KEGG   Homo sapiens (human): 28227Help
Entry
28227             CDS       T01001                                 

Gene name
PPP2R3B, NYREN8, PPP2R3L, PPP2R3LY, PR48, PR70
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B''beta
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    28227 (PPP2R3B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    28227 (PPP2R3B)
   04151 PI3K-Akt signaling pathway
    28227 (PPP2R3B)
   04152 AMPK signaling pathway
    28227 (PPP2R3B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    28227 (PPP2R3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    28227 (PPP2R3B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    28227 (PPP2R3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    28227 (PPP2R3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    28227 (PPP2R3B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     28227 (PPP2R3B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     28227 (PPP2R3B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_13 EF-hand_7 EF-hand_5 EF-hand_1 EF-hand_6 EF-hand_8
Motif
Other DBs
NCBI-GeneID: 28227
NCBI-ProteinID: NP_037371
OMIM: 300339
HGNC: 13417
Ensembl: ENSG00000167393
Vega: OTTHUMG00000021052
Pharos: Q9Y5P8(Tbio)
UniProt: Q9Y5P8
Structure
PDB: 

Position
Xp22.33 and Yp11.31
AA seq 575 aa AA seqDB search
MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPT
APLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPA
TSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKG
PLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQD
VVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEE
EADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAV
TRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQ
CRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDH
EQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSA
LRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL
NT seq 1728 nt NT seq  +upstreamnt  +downstreamnt
atgccgcccggcaaagtgctgcagccggtcctgaagatgaaggtggacgagctgttcctg
tactggctcagcgaggccagcacgcagcggatgctgcaggactgcctgcgccggatcaag
gcgcccgggcgggaccagccgaccccgggggacggggagcagcccggggcctggcccaca
gccccgctcgccgccccccggcccagcgggctcgaacccccgggaacccccgggccgggc
cctgcgctgcccctgggcgccgcctccagccccaggaacgcgccccacgttcgaggcacc
cgtagatccgcagggacgagagtagttcagacacggaaagaagagcctctgcccccggcc
acgagccaaagcattccgaccttctacttccccagaggacgcccgcaggactccgtcaac
gtggatgccgtcatcagcaagatcgagagcaccttcgcccggttcccccacgagagggcc
accatggatgacatgggcctggtggccaaggcctgcggctgccccctctactggaagggg
ccgctcttctatggcgccggcggggagcgcacgggctccgtgtccgtccacaagttcgtc
gccatgtggagaaaaatcctccagaactgccacgacgacgcggccaagttcgtccatctg
ctcatgagccccggctgcaactacctggtgcaggaggactttgtccccttcttgcaggac
gtggtgaacacgcacccggggctgtcgttcctgaaggaggcgtccgagttccactcgcgc
tacatcaccacggtcatccagcggatcttctacgccgtgaaccggtcctggtccggcagg
atcacctgcgccgagctgcggaggagctccttcctgcagaatgtggcgctgctggaggag
gaggcggacatcaaccagctgaccgaattcttctcgtacgagcatttctacgtcatctac
tgcaagttctgggagctggacacggaccacgacctgctcatcgacgcggacgacctggcg
cggcacaatgaccacgccctttctaccaagatgatagacaggatcttctcaggagcagtc
acacgaggcagaaaagtgcagaaggaagggaagatcagctatgccgactttgtctggttt
ttgatctctgaggaagacaaaaaaacaccgaccagcatcgagtactggttccgctgcatg
gacctggacggggacggcgccctgtccatgttcgagctcgagtacttctacgaggagcag
tgccgaaggctggacagcatggccatcgaggccctgcccttccaggactgcctctgccag
atgctggacctggtcaagccgaggactgaagggaagatcacgctgcaggacctgaagcgc
tgcaagctggctaacgtcttcttcgacaccttcttcaacatcgagaagtacctcgaccac
gagcagaaagagcagatctccctgctcagggacggtgacagcggcggccccgagctctcg
gactgggagaagtacgcggccgaggagtacgacatcctggtggccgaggagactgcggga
gagccctgggaggacgggttcgaggccgagctcagccctgtggagcagaagctgagtgcg
ctgcgctccccgctggcccagaggcccttcttcgaggcgccctcaccgctgggcgccgtg
gacctgtacgagtacgcatgcggggacgaggacctggagccgctgtga

KEGG   Homo sapiens (human): 55012Help
Entry
55012             CDS       T01001                                 

Gene name
PPP2R3C, C14orf10, G4-1, G5pr, GDRM, SPGF36
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B''gamma
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    55012 (PPP2R3C)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    55012 (PPP2R3C)
   04151 PI3K-Akt signaling pathway
    55012 (PPP2R3C)
   04152 AMPK signaling pathway
    55012 (PPP2R3C)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    55012 (PPP2R3C)
  09156 Nervous system
   04728 Dopaminergic synapse
    55012 (PPP2R3C)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    55012 (PPP2R3C)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    55012 (PPP2R3C)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    55012 (PPP2R3C)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     55012 (PPP2R3C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     55012 (PPP2R3C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_7 EF-hand_6 EF-hand_13 EF-hand_1 EF-hand_5 DUF61
Motif
Other DBs
NCBI-GeneID: 55012
NCBI-ProteinID: NP_060387
OMIM: 615902
HGNC: 17485
Ensembl: ENSG00000092020
Vega: OTTHUMG00000140224
Pharos: Q969Q6(Tbio)
UniProt: Q969Q6
Position
14q13.2
AA seq 453 aa AA seqDB search
MDWKEVLRRRLATPNTCPNKKKSEQELKDEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFY
YRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQTPPMIGEEAMINY
ENFLKVGEKAGAKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLY
DVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKI
QDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSR
YGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGY
LNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTV
TTILIDLNGFWTYENREALVANDSENSADLDDT
NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt
atggactggaaagaagttcttcgtcggcgcctagcgacgcccaacacctgtccaaacaaa
aaaaaaagtgaacaagaattaaaagatgaagaaatggatttatttacaaaatattactcc
gaatggaaaggaggtagaaaaaacacaaatgaattctataagaccattccccggttttat
tataggctgcctgctgaagatgaagtcttactacagaaattaagagaggaatcaagagct
gtctttctacaaagaaaaagcagagaactgttagataatgaagaattacagaacttatgg
tttttgctggacaaacaccagacaccacctatgattggagaggaagcgatgatcaattac
gaaaactttttgaaggttggtgaaaaggctggagcaaagtgcaagcaatttttcacagca
aaagtctttgctaaactccttcatacagattcatatggaagaatttccatcatgcagttc
tttaattatgtcatgagaaaagtttggcttcatcaaacaagaataggactcagtttatat
gatgtcgctgggcaggggtaccttcgggaatctgatttagaaaactacatattggaactt
atccctacgttgccacaattagatggtctggaaaaatctttctactccttttatgtttgt
acagcagttaggaagttcttcttctttttagatcctttaagaacaggaaagataaaaatt
caagatattttagcatgcagcttcctagatgatttattggagctaagggatgaggaactg
tccaaggagagtcaagaaacaaattggttttctgctccttctgccctaagagtttatggc
cagtacttgaatcttgataaagatcacaatggcatgctcagtaaagaagaactctcacgc
tatggaacagctaccatgaccaatgtcttcttagaccgtgttttccaggagtgtctcact
tatgatggagaaatggactataagacctacttggactttgtccttgcattagaaaacaga
aaggaacctgcagctctacaatatattttcaaactgcttgatattgagaacaaaggatac
ctgaatgtcttttcacttaattatttctttagggccatacaggaactaatgaaaatccat
ggacaagatcctgtttcatttcaagatgtcaaggatgaaatctttgacatggtaaaacca
aaggatcctttgaaaatctctcttcaggatttaatcaacagtaatcaaggagacacagta
accaccattctaatcgatttgaatggcttctggacttacgagaacagagaggctcttgtt
gcaaatgacagtgaaaactctgcagaccttgatgatacatga

