KEGG   Homo sapiens (human): 2719Help
Entry
2719              CDS       T01001                                 

Gene name
GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Definition
(RefSeq) glypican 3
  KO
K08109  glypican 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05205  Proteoglycans in cancer
Disease
H00493  Heparan sulfate proteoglycan gene defects
H01215  Simpson-Golabi-Behmel syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05205 Proteoglycans in cancer
    2719 (GPC3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00535 Proteoglycans [BR:hsa00535]
    2719 (GPC3)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    2719 (GPC3)
Proteoglycans [BR:hsa00535]
 Cell surface proteoglycans
  Glypican family (GPI-anchored HSPG)
   2719 (GPC3)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Others
  2719 (GPC3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Glypican
Motif
Other DBs
NCBI-GeneID: 2719
NCBI-ProteinID: NP_004475
OMIM: 300037
HGNC: 4451
Ensembl: ENSG00000147257
Vega: OTTHUMG00000022448
Pharos: P51654(Tbio)
UniProt: P51654 Q53H15 I6QTG3
Position
Xq26.2
AA seq 580 aa AA seqDB search
MAGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGS
DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVR
HAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYT
QLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQVTRIFLQALNLGIEVI
NTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYI
LSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSA
YYPEDLFIDKKVLKVAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDT
LCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSMPK
GRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQ
QATPKDNEISTFHNLGNVHSPLKLLTSMAISVVCFFFLVH
NT seq 1743 nt NT seq  +upstreamnt  +downstreamnt
atggccgggaccgtgcgcaccgcgtgcttggtggtggcgatgctgctcagcttggacttc
ccgggacaggcgcagcccccgccgccgccgccggacgccacctgtcaccaagtccgctcc
ttcttccagagactgcagcccggactcaagtgggtgccagaaactcccgtgccaggatca
gatttgcaagtatgtctccctaagggcccaacatgctgctcaagaaagatggaagaaaaa
taccaactaacagcacgattgaacatggaacagctgcttcagtctgcaagtatggagctc
aagttcttaattattcagaatgctgcggttttccaagaggcctttgaaattgttgttcgc
catgccaagaactacaccaatgccatgttcaagaacaactacccaagcctgactccacaa
gcttttgagtttgtgggtgaatttttcacagatgtgtctctctacatcttgggttctgac
atcaatgtagatgacatggtcaatgaattgtttgacagcctgtttccagtcatctatacc
cagctaatgaacccaggcctgcctgattcagccttggacatcaatgagtgcctccgagga
gcaagacgtgacctgaaagtatttgggaatttccccaagcttattatgacccaggtttcc
aagtcactgcaagtcactaggatcttccttcaggctctgaatcttggaattgaagtgatc
aacacaactgatcacctgaagttcagtaaggactgtggccgaatgctcaccagaatgtgg
tactgctcttactgccagggactgatgatggttaaaccctgtggcggttactgcaatgtg
gtcatgcaaggctgtatggcaggtgtggtggagattgacaagtactggagagaatacatt
ctgtcccttgaagaacttgtgaatggcatgtacagaatctatgacatggagaacgtactg
cttggtctcttttcaacaatccatgattctatccagtatgtccagaagaatgcaggaaag
ctgaccaccactattggcaagttatgtgcccattctcaacaacgccaatatagatctgct
tattatcctgaagatctctttattgacaagaaagtattaaaagttgctcatgtagaacat
gaagaaaccttatccagccgaagaagggaactaattcagaagttgaagtctttcatcagc
ttctatagtgctttgcctggctacatctgcagccatagccctgtggcggaaaacgacacc
ctttgctggaatggacaagaactcgtggagagatacagccaaaaggcagcaaggaatgga
atgaaaaaccagttcaatctccatgagctgaaaatgaagggccctgagccagtggtcagt
caaattattgacaaactgaagcacattaaccagctcctgagaaccatgtctatgcccaaa
ggtagagttctggataaaaacctggatgaggaagggtttgaaagtggagactgcggtgat
gatgaagatgagtgcattggaggctctggtgatggaatgataaaagtgaagaatcagctc
cgcttccttgcagaactggcctatgatctggatgtggatgatgcgcctggaaacagtcag
caggcaactccgaaggacaacgagataagcacctttcacaacctcgggaacgttcattcc
ccgctgaagcttctcaccagcatggccatctcggtggtgtgcttcttcttcctggtgcac
tga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (39)   
   RefSeq(nuc) (5)   
   GenBank (17)   
   EMBL (17)   
Protein domain (1)   
   Pfam (1)   
All databases (81)   

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