KEGG   Homo sapiens (human): 27089
Entry
27089             CDS       T01001                                 
Symbol
UQCRQ, MC3DN4, QCR8, QP-C, QPC, UQCR7
Name
(RefSeq) ubiquinol-cytochrome c reductase complex III subunit VII
  KO
K00418  ubiquinol-cytochrome c reductase subunit 8
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04260  Cardiac muscle contraction
hsa04714  Thermogenesis
hsa04932  Non-alcoholic fatty liver disease
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05415  Diabetic cardiomyopathy
Module
hsa_M00152  Cytochrome bc1 complex
Network
nt06252  Mitochondrial ROS formation
nt06418  Oxidative phosphorylation
nt06461  Huntington disease
nt06463  Parkinson disease
  Element
N00990  Electron transfer in Complex III
N00991  Mutation-caused aberrant Htt to electron transfer in Complex III
N01046  Maneb to electron transfer in Complex III
N01395  Cadmium to electron transfer in complex III
Disease
H02086  Mitochondrial complex III deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    27089 (UQCRQ)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    27089 (UQCRQ)
  09159 Environmental adaptation
   04714 Thermogenesis
    27089 (UQCRQ)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    27089 (UQCRQ)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    27089 (UQCRQ)
   05012 Parkinson disease
    27089 (UQCRQ)
   05014 Amyotrophic lateral sclerosis
    27089 (UQCRQ)
   05016 Huntington disease
    27089 (UQCRQ)
   05020 Prion disease
    27089 (UQCRQ)
   05022 Pathways of neurodegeneration - multiple diseases
    27089 (UQCRQ)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    27089 (UQCRQ)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    27089 (UQCRQ)
SSDB
Motif
Pfam: UcrQ Cyt_b-c1_8
Other DBs
NCBI-GeneID: 27089
NCBI-ProteinID: NP_055217
OMIM: 612080
HGNC: 29594
Ensembl: ENSG00000164405
Pharos: O14949(Tbio)
UniProt: O14949
Structure
Position
5:132866642..132868847
AA seq 82 aa
MGREFGNLTRMRHVISYSLSPFEQRAYPHVFTKGIPNVLRRIRESFFRVVPQFVVFYLIY
TWGTEEFERSKRKNPAAYENDK
NT seq 249 nt   +upstreamnt  +downstreamnt
atgggccgcgagtttgggaatctgacgcggatgcggcatgtgatcagctacagcttgtca
ccgttcgagcagcgcgcctatccgcacgtcttcactaaaggaatccccaatgttctgcgc
cgcattcgggagtctttctttcgcgtggtgccgcagtttgtagtgttttatcttatctac
acatgggggactgaagagttcgagagatccaagaggaagaatccagctgcctatgaaaat
gacaaatga

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