KEGG   Homo sapiens (human): 5515Help
Entry
5515              CDS       T01001                                 

Gene name
PPP2CA, NEDLBA, PP2Ac, PP2CA, PP2Calpha, RP-C
Definition
(RefSeq) protein phosphatase 2 catalytic subunit alpha
  KO
K04382  serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa04730  Long-term depression
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Drug target
Fostriecin sodium: D04262
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5515 (PPP2CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    5515 (PPP2CA)
   04390 Hippo signaling pathway
    5515 (PPP2CA)
   04071 Sphingolipid signaling pathway
    5515 (PPP2CA)
   04151 PI3K-Akt signaling pathway
    5515 (PPP2CA)
   04152 AMPK signaling pathway
    5515 (PPP2CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    5515 (PPP2CA)
   04136 Autophagy - other
    5515 (PPP2CA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    5515 (PPP2CA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5515 (PPP2CA)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5515 (PPP2CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    5515 (PPP2CA)
   04730 Long-term depression
    5515 (PPP2CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5515 (PPP2CA)
   05165 Human papillomavirus infection
    5515 (PPP2CA)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5515 (PPP2CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5515 (PPP2CA)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5515 (PPP2CA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5515 (PPP2CA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5515 (PPP2CA)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Catalytic subunits
     5515 (PPP2CA)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5515 (PPP2CA)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5515 (PPP2CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Metallophos STPPase_N Glyco_hydro_65N DUF5378 YqzH
Motif
Other DBs
NCBI-GeneID: 5515
NCBI-ProteinID: NP_002706
OMIM: 176915
HGNC: 9299
Ensembl: ENSG00000113575
Vega: OTTHUMG00000129119
Pharos: P67775(Tchem)
UniProt: P67775 B3KUN1
Structure
PDB: 

Position
5q31.1
AA seq 309 aa AA seqDB search
MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG
QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES
RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI
RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA
HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV
TRRTPDYFL
NT seq 930 nt NT seq  +upstreamnt  +downstreamnt
atggacgagaaggtgttcaccaaggagctggaccagtggatcgagcagctgaacgagtgc
aagcagctgtccgagtcccaggtcaagagcctctgcgagaaggctaaagaaatcctgaca
aaagaatccaacgtgcaagaggttcgatgtccagttactgtctgtggagatgtgcatggg
caatttcatgatctcatggaactgtttagaattggtggcaaatcaccagatacaaattac
ttgtttatgggagattatgttgacagaggatattattcagttgaaacagttacactgctt
gtagctcttaaggttcgttaccgtgaacgcatcaccattcttcgagggaatcatgagagc
agacagatcacacaagtttatggtttctatgatgaatgtttaagaaaatatggaaatgca
aatgtttggaaatattttacagatctttttgactatcttcctctcactgccttggtggat
gggcagatcttctgtctacatggtggtctctcgccatctatagatacactggatcatatc
agagcacttgatcgcctacaagaagttccccatgagggtccaatgtgtgacttgctgtgg
tcagatccagatgaccgtggtggttggggtatatctcctcgaggagctggttacaccttt
gggcaagatatttctgagacatttaatcatgccaatggcctcacgttggtgtctagagct
caccagctagtgatggagggatataactggtgccatgaccggaatgtagtaacgattttc
agtgctccaaactattgttatcgttgtggtaaccaagctgcaatcatggaacttgacgat
actctaaaatactctttcttgcagtttgacccagcacctcgtagaggcgagccacatgtt
actcgtcgtaccccagactacttcctgtaa

KEGG   Homo sapiens (human): 5516Help
Entry
5516              CDS       T01001                                 

Gene name
PPP2CB, PP2Abeta, PP2CB
Definition
(RefSeq) protein phosphatase 2 catalytic subunit beta
  KO
K04382  serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04136  Autophagy - other
hsa04140  Autophagy - animal
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa04730  Long-term depression
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Drug target
Fostriecin sodium: D04262
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5516 (PPP2CB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    5516 (PPP2CB)
   04390 Hippo signaling pathway
    5516 (PPP2CB)
   04071 Sphingolipid signaling pathway
    5516 (PPP2CB)
   04151 PI3K-Akt signaling pathway
    5516 (PPP2CB)
   04152 AMPK signaling pathway
    5516 (PPP2CB)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    5516 (PPP2CB)
   04136 Autophagy - other
    5516 (PPP2CB)
  09143 Cell growth and death
   04114 Oocyte meiosis
    5516 (PPP2CB)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5516 (PPP2CB)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5516 (PPP2CB)
  09156 Nervous system
   04728 Dopaminergic synapse
    5516 (PPP2CB)
   04730 Long-term depression
    5516 (PPP2CB)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5516 (PPP2CB)
   05165 Human papillomavirus infection
    5516 (PPP2CB)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5516 (PPP2CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5516 (PPP2CB)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5516 (PPP2CB)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5516 (PPP2CB)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5516 (PPP2CB)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Catalytic subunits
     5516 (PPP2CB)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5516 (PPP2CB)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5516 (PPP2CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Metallophos STPPase_N Glyco_hydro_65N DUF5378
Motif
Other DBs
NCBI-GeneID: 5516
NCBI-ProteinID: NP_001009552
OMIM: 176916
HGNC: 9300
Ensembl: ENSG00000104695
Vega: OTTHUMG00000163949
Pharos: P62714(Tbio)
UniProt: P62714 A0A140VJS0
Position
8p12
AA seq 309 aa AA seqDB search
MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHG
QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHES
RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI
RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA
HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV
TRRTPDYFL
NT seq 930 nt NT seq  +upstreamnt  +downstreamnt
atggacgacaaggcgttcaccaaggagctggaccagtgggtcgagcagctgaacgagtgt
aagcagctgaacgagaaccaagtgcggacgctgtgcgagaaggcaaaggaaattttaaca
aaagaatcaaatgtgcaagaggttcgttgccctgttactgtctgtggagatgtgcatggt
caatttcatgatcttatggaactctttagaattggtggaaaatcaccggatacaaactac
ttattcatgggtgactatgtagacagaggatattattcagtggagactgtgactcttctt
gtagcattaaaggtgcgttatccagaacgcattacaatattgagaggaaatcacgaaagc
cgacaaattacccaagtatatggcttttatgatgaatgtctgcgaaagtatgggaatgcc
aacgtttggaaatattttacagatctctttgattatcttccacttacagctttagtagat
ggacagatattctgcctccatggtggcctctctccatccatagacacactggatcatata
agagccctggatcgtttacaggaagttccacatgagggcccaatgtgtgatctgttatgg
tcagatccagatgatcgtggtggatggggtatttcaccacgtggtgctggctacacattt
ggacaagacatttctgaaacctttaaccatgccaatggtctcacactggtttctcgtgcc
caccagcttgtaatggagggatacaattggtgtcatgatcggaatgtggttaccattttc
agtgcacccaattactgttatcgttgtgggaaccaggctgctatcatggaattagatgac
actttaaaatattccttccttcaatttgacccagcgcctcgtcgtggtgagcctcatgtt
acacggcgcaccccagactacttcctataa

KEGG   Homo sapiens (human): 5518Help
Entry
5518              CDS       T01001                                 

Gene name
PPP2R1A, MRD36, PP2A-Aalpha, PP2AA, PP2AAALPHA, PR65A
Definition
(RefSeq) protein phosphatase 2 scaffold subunit Aalpha
  KO
K03456  serine/threonine-protein phosphatase 2A regulatory subunit A
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa04730  Long-term depression
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5518 (PPP2R1A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    5518 (PPP2R1A)
   04390 Hippo signaling pathway
    5518 (PPP2R1A)
   04071 Sphingolipid signaling pathway
    5518 (PPP2R1A)
   04151 PI3K-Akt signaling pathway
    5518 (PPP2R1A)
   04152 AMPK signaling pathway
    5518 (PPP2R1A)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5518 (PPP2R1A)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5518 (PPP2R1A)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5518 (PPP2R1A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5518 (PPP2R1A)
   04730 Long-term depression
    5518 (PPP2R1A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5518 (PPP2R1A)
   05165 Human papillomavirus infection
    5518 (PPP2R1A)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5518 (PPP2R1A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5518 (PPP2R1A)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5518 (PPP2R1A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5518 (PPP2R1A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5518 (PPP2R1A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HEAT HEAT_2 Vac14_Fab1_bd HEAT_EZ Cnd1 Adaptin_N CLASP_N TAF6_C M11L Spore_Cse60
Motif
Other DBs
NCBI-GeneID: 5518
NCBI-ProteinID: NP_055040
OMIM: 605983
HGNC: 9302
Ensembl: ENSG00000105568
Vega: OTTHUMG00000137367
Pharos: P30153(Tbio)
UniProt: P30153 A8K7B7
Structure
PDB: 

