-rbx1 zf-RING_5 zf-ANAPC11 Zn_ribbon_17 Prok-RING_4 zf-C3HC4_4
Other DBs
NCBI-GeneID: 267
NCBI-ProteinID: NP_001135
OMIM: 603243
HGNC: 463
Ensembl: ENSG00000159461
Vega: OTTHUMG00000133239
Pharos: Q9UKV5(Tbio)
UniProt: Q9UKV5
Structure
PDB: 

Position
16q13
AA seq 643 aa
MPLLFLERFPWPSLRTYTGLSGLALLGTIISAYRALSQPEAGPGEPDQLTASLQPEPPAP
ARPSAGGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKD
KFWNFIFYKFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPM
SSHGRVLSLLVAMLLSCCGLAAVCSITGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIH
LWDLNHEGTWEGKGTYVYYTDFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRY
LFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSMQAARKLPCGHLF
HNSCLRSWLEQDTSCPTCRMSLNIADNNRVREEHQGENLDENLVPVAAAEGRPRLNQHNH
FFHFDGSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDL
QLTRSVEITTDNILEGRIQVPFPTQRSDSIRPALNSPVERPSSDQEEGETSAQTERVPLD
LSPRLEETLDFGEVEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNK
SSEDDAASESFLPSEGASSDPVTLRRRMLAAAAERRLQKQQTS
NT seq 1932 nt   +upstreamnt  +downstreamnt
atgccgctgctcttcctcgagcgcttcccctggcccagcctccgcacctacacgggcctc
agcggcctggccctgctgggcaccatcatcagcgcctaccgcgcgctcagccagcccgag
gccggccccggcgagccggaccagctaacggcctcgctgcagcctgagccgccggcgccc
gcccggccgagcgccgggggaccccgggcccgcgatgtggcccagtacctgctctcagac
agcctcttcgtgtgggttctagtaaataccgcttgctgtgttttgatgttggtggctaag
ctcatccagtgtattgtgtttggccctcttcgagtgagtgagagacagcatctcaaagac
aaattttggaattttattttctacaagttcattttcatctttggtgtgctgaatgtccag
acagtggaagaggtggtcatgtggtgcctctggtttgccggacttgtctttctgcacctg
atggttcagctctgcaaggatcgatttgaatatctttccttctcgcccaccacgccgatg
agcagccacggtcgagtcctgtccctgttggttgccatgctgctttcctgctgtggactg
gcggccgtctgctccatcaccggctacacccacggaatgcacaccttggctttcatggct
gcagagtctcttcttgtgacagtgaggactgctcatgtgattttacgatacgtaattcac
ctctgggacctcaaccacgaagggacgtgggaaggaaaggggacgtatgtctattacaca
gactttgtcatggagctcactctcctgtccctggacctcatgcaccatattcacatgttg
ttatttggcaacatctggttatccatggccagcctggtcatctttatgcagctgcgttac
ctgtttcatgaggtgcaacgtcgaattcgtcggcacaagaactatctacgtgtggttgga
aacatggaggccaggtttgcagttgcaactccagaggagctggctgtcaacaatgacgac
tgtgccatctgttgggactccatgcaggctgcgcggaaactgccctgtggacatcttttc
cacaactcctgtcttcgttcctggctagaacaagacacctcctgtccaacatgcagaatg
tctcttaatattgccgacaataatcgtgtcagggaagaacatcaaggagagaacttggat
gagaatttggttcctgtagcagcagccgaagggagacctcgcttaaaccaacacaatcac
ttcttccatttcgatgggtctcggattgcgagctggctgccgagtttttcggttgaagtg
atgcacaccaccaacattcttggcattacgcaggccagcaactcccagctcaatgcaatg
gctcatcagattcaagagatgtttccccaggttccataccatctggtactgcaggacctc
cagctgacacgctcagttgaaataacaacagacaatattttagaaggacggattcaagta
ccttttcctacacagcggtcagatagcatcagacctgcattgaacagtcctgtggaaagg
ccaagcagtgaccaggaagagggagaaacttctgctcagaccgagcgtgtgccactggac
ctcagtcctcgcctggaggagacgctggacttcggcgaggtggaagtggagcccagtgag
gtggaagacttcgaggctcgtgggagccgcttctccaagtctgctgatgagagacagcgc
atgctggtgcagcgtaaggacgaactcctccagcaagctcgcaaacgtttcttgaacaaa
agttctgaagatgatgcggcctcagagagcttcctcccctcggaaggtgcgtcctctgac
cccgtgaccctgcgtcgaaggatgctggctgccgccgcggaacggaggcttcagaagcag
cagacctcctag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (49)   
   RefSeq(nuc) (5)   
   GenBank (22)   
   EMBL (22)   
Protein domain (14)   
   Pfam (14)   
All databases (95)   

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