KEGG   Homo sapiens (human): 28227Help
Entry
28227             CDS       T01001                                 

Gene name
PPP2R3B, NYREN8, PPP2R3L, PPP2R3LY, PR48, PR70
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B''beta
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (viruses)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    28227 (PPP2R3B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    28227 (PPP2R3B)
   04151 PI3K-Akt signaling pathway
    28227 (PPP2R3B)
   04152 AMPK signaling pathway
    28227 (PPP2R3B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    28227 (PPP2R3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    28227 (PPP2R3B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    28227 (PPP2R3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    28227 (PPP2R3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    28227 (PPP2R3B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     28227 (PPP2R3B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     28227 (PPP2R3B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_13 EF-hand_7 EF-hand_5 EF-hand_1 EF-hand_6 EF-hand_8
Motif
Other DBs
NCBI-GeneID: 28227
NCBI-ProteinID: NP_037371
OMIM: 300339
HGNC: 13417
Ensembl: ENSG00000167393
Vega: OTTHUMG00000021052
Pharos: Q9Y5P8(Tbio)
UniProt: Q9Y5P8
Structure
PDB: 

Position
Xp22.33 and Yp11.31
AA seq 575 aa AA seqDB search
MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSA
LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
NT seq 1728 nt NT seq  +upstreamnt  +downstreamnt
atgccgcccggcaaagtgctgcagccggtcctgaagatgaaggtggacgagctgttcctg
tactggctcagcgaggccagcacgcagcggatgctgcaggactgcctgcgccggatcaag
gcgcccgggcgggaccagccgaccccgggggacggggagcagcccggggcctggcccaca
gccccgctcgccgccccccggcccagcgggctcgaacccccgggaacccccgggccgggc
cctgcgctgcccctgggcgccgcctccagccccaggaacgcgccccacgttcgaggcacc
cgtagatccgcagggacgagagtagttcagacacggaaagaagagcctctgcccccggcc
acgagccaaagcattccgaccttctacttccccagaggacgcccgcaggactccgtcaac
gtggatgccgtcatcagcaagatcgagagcaccttcgcccggttcccccacgagagggcc
accatggatgacatgggcctggtggccaaggcctgcggctgccccctctactggaagggg
ccgctcttctatggcgccggcggggagcgcacgggctccgtgtccgtccacaagttcgtc
gccatgtggagaaaaatcctccagaactgccacgacgacgcggccaagttcgtccatctg
ctcatgagccccggctgcaactacctggtgcaggaggactttgtccccttcttgcaggac
gtggtgaacacgcacccggggctgtcgttcctgaaggaggcgtccgagttccactcgcgc
tacatcaccacggtcatccagcggatcttctacgccgtgaaccggtcctggtccggcagg
atcacctgcgccgagctgcggaggagctccttcctgcagaatgtggcgctgctggaggag
gaggcggacatcaaccagctgaccgaattcttctcgtacgagcatttctacgtcatctac
tgcaagttctgggagctggacacggaccacgacctgctcatcgacgcggacgacctggcg
cggcacaatgaccacgccctttctaccaagatgatagacaggatcttctcaggagcagtc
acacgaggcagaaaagtgcagaaggaagggaagatcagctatgccgactttgtctggttt
ttgatctctgaggaagacaaaaaaacaccgaccagcatcgagtactggttccgctgcatg
gacctggacggggacggcgccctgtccatgttcgagctcgagtacttctacgaggagcag
tgccgaaggctggacagcatggccatcgaggccctgcccttccaggactgcctctgccag
atgctggacctggtcaagccgaggactgaagggaagatcacgctgcaggacctgaagcgc
tgcaagctggctaacgtcttcttcgacaccttcttcaacatcgagaagtacctcgaccac
gagcagaaagagcagatctccctgctcagggacggtgacagcggcggccccgagctctcg
gactgggagaagtacgcggccgaggagtacgacatcctggtggccgaggagactgcggga
gagccctgggaggacgggttcgaggccgagctcagccctgtggagcagaagctgagtgcg
ctgcgctccccgctggcccagaggcccttcttcgaggcgccctcaccgctgggcgccgtg
gacctgtacgagtacgcatgcggggacgaggacctggagccgctgtga

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