Position
19q13.41
AA seq 589 aa AA seqDB search
MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY
DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHS
PSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPM
VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL
EALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA
AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN
TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR
LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHA
TIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNV
AKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA
NT seq 1770 nt NT seq  +upstreamnt  +downstreamnt
atggcggcggccgacggcgacgactcgctgtaccccatcgcggtgctcatagacgaactc
cgcaatgaggacgttcagcttcgcctcaacagcatcaagaagctgtccaccatcgccttg
gcccttggggttgaaaggacccgaagtgagcttctgcctttccttacagataccatctat
gatgaagatgaggtcctcctggccctggcagaacagctgggaaccttcactaccctggtg
ggaggcccagagtacgtgcactgcctgctgccaccgctggagtcgctggccacagtggag
gagacagtggtgcgggacaaggcagtggagtccttacgggccatctcacacgagcactcg
ccctctgacctggaggcgcactttgtgccgctagtgaagcggctggcgggcggcgactgg
ttcacctcccgcacctcggcctgcggcctcttctccgtctgctacccccgagtgtccagt
gctgtgaaggcggaacttcgacagtacttccggaacctgtgctcagatgacacccccatg
gtgcggcgggccgcagcctccaagctgggggagtttgccaaggtgctggagctggacaac
gtcaagagtgagatcatccccatgttctccaacctggcctctgacgagcaggactcggtg
cggctgctggcggtggaggcgtgcgtgaacatcgcccagcttctgccccaggaggatctg
gaggccctggtgatgcccactctgcgccaggccgctgaagacaagtcctggcgcgtccgc
tacatggtggctgacaagttcacagagctccagaaagcagtggggcctgagatcaccaag
acagacctggtccctgccttccagaacctgatgaaagactgtgaggccgaggtgagggcc
gcagcctcccacaaggtcaaagagttctgtgaaaacctctcagctgactgtcgggagaat
gtgatcatgtcccagatcttgccctgcatcaaggagctggtgtccgatgccaaccaacat
gtcaagtctgccctggcctcagtcatcatgggtctctctcccatcttgggcaaagacaac
accatcgagcacctcttgcccctcttcctggctcagctgaaggatgagtgccctgaggta
cggctgaacatcatctctaacctggactgtgtgaacgaggtgattggcatccggcagctg
tcccagtccctgctccctgccattgtggagctggctgaggacgccaagtggcgggtgcgg
ctggccatcattgagtacatgcccctcctggctggacagctgggagtggagttctttgat
gagaaacttaactccttgtgcatggcctggcttgtggatcatgtatatgccatccgcgag
gcagccaccagcaacctgaagaagctagtggaaaagtttgggaaggagtgggcccatgcc
acaatcatccccaaggtcttggccatgtccggagaccccaactacctgcaccgcatgact
acgctcttctgcatcaatgtgctgtctgaggtctgtgggcaggacatcaccaccaagcac
atgctacccacggttctgcgcatggctggggacccggttgccaatgtccgcttcaatgtg
gccaagtctctgcagaagatagggcccatcctggacaacagcaccttgcagagtgaagtc
aagcccatcctagagaagctgacccaggaccaggatgtggacgtcaaatactttgcccag
gaggctctgactgttctgtctctcgcctga

KEGG   Homo sapiens (human): 5519Help
Entry
5519              CDS       T01001                                 

Gene name
PPP2R1B, PP2A-Abeta, PR65B
Definition
(RefSeq) protein phosphatase 2 scaffold subunit Abeta
  KO
K03456  serine/threonine-protein phosphatase 2A regulatory subunit A
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa04730  Long-term depression
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5519 (PPP2R1B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    5519 (PPP2R1B)
   04390 Hippo signaling pathway
    5519 (PPP2R1B)
   04071 Sphingolipid signaling pathway
    5519 (PPP2R1B)
   04151 PI3K-Akt signaling pathway
    5519 (PPP2R1B)
   04152 AMPK signaling pathway
    5519 (PPP2R1B)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5519 (PPP2R1B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5519 (PPP2R1B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5519 (PPP2R1B)
  09156 Nervous system
   04728 Dopaminergic synapse
    5519 (PPP2R1B)
   04730 Long-term depression
    5519 (PPP2R1B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5519 (PPP2R1B)
   05165 Human papillomavirus infection
    5519 (PPP2R1B)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5519 (PPP2R1B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5519 (PPP2R1B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5519 (PPP2R1B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5519 (PPP2R1B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5519 (PPP2R1B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HEAT HEAT_2 Vac14_Fab1_bd HEAT_EZ Cnd1 Adaptin_N M11L CLASP_N Cas_Csm6
Motif
Other DBs
NCBI-GeneID: 5519
NCBI-ProteinID: NP_002707
OMIM: 603113
HGNC: 9303
Ensembl: ENSG00000137713
Vega: OTTHUMG00000166741
Pharos: P30154(Tbio)
UniProt: P30154
Position
11q23.1
AA seq 601 aa AA seqDB search
MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTR
SELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKA
VESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQ
QFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEAC
VSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQ
NLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASV
IMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAI
VELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK
LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKM
AGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLAL
A
NT seq 1806 nt NT seq  +upstreamnt  +downstreamnt
atggcgggcgcatcagagctcgggaccggcccaggagcagcgggtggagatggagatgat
tcgctatacccgatcgcggttttaatcgacgagctccgcaatgaagacgtgcagctccga
ctcaacagtattaagaagttatcaacaattgccctagcacttggagtagaaaggacccga
agtgaattgttgccatttcttacagatacaatttatgatgaagatgaggtactattagct
cttgctgagcagctgggaaatttcactggcctagtgggaggtcctgactttgcccactgt
ctgctgcctcctttggaaaatctggcaactgtggaagagactgttgttcgtgacaaggct
gtggagtccctgagacagatctcccaggagcatactcctgttgctctggaagcttatttt
gtacctctggtgaaacgcttagcaagtggggattggttcacctctcgcacatctgcatgt
ggtttgttcagcgtttgctatcccagggcatcaaatgctgttaaagcagaaatcagacag
caattccgttccttgtgctcagatgacacaccaatggtacgacgtgctgctgcttccaaa
ttgggtgaatttgcaaaagttttggaattagacagtgtgaaaagtgaaattgttccactg
ttcactagtctagcttcagatgaacaggattcagtgcgcctccttgctgtggaagcttgt
gtcagtattgcccagttattgtctcaggatgaccttgagactttggtgatgcctacactt
cgacaagcagcagaagataaatcttggcgcgttcgctatatggtggctgacagattttca
gagctccagaaagccatgggtcctaaaatcaccctaaatgacctcatccccgcctttcag
aacctacttaaagactgtgaagctgaagtccgggcagctgctgcccacaaagtaaaagaa
cttggtgagaacttgcccattgaagatagagagaccataattatgaatcaaattctgcct
tatataaaggaattagtatccgataccaatcaacatgtcaaatcggctctagcttctgta
attatgggattgtctactattttgggcaaagaaaataccattgaacatcttctacctctt
ttcttagctcagttaaaggatgagtgtcctgacgttcgtttgaatatcatctccaatttg
gattgtgtaaatgaagtgattggaatccgtcagctctctcagtctctccttcctgccata
gtggagctggcagaagatgccaaatggagggtccgcctggccatcattgagtatatgccg
ctgctggcaggccagctgggtgtggaattctttgatgaaaagctgaattctttatgtatg
gcttggctcgtggaccatgtatacgccatccgagaagctgccaccaacaacctcatgaaa
ctagttcagaagtttggtacagagtgggcccaaaatactattgttcccaaagtgttagta
atggcaaatgatcctaattacttgcatagaatgaccactttattctgcattaatgcactg
tctgaggcctgtggtcaggaaataactactaagcaaatgctgcccatcgtattaaaaatg
gcaggagaccaagtagcaaatgttcgcttcaatgtggccaaatctctacaaaagattgga
ccaattctagataccaatgctttacagggagaagtgaagccagtactacagaagttaggt
caagatgaagacatggatgtcaaatactttgcacaggaagctataagtgttcttgcattg
gcataa

KEGG   Homo sapiens (human): 5520Help
Entry
5520              CDS       T01001                                 

Gene name
PPP2R2A, B55A, B55ALPHA, PR52A, PR55A, PR55alpha
Definition
(RefSeq) protein phosphatase 2 regulatory subunit Balpha
  KO
K04354  serine/threonine-protein phosphatase 2A regulatory subunit B
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5520 (PPP2R2A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5520 (PPP2R2A)
   04071 Sphingolipid signaling pathway
    5520 (PPP2R2A)
   04151 PI3K-Akt signaling pathway
    5520 (PPP2R2A)
   04152 AMPK signaling pathway
    5520 (PPP2R2A)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5520 (PPP2R2A)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5520 (PPP2R2A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5520 (PPP2R2A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5520 (PPP2R2A)
   05165 Human papillomavirus infection
    5520 (PPP2R2A)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5520 (PPP2R2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5520 (PPP2R2A)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5520 (PPP2R2A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5520 (PPP2R2A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5520 (PPP2R2A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ANAPC4_WD40
Motif
Other DBs
NCBI-GeneID: 5520
NCBI-ProteinID: NP_002708
OMIM: 604941
HGNC: 9304
Ensembl: ENSG00000221914
Vega: OTTHUMG00000163850
Pharos: P63151(Tchem)
UniProt: P63151 A0A140VJT0
Structure
PDB: 

Position
8p21.2
AA seq 447 aa AA seqDB search
MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQE
NKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIK
LWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHI
NSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCN
TFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYM
MTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTG
SYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKIL
HTAWHPKENIIAVATTNNLYIFQDKVN
NT seq 1344 nt NT seq  +upstreamnt  +downstreamnt
atggcaggagctggaggagggaatgatattcagtggtgtttttctcaggtgaaaggagca
gtagatgatgatgtagcagaagcagatataatttctacagtagaatttaatcattctgga
gaattactagcaacaggagataaaggtggtagagttgtcatctttcaacaggagcaggag
aacaaaatccagtctcatagcagaggagaatataatgtttacagcaccttccagagccat
gaaccagagtttgactacttgaaaagtttagaaatagaagaaaagatcaacaaaattagg
tggttaccccagaaaaatgctgctcagtttttattgtctaccaatgataaaacaataaaa
ttatggaaaatcagtgaaagggacaaaagaccagaagggtataacttgaaagaggaggat
ggaaggtatagagatcctactacagttactacactacgagtgccagtctttaggcctatg
gatctaatggttgaggccagtccacgaagaatatttgccaatgctcatacatatcacatc
aactcaatttctattaatagtgattatgaaacatatttatctgcagatgatttgcggatt
aatctttggcatctggaaattacagacaggagttttaacattgtggatatcaagcctgcc
aatatggaagagctaacagaggtgattacagcagcagaatttcatccaaacagctgtaac
acatttgtatacagcagcagtaaaggaactattcggctatgtgacatgagggcatctgcc
ctctgtgatagacattctaaattgtttgaagaacctgaagatcccagtaacaggtcattt
ttttccgaaatcatctcctctatttcggatgtaaaattcagccatagtggtcgatatatg
atgactagagactatttgtcagtcaaaatttgggacttaaatatggaaaacaggcctgtg
gaaacataccaggtgcatgaatacctcagaagtaaactctgttcactgtatgaaaatgac
tgcatatttgacaaatttgaatgttgttggaatggatctgacagtgttgtcatgactgga
tcttacaataatttcttcagaatgtttgacagaaacacaaagcgagacataaccctagaa
gcatcgcgggaaaacaataagcctcgcacagttctgaagcctcgcaaagtctgtgcaagt
ggcaagcgaaagaaagatgaaataagtgttgacagcctagacttcaataagaaaatcctt
cacacagcctggcaccccaaggaaaatatcattgccgtagctactacaaacaatctgtat
atatttcaagacaaagtgaattag

KEGG   Homo sapiens (human): 5521Help
Entry
5521              CDS       T01001                                 

Gene name
PPP2R2B, B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12
Definition
(RefSeq) protein phosphatase 2 regulatory subunit Bbeta
  KO
K04354  serine/threonine-protein phosphatase 2A regulatory subunit B
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5521 (PPP2R2B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5521 (PPP2R2B)
   04071 Sphingolipid signaling pathway
    5521 (PPP2R2B)
   04151 PI3K-Akt signaling pathway
    5521 (PPP2R2B)
   04152 AMPK signaling pathway
    5521 (PPP2R2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5521 (PPP2R2B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5521 (PPP2R2B)
  09156 Nervous system
   04728 Dopaminergic synapse
    5521 (PPP2R2B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5521 (PPP2R2B)
   05165 Human papillomavirus infection
    5521 (PPP2R2B)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5521 (PPP2R2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5521 (PPP2R2B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5521 (PPP2R2B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5521 (PPP2R2B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5521 (PPP2R2B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Other DBs
NCBI-GeneID: 5521
NCBI-ProteinID: NP_858062
OMIM: 604325
HGNC: 9305
Ensembl: ENSG00000156475
Vega: OTTHUMG00000163381
Pharos: Q00005(Tbio)
UniProt: Q00005
Position
5q32
AA seq 446 aa AA seqDB search
MKCFSRYLPYIFRPPNTILSSSCHTEADIISTVEFNHTGELLATGDKGGRVVIFQREQES
KNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKL
WKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHIN
SISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNT
FVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIM
TRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGS
YNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKILH
TAWHPSENIIAVAATNNLYIFQDKVN
NT seq 1341 nt NT seq  +upstreamnt  +downstreamnt
atgaaatgcttctctcgttacctgccttacatcttcagacctccgaacaccatcctttct
tccagctgccacacagaagctgacattatctctacggtagaattcaaccacacgggagaa
ttactagcgacaggggacaaggggggtcgggttgtaatatttcaacgagagcaggagagt
aaaaatcaggttcatcgtaggggtgaatacaatgtttacagcacattccagagccatgaa
cccgagttcgattacctgaagagtttagaaatagaagaaaaaatcaataaaataagatgg
ctcccccagcagaatgcagcttactttcttctgtctactaatgataaaactgtgaagctg
tggaaagtcagcgagcgtgataagaggccagaaggctacaatctgaaagatgaggagggc
cggctccgggatcctgccaccatcacaaccctgcgggtgcctgtcctgagacccatggac
ctgatggtggaggccaccccacgaagagtatttgccaacgcacacacatatcacatcaac
tccatatctgtcaacagcgactatgaaacctacatgtccgctgatgacctgaggattaac
ctatggaactttgaaataaccaatcaaagttttaatattgtggacattaagccagccaac
atggaggagctcacggaggtgatcacagcagccgagttccacccccatcattgcaacacc
ttcgtgtacagcagcagcaaagggacaatccggctgtgtgacatgcgggcatctgccctg
tgtgacaggcacaccaaattttttgaagagccggaagatccaagcaacagatcatttttc
tctgaaattatctcttcgatttcggatgtgaagttcagccacagtgggaggtatatcatg
accagggactacttgaccgtcaaagtctgggatctcaacatggaaaaccgccccatcgag
acttaccaggttcatgactacctccgcagcaagctgtgttccctctatgaaaatgactgc
atttttgataaatttgagtgtgtgtggaatgggtcagacagtgtcatcatgacaggctcc
tacaacaacttcttcaggatgttcgacagaaacaccaagcgtgatgtgacccttgaggct
tcgagggaaaacagcaagccccgggctatcctcaaaccccgaaaagtgtgtgtggggggc
aagcggagaaaagacgagatcagtgtcgacagtctggactttagcaaaaagatcttgcat
acagcttggcatccttcagaaaatattatagcagtggcggctacaaataacctatatata
ttccaggacaaggttaactag

KEGG   Homo sapiens (human): 5522Help
Entry
5522              CDS       T01001                                 

Gene name
PPP2R2C, B55-GAMMA, B55gamma, IMYPNO, IMYPNO1, PR52, PR55G
Definition
(RefSeq) protein phosphatase 2 regulatory subunit Bgamma
  KO
K04354  serine/threonine-protein phosphatase 2A regulatory subunit B
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5522 (PPP2R2C)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    5522 (PPP2R2C)
   04071 Sphingolipid signaling pathway
    5522 (PPP2R2C)
   04151 PI3K-Akt signaling pathway
    5522 (PPP2R2C)
   04152 AMPK signaling pathway
    5522 (PPP2R2C)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    5522 (PPP2R2C)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5522 (PPP2R2C)
  09156 Nervous system
   04728 Dopaminergic synapse
    5522 (PPP2R2C)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    5522 (PPP2R2C)
   05165 Human papillomavirus infection
    5522 (PPP2R2C)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    5522 (PPP2R2C)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5522 (PPP2R2C)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5522 (PPP2R2C)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5522 (PPP2R2C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5522 (PPP2R2C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Other DBs
NCBI-GeneID: 5522
NCBI-ProteinID: NP_065149
OMIM: 605997
HGNC: 9306
Ensembl: ENSG00000074211
Vega: OTTHUMG00000090445
Pharos: Q9Y2T4(Tbio)
UniProt: Q9Y2T4
Position
4p16.1
AA seq 447 aa AA seqDB search
MGEDTDTRKINHSFLRDHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNA
PHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKI
TERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSIS
VNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVY
SSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRD
YLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNN
FFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAW
HPAENIIAIAATNNLYIFQDKVNSDMH
NT seq 1344 nt NT seq  +upstreamnt  +downstreamnt
atgggcgaggacacggacacgcggaaaattaaccacagcttcctgcgggaccacagctat
gtgactgaagctgacatcatctctaccgttgagttcaaccacacgggagagctgctggcc
acaggtgacaagggcggccgggtcgtcatcttccagcgggaaccagagagtaaaaatgcg
ccccacagccagggcgaatacgacgtgtacagcactttccagagccacgagccggagttt
gactatctcaagagcctggagatagaggagaagatcaacaagatcaagtggctcccacag
cagaacgccgcccactcactcctgtccaccaacgataaaactatcaaattatggaagatt
accgaacgagataaaaggcccgaaggatacaacctgaaggatgaagaggggaaacttaag
gacctgtccacggtgacgtcactgcaggtgccagtgctgaagcccatggatctgatggtg
gaggtgagccctcggaggatctttgccaatggccacacctaccacatcaactccatctcc
gtcaacagtgactgcgagacctacatgtcggcggatgacctgcgcatcaacctctggcac
ctggccatcaccgacaggagcttcaacatcgtggacatcaagccggccaacatggaggac
cttacggaggtgatcacagcatctgagttccatccgcaccactgcaacctcttcgtctac
agcagcagcaagggctccctgcggctctgcgacatgcgggcagctgccctgtgtgacaag
cattccaagctctttgaagagcctgaggaccccagtaaccgctcattcttctcggaaatc
atctcctccgtgtccgacgtgaagttcagccacagcggccgctacatgctcacccgggac
taccttacagtcaaggtctgggacctgaacatggaggcaagacccatagagacctaccag
gtccatgactaccttcggagcaagctctgttccctgtacgagaacgactgcattttcgac
aagtttgaatgtgcctggaacgggagcgacagcgtcatcatgaccggggcctacaacaac
ttcttccgcatgttcgatcggaacaccaagcgggacgtgaccctggaggcctcgagggaa
agcagcaagccccgggctgtgctcaagccacggcgcgtgtgcgtggggggcaagcgccgg
cgtgatgacatcagtgtggacagcttggacttcaccaagaagatcctgcacacggcctgg
cacccggctgagaacatcattgccatcgccgccaccaacaacctgtacatcttccaggac
aaggtaaactctgacatgcactag

KEGG   Homo sapiens (human): 5523Help
Entry
5523              CDS       T01001                                 

Gene name
PPP2R3A, PPP2R3, PR130, PR72
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B''alpha
  KO
K11583  serine/threonine-protein phosphatase 2A regulatory subunit B''
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5523 (PPP2R3A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5523 (PPP2R3A)
   04151 PI3K-Akt signaling pathway
    5523 (PPP2R3A)
   04152 AMPK signaling pathway
    5523 (PPP2R3A)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5523 (PPP2R3A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5523 (PPP2R3A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5523 (PPP2R3A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5523 (PPP2R3A)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5523 (PPP2R3A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5523 (PPP2R3A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5523 (PPP2R3A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: EF-hand_13 EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 DUF3924 NPIP DUF4116 DUF4187
Motif
Other DBs
NCBI-GeneID: 5523
NCBI-ProteinID: NP_002709
OMIM: 604944
HGNC: 9307
Ensembl: ENSG00000073711
Vega: OTTHUMG00000159766
Pharos: Q06190(Tbio)
UniProt: Q06190
Structure
PDB: 

Position
3q22.2-q22.3
AA seq 1150 aa AA seqDB search
MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPV
SQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFA
SGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSS
SVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCS
EDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSG
NNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNS
RKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEE
SDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNL
PKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFL
NSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIED
FAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQT
PEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPD
TCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTA
QSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPE
FHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHF
YVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYAD
FVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHD
LLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDG
PEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEK
CGKLQSVDEE
NT seq 3453 nt NT seq  +upstreamnt  +downstreamnt
atggcagcaacttacagacttgtggttagtactgtgaaccactacagcagcgtggtgata
gaccggcgttttgaacaagctatacattattgcactggaacctgccacaccttcacacat
ggaattgactgcattgtggtacaccatagtgtttgtgcagacctcttgcacatccctgtg
tctcagttcaaagatgcagatctgaactctatgtttctaccccatgaaaatgggctttct
tcggctgaaggagactatccccaacaggccttcacaggcatacccagggtcaagagagga
tctacatttcagaatacctacaacttaaaggatattgcaggagaagcaatcagttttgcc
agtgggaaaataaaagaattttcctttgaaaaactcaaaaactctaaccatgcagcttac
agaaagggaaggaaagttaagtctgactcatttaataggaggtcagttgatttggacttg
ctttgtggccattataacaacgatgggaacgccccatcctttggtttactgcggagttcc
tcagttgaggaaaaacctttgtctcatagaaactcactggatacgaacctgacttccatg
tttcttcaaaacttttctgaagaagacttggttactcagattttggaaaaacataaaata
gataatttttcttctgggacagacataaagatgtgcttggacatcttattgaaatgctcc
gaggatttaaaaaaatgcacagacatcataaaacaatgcataaagaaaaaatcagggagt
agcatcagtgaaggaagtggtaatgatacaatttctagctctgaaactgtctatatgaat
gtaatgaccaggttagcatcctatctgaaaaagttaccatttgaattcatgcagtctggg
aataatgaggctctagatttaacagaactgatcagtaatatgcctagcttacaactgact
cccttctccccagtgtttggcactgaacaaccccctaaatatgaagatgttgtccagctc
tcagcttctgactctggacgatttcaaactattgaattgcaaaatgacaagcctaattct
aggaagatggacactgtacaatccattccaaacaactccacaaattccttatataactta
gaggtaaatgatcctagaactctaaaagctgtccaggtccaatcacagtcattaaccatg
aatcctttagaaaatgtttcttctgacgacttaatggaaactctttatattgaagaagag
tcagatggaaagaaagcattagataaaggacaaaagacagagaatggacctagtcatgag
ttattaaaggtaaatgaacatagagcagaatttccagaacatgctactcatcttaaaaaa
tgccccaccccaatgcaaaatgaaattggtaagatatttgagaaatcatttgttaatcta
cctaaggaagactgtaaatcaaaagtttctaaatttgaagagggagaccagagagatttt
acaaattccagtagccaggaagagatagataaattgttaatggatttggaatctttttca
cagaagatggagacctctctaagagagccacttgcgaagggtaaaaactctaatttttta
aatagtcacagtcagttgaccggtcagacccttgtagatcttgagcctaaatctaaagtc
tcttcacccatagaaaaagtctcaccttcctgtctaacaaggattattgaaaccaatgga
cacaaaatagaggaagaggatcgagccctcttactgcgaatcctggaaagcattgaagac
tttgctcaagaactagttgaatgcaaatcaagcagagggagcctatcacaagaaaaggaa
atgatgcaaattctacaggaaaccttgacaacttcctcccaggccaatttatcagtctgt
agaagtcctgttggtgataaagccaaagatactacttcagcagttttgattcagcagact
ccagaggtgatcaagattcaaaataaaccagaaaagaaacctggaacaccactcccacct
ccagccacctctccaagtagtccccgacctctctccccggttccccatgtgaataatgtt
gtgaatgcgccattgtccataaacattccacggttctactttcctgaaggactcccagat
acctgtagtaatcatgaacaaactctaagcagaattgaaactgctttcatggatattgaa
gaacagaaagcagacatttatgaaatggggaaaattgcaaaggtctgtggctgtcctctc
tattggaaagcccccatgttcagggctgcagggggagagaagacaggatttgtgacagca
cagtcattcattgccatgtggagaaagttgctgaataaccatcatgatgatgcctctaaa
ttcatctgtcttctagcaaagcccaactgcagctctctagaacaggaggatttcatccct
ctacttcaggatgtggtggatacccaccctggtctcacgttcctgaaagatgctccagaa
ttccactcccgctacatcaccacggttattcagagaatattctacacagtcaacagatct
tggagtggaaaaattacttcgacagagataagaaaaagcaactttttgcaaaccctagca
cttttggaagaagaggaagatataaaccaaattacagattacttctcctatgaacatttc
tatgttatttattgtaaattctgggaactagatactgatcacgacctctacatcagccag
gccgatctgtctcgatacaatgaccaggcttcatcaagcaggattattgaaaggatattc
tctggtgcagtaacaaggggaaaaacaatacagaaagagggaagaatgagctatgcagat
tttgtttggtttttgatctctgaagaagacaaaaggaatcctaccagcattgagtattgg
ttccgctgcatggatgtggatggagacggtgtactctccatgtatgagctggagtacttc
tatgaggagcagtgtgaacggatggaagccatgggaattgagcccttgccattccatgat
ttactgtgccagatgcttgacctagtgaagccagctgttgatggcaaaataactctaaga
gatctgaagaggtgcagaatggctcacatcttctatgacactttctttaatctggagaaa
tacttagaccatgaacagagagatccctttgcggtccagaaggatgttgagaacgatggg
cctgagccctcagactgggaccggtttgccgctgaggagtatgagacgcttgttgcagag
gaatctgcccaagcacaattccaggaaggctttgaagattatgaaacagatgaacctgcc
tctccctctgaatttggaaacaaaagcaataaaatattaagtgcaagccttccagagaaa
tgtggaaagcttcaatcagtggatgaagaatag

KEGG   Homo sapiens (human): 5525Help
Entry
5525              CDS       T01001                                 

Gene name
PPP2R5A, B56A, B56alpha, PR61A
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B'alpha
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5525 (PPP2R5A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5525 (PPP2R5A)
   04151 PI3K-Akt signaling pathway
    5525 (PPP2R5A)
   04152 AMPK signaling pathway
    5525 (PPP2R5A)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5525 (PPP2R5A)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5525 (PPP2R5A)
  09156 Nervous system
   04728 Dopaminergic synapse
    5525 (PPP2R5A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5525 (PPP2R5A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5525 (PPP2R5A)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5525 (PPP2R5A)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5525 (PPP2R5A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5525 (PPP2R5A)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: B56 Sec7_N
Motif
Other DBs
NCBI-GeneID: 5525
NCBI-ProteinID: NP_006234
OMIM: 601643
HGNC: 9309
Ensembl: ENSG00000066027
Vega: OTTHUMG00000036750
Pharos: Q15172(Tchem)
UniProt: Q15172
Position
1q32.3
AA seq 486 aa AA seqDB search
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLK
DATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAY
SDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIA
KRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYET
EHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFL
EKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCV
SSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLK
TLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSIL
SNTSAE
NT seq 1461 nt NT seq  +upstreamnt  +downstreamnt
atgtcgtcgtcgtcgccgccggcgggggctgccagcgccgccatctcggcctcggagaaa
gtggacggcttcacccggaaatcggtccgcaaggcgcagaggcagaagcgctcccagggc
tcgtcgcagtttcgcagccagggcagccaggcagagctgcacccgctgccccagctcaaa
gatgccacttcaaatgaacaacaagagcttttctgtcagaagttgcagcagtgttgtata
ctgtttgatttcatggactctgtttcagacttgaagagcaaagaaattaaaagagcaaca
ctgaatgaactggttgagtatgtttcaactaatcgtggtgtaattgttgaatcagcgtat
tctgatatagtaaaaatgatcagtgctaacatcttccgtacacttcctccaagtgataat
ccagattttgatccagaagaggatgaacccacgcttgaggcctcttggcctcacatacag
ttggtatatgaattcttcttgagatttttggagagccctgatttccagcctagcattgca
aaacgatacattgatcagaaattcgtacaacagctcctggagctttttgatagtgaagat
cccagagaacgtgacttcctgaagactgttctgcaccgaatttatgggaaatttcttgga
ttaagagcattcatcagaaaacaaattaacaacattttcctcaggtttatatatgaaaca
gaacatttcaatggtgttgctgaacttcttgaaatattaggaagtattatcaatggcttt
gcattgccactgaaagcagaacataaacaatttctaatgaaggttcttattcctatgcat
actgcaaaaggattagctttgtttcatgctcagctagcatattgtgttgtacagttcctg
gagaaagatacaacactaacagagccagtgatcagaggactgctgaaattttggccaaaa
acctgcagtcagaaagaggtgatgtttttaggagaaattgaagaaatcttagatgtcatt
gaaccaacacagttcaaaaaaattgaagagccacttttcaagcagatatccaagtgtgta
tccagttctcattttcaggttgcagaaagggcattgtacttctggaataacgaatatatt
cttagtttgattgaggagaacattgataaaattctgccaattatgtttgccagtttgtac
aaaatttccaaagaacactggaatccgaccattgtagcactggtatacaatgtgctgaaa
accctaatggaaatgaatggcaagcttttcgatgaccttactagctcatacaaagctgaa
agacagagagagaaaaagaaggaattggaacgtgaagaattatggaaaaaattagaggag
ctaaagctaaagaaagctctagaaaaacagaatagtgcttacaacatgcacagtattctc
agcaatacaagtgccgaataa

KEGG   Homo sapiens (human): 5526Help
Entry
5526              CDS       T01001                                 

Gene name
PPP2R5B, B56B, B56beta, PR61B
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B'beta
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5526 (PPP2R5B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5526 (PPP2R5B)
   04151 PI3K-Akt signaling pathway
    5526 (PPP2R5B)
   04152 AMPK signaling pathway
    5526 (PPP2R5B)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5526 (PPP2R5B)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5526 (PPP2R5B)
  09156 Nervous system
   04728 Dopaminergic synapse
    5526 (PPP2R5B)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5526 (PPP2R5B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5526 (PPP2R5B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5526 (PPP2R5B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5526 (PPP2R5B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5526 (PPP2R5B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: B56 FTCD_C
Motif
Other DBs
NCBI-GeneID: 5526
NCBI-ProteinID: NP_006235
OMIM: 601644
HGNC: 9310
Ensembl: ENSG00000068971
Vega: OTTHUMG00000150043
Pharos: Q15173(Tbio)
UniProt: Q15173 A0A024R593
Position
11q13.1
AA seq 497 aa AA seqDB search
METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELT
PLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGV
LIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPD
FQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFL
RFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAY
CVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFK
QVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSL
IYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQGTQGAKE
APLQRLTPQVAASGGQS
NT seq 1494 nt NT seq  +upstreamnt  +downstreamnt
atggagacgaagctgccccctgcaagcacccccactagcccctcctcccccgggctgtcg
cctgtgcccccacccgacaaggtggacggcttctcccgccgttccctccgcagagcccgg
ccccgccgctcccacagctcctctcagttccgctatcagagcaaccagcaagagctcaca
ccgctgcccctgctcaaagatgtgccggcttccgagctgcacgagctgctgagccggaag
ctggcccagtgtggggtgatgtttgacttcttggactgtgtggccgacctcaaggggaag
gaggtgaagcgggcagccctcaacgagctggtggagtgtgtggggagcacccggggtgtc
ctcatcgagcccgtctacccagacatcatccgcatgatctcagtgaatatcttccggact
ctgccgcccagtgagaaccctgaatttgaccctgaagaggatgagcccaatcttgagcct
tcgtggccacacctgcagctggtatatgagtttttcctgcgtttcttggagagcccagac
ttccagccctccgtggccaagagatatgtggatcaaaagtttgtcctgatgctcctggag
ctatttgatagtgaggatccccgggagcgtgagtacctcaagaccatcctgcaccgggtc
tatggcaagttcctgggtctccgggcctacatccgcaaacagtgcaaccacatcttcctc
cggttcatctatgaattcgagcacttcaatggtgtggctgagctgctggagatcctagga
agcatcatcaatggctttgcgctgcccctgaagacggagcacaagcagttcctggttcgc
gtcctgatccccctgcactctgtcaagtcgctgtctgtcttccatgcccagctggcatac
tgtgtggtgcagttcctggagaaggatgccactctgacagagcacgtgatccgggggctg
ctcaaatactggccaaaaacctgcacccagaaggaggtgatgtttctgggggagatggaa
gagattcttgatgtcatcgagccctcccagtttgtgaagatccaggagcccctttttaag
caggtggctcgctgtgtttccagcccccatttccaggttgcagagcgggctctgtatttc
tggaacaatgagtatatcctaagcctcattgaggacaactgccacactgtgctgcctgct
gtgtttgggaccctctaccaagtctccaaggagcactggaaccaaaccatcgtatcactg
atctacaatgtgctcaagaccttcatggagatgaatgggaagctgtttgatgagctcaca
gcctcctacaagctggaaaagcagcaggagcagcagaaggcccaggagcgtcaggagtta
tggcaaggtctggaggagctgcggctacgccggctacaggggacccagggggccaaggag
gcccccctccagcggcttacaccccaggtggccgccagtgggggtcagagctag

KEGG   Homo sapiens (human): 5527Help
Entry
5527              CDS       T01001                                 

Gene name
PPP2R5C, B56G, B56gamma, PR61G
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B'gamma
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5527 (PPP2R5C)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5527 (PPP2R5C)
   04151 PI3K-Akt signaling pathway
    5527 (PPP2R5C)
   04152 AMPK signaling pathway
    5527 (PPP2R5C)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5527 (PPP2R5C)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5527 (PPP2R5C)
  09156 Nervous system
   04728 Dopaminergic synapse
    5527 (PPP2R5C)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5527 (PPP2R5C)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5527 (PPP2R5C)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5527 (PPP2R5C)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5527 (PPP2R5C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5527 (PPP2R5C)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: B56 MvaI_BcnI DUF1616
Motif
Other DBs
NCBI-GeneID: 5527
NCBI-ProteinID: NP_002710
OMIM: 601645
HGNC: 9311
Ensembl: ENSG00000078304
Vega: OTTHUMG00000171597
Pharos: Q13362(Tbio)
UniProt: Q13362
Structure
PDB: 

Position
14q32.31
AA seq 524 aa AA seqDB search
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPL
SDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDP
EEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERD
FLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLK
EEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPK
EVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLIS
DNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEK
LKMKEREEAWVKIENLAKANPQYTVYSQASTMSIPVAMETDGPLFEDVQMLRKTVKDEAH
QAQKDPKKDRPLARRKSELPQDPHTKKALEAHCRADELASQDGR
NT seq 1575 nt NT seq  +upstreamnt  +downstreamnt
atgttgacatgtaataaagcgggcagcaggatggtggtggatgcggccaactccaatggg
cctttccagcccgtggtccttctccatattcgagatgttcctcctgctgatcaagagaag
ctttttatccagaagttacgtcagtgttgcgtcctctttgactttgtttctgatccacta
agtgacctaaagtggaaggaagtaaaacgagctgctttaagtgaaatggtagaatatatc
acccataatcggaatgtgatcacagagcctatttacccagaagtagtccatatgtttgca
gttaacatgtttcgaacattaccaccttcctccaatcctacgggagcggaatttgacccg
gaggaagatgaaccaacgttagaagcagcctggcctcatctacagcttgtttatgaattt
ttcttaagatttttagagtctccagatttccaacctaatatagcgaagaaatatattgat
cagaagtttgtattgcagcttttagagctctttgacagtgaagatcctcgggagagagat
tttcttaaaaccacccttcacagaatctatgggaaattcctaggcttgagagcttacatc
agaaaacagataaataatatattttataggtttatttatgaaacagagcatcataatggc
atagcagagttactggaaatattgggaagtataattaatggatttgccttaccactaaaa
gaagagcacaagattttcttattgaaggtgttactacctttgcacaaagtgaaatctctg
agtgtctaccatccccagctggcatactgtgtagtgcagtttttagaaaaggacagcacc
ctcacggaaccagtggtgatggcacttctcaaatactggccaaagactcacagtccaaaa
gaagtaatgttcttaaacgaattagaagagattttagatgtcattgaaccatcagaattt
gtgaagatcatggaacccctcttccggcagttggccaaatgtgtctccagcccacacttc
caggtggcagagcgagctctctattactggaataatgaatacatcatgagtttaatcagt
gacaacgcagcgaagattctgcccatcatgtttccttccttgtaccgcaactcaaagacc
cattggaacaagacaatacatggcttgatatacaacgccctgaagctcttcatggagatg
aaccaaaagctatttgatgactgtacacaacagttcaaagcagagaaactaaaagagaag
ctaaaaatgaaagaacgggaagaagcatgggttaaaatagaaaatctagccaaagccaat
ccccagtacacagtgtatagtcaagccagcaccatgagcattccggttgcaatggagaca
gatgggcctttatttgaagatgtgcagatgctgagaaagacagtgaaggacgaggctcat
caggcacagaaagatccgaagaaggaccgtcctcttgcacgccgcaagtccgagctgcct
caggacccccacaccaagaaagccttggaagctcactgcagggccgatgagctggcctcc
caggacggccgctag

KEGG   Homo sapiens (human): 5528Help
Entry
5528              CDS       T01001                                 

Gene name
PPP2R5D, B56D, B56delta, MRD35
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B'delta
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5528 (PPP2R5D)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5528 (PPP2R5D)
   04151 PI3K-Akt signaling pathway
    5528 (PPP2R5D)
   04152 AMPK signaling pathway
    5528 (PPP2R5D)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5528 (PPP2R5D)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5528 (PPP2R5D)
  09156 Nervous system
   04728 Dopaminergic synapse
    5528 (PPP2R5D)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5528 (PPP2R5D)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5528 (PPP2R5D)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5528 (PPP2R5D)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5528 (PPP2R5D)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5528 (PPP2R5D)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: B56 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 5528
NCBI-ProteinID: NP_006236
OMIM: 601646
HGNC: 9312
Ensembl: ENSG00000112640
Vega: OTTHUMG00000014716
Pharos: Q14738(Tbio)
UniProt: Q14738 A0A024RD11
Position
6p21.1
AA seq 602 aa AA seqDB search
MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEAQPQPQPQPQPQAQSQPPSSNKRPS
NSTPPPTQLSKIKYSGGPQIVKKERRQSSSRFNLSKNRELQKLPALKDSPTQEREELFIQ
KLRQCCVLFDFVSDPLSDLKFKEVKRAGLNEMVEYITHSRDVVTEAIYPEAVTMFSVNLF
RTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFV
LALLDLFDSEDPRERDFLKTILHRIYGKFLGLRAYIRRQINHIFYRFIYETEHHNGIAEL
LEILGSIINGFALPLKEEHKMFLIRVLLPLHKVKSLSVYHPQLAYCVVQFLEKESSLTEP
VIVGLLKFWPKTHSPKEVMFLNELEEILDVIEPSEFSKVMEPLFRQLAKCVSSPHFQVAE
RALYYWNNEYIMSLISDNAARVLPIMFPALYRNSKSHWNKTIHGLIYNALKLFMEMNQKL
FDDCTQQYKAEKQKGRFRMKEREEMWQKIEELARLNPQYPMFRAPPPLPPVYSMETETPT
AEDIQLLKRTVETEAVQMLKDIKKEKVLLRRKSELPQDVYTIKALEAHKRAEEFLTASQE
AL
NT seq 1809 nt NT seq  +upstreamnt  +downstreamnt
atgccctataaactgaaaaaggagaaggagccccccaaggttgccaaatgcacagccaag
cctagcagctcgggcaaggatggtggaggcgagaacactgaggaggcccagccgcagccc
cagccccagccccagccccaagcccagtctcagccaccgtcatccaacaagcgtcccagc
aatagcacgccgccccccacgcagctcagcaaaatcaagtactcaggggggccccagatt
gtcaagaaggagcgacggcaaagctcctcccgcttcaacctcagcaagaatcgggagctg
cagaagcttcctgccctgaaagattcgccaacccaggagcgggaggagctgtttatccag
aagctacgccagtgctgtgtcctctttgacttcgtgtcagacccactcagtgacctcaaa
ttcaaggaggtgaagcgggcaggactcaacgagatggtggagtacatcacccatagccgt
gatgttgtcactgaggccatttaccctgaggctgtcaccatgttttcagtgaacctcttc
cggacgctgccaccttcatcgaatcccacaggggctgagtttgacccagaggaagatgag
cccaccctggaagctgcttggccacatctccagctcgtgtatgagttcttcttacgtttc
cttgagtctcctgatttccagccaaacatagccaagaagtacatcgaccagaagtttgta
cttgctctcctagacctatttgacagtgaggatcctcgagagcgggacttcctcaagacc
attttgcatcgcatctatggcaagtttttggggctccgggcttatatccgtaggcagatc
aaccacatcttctacaggttcatctacgagacggagcatcacaacgggattgctgagctc
ctggagatcctgggcagcatcatcaatggctttgccctgccccttaaagaagagcacaag
atgttcctcatccgtgtcctacttccccttcacaaggtcaagtccctgagtgtctaccac
cctcagctggcatactgtgtggtacaattcctggagaaggagagcagtctgactgagccg
gtaattgtgggacttctcaagttttggcccaagacccacagccccaaggaggtgatgttc
ttgaatgagctggaggagattctggacgtcattgaaccttctgagttcagcaaagtgatg
gaacccctcttccgccagctggccaagtgtgtctctagcccccatttccaggtggcagag
cgtgctctctattactggaacaatgagtacatcatgagcctgataagtgacaatgctgcc
cgagtcctccccatcatgttccctgcactctacaggaactccaagagccactggaacaag
acaatccatggactgatctataatgccctgaagttgtttatggaaatgaatcagaagctg
tttgatgactgcacacaacaatacaaggcagagaagcagaagggccggttccgaatgaag
gaaagggaagagatgtggcaaaaaatcgaggagctggcccggcttaatccccagtatccc
atgttccgagcccctccaccactgccccctgtgtactcgatggagacagagacccccaca
gctgaggacatccagcttctgaagaggactgtggagactgaggctgttcagatgctaaaa
gacatcaagaaggagaaagtgctgctgcggaggaagtcggagctgccccaggacgtgtac
accatcaaggcactggaggcgcacaagcgggcggaagagttcctaactgccagccaggag
gctctctga

KEGG   Homo sapiens (human): 5529Help
Entry
5529              CDS       T01001                                 

Gene name
PPP2R5E, B56E, B56epsilon
Definition
(RefSeq) protein phosphatase 2 regulatory subunit B'epsilon
  KO
K11584  serine/threonine-protein phosphatase 2A regulatory subunit B'
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    5529 (PPP2R5E)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    5529 (PPP2R5E)
   04151 PI3K-Akt signaling pathway
    5529 (PPP2R5E)
   04152 AMPK signaling pathway
    5529 (PPP2R5E)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    5529 (PPP2R5E)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5529 (PPP2R5E)
  09156 Nervous system
   04728 Dopaminergic synapse
    5529 (PPP2R5E)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    5529 (PPP2R5E)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5529 (PPP2R5E)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5529 (PPP2R5E)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     5529 (PPP2R5E)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     5529 (PPP2R5E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: B56 Sec7_N SBF2 NAD1
Motif
Other DBs
NCBI-GeneID: 5529
NCBI-ProteinID: NP_001269108
OMIM: 601647
HGNC: 9313
Ensembl: ENSG00000154001
Vega: OTTHUMG00000140341
Pharos: Q16537(Tbio)
UniProt: Q16537
Position
14q23.2
AA seq 467 aa AA seqDB search
MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQP
ELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVS
CNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKF
VLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAE
LLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTE
PVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVA
ERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNST
MFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT
NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt
atgtcctcagcaccaactactcctccatcagtggataaagtagacggattttctcggaag
tccgtcagaaaagccagacagaagaggtcgcaaagttcctcacagtttaggtctcaaggc
aagcctattgagttaacacctctgccgctgctaaaagacgttccatcctcagagcagcct
gaactgttcctaaagaaacttcagcagtgctgtgtcatttttgacttcatggacacgcta
tctgatcttaaaatgaaagaatacaagcgctccactcttaatgaactggtggactacatt
acaataagcagaggctgtttgacagagcagacttaccctgaagtagttagaatggtatct
tgcaatatattcagaactctccctcctagtgacagcaatgaatttgatccagaagaagat
gaacctacccttgaggcatcgtggccacacttacagcttgtatatgaatttttcatacga
tttttggaaagccaagaattccaacccagcattgccaaaaaatatatagatcagaaattt
gtattacagcttctggagctatttgacagcgaagaccctcgggaacgggactacttaaaa
acagtcttacacagaatttatggcaagtttcttggtcttagagcatttatccgaaaacag
attaacaatatttttctaaggtttgtttatgaaacagaacacttcaatggtgtagctgaa
ctgctggaaatattaggaagtattatcaatggctttgctttacctcttaaggcagaacac
aaacagtttctggtgaaagtattgatccctttacacactgtcaggagcttatcactcttc
catgcacagctggcatattgtatagtacagtttctggagaaagatccttcactcacagaa
ccagttattagggggttaatgaaattttggcctaaaacatgtagtcaaaaagaggtcatg
ttccttggggaactggaagaaatattggatgtgattgaaccttcacaatttgttaaaatc
caagaacctttgtttaaacaaatcgccaagtgtgtatctagcccccattttcaggtggca
gaaagagcactctattattggaataatgaatacatcatgagtttgatagaagaaaactct
aacgtcatccttcccatcatgttttccagcctttataggatttcaaaagaacattggaat
ccggctattgtggcgttggtgtacaatgtgttgaaggcatttatggaaatgaacagcacc
atgtttgacgagctgacagccacatacaagtcagatcgtcagcgtgagaaaaagaaagaa
aaggagcgtgaagaattgtggaaaaaattggaggatctggagttaaagagaggtcttaga
cgtgatggaataattccaacttaa

KEGG   Homo sapiens (human): 55844Help
Entry
55844             CDS       T01001                                 

Gene name
PPP2R2D, B55D, B55delta, MDS026
Definition
(RefSeq) protein phosphatase 2 regulatory subunit Bdelta
  KO
K04354  serine/threonine-protein phosphatase 2A regulatory subunit B
Organism
hsa  Homo sapiens (human)
Pathway
hsa03015  mRNA surveillance pathway
hsa04071  Sphingolipid signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04152  AMPK signaling pathway
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04390  Hippo signaling pathway
hsa04530  Tight junction
hsa04728  Dopaminergic synapse
hsa05142  Chagas disease (American trypanosomiasis)
hsa05160  Hepatitis C
hsa05165  Human papillomavirus infection
Network
nt06114  PI3K signaling (virus)
nt06166  Human papillomavirus (HPV)
  Element
N00355  PP2A-AKT signaling pathway
N00356  HPV E7 to PP2A-AKT signaling patyway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    55844 (PPP2R2D)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    55844 (PPP2R2D)
   04071 Sphingolipid signaling pathway
    55844 (PPP2R2D)
   04151 PI3K-Akt signaling pathway
    55844 (PPP2R2D)
   04152 AMPK signaling pathway
    55844 (PPP2R2D)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    55844 (PPP2R2D)
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    55844 (PPP2R2D)
  09156 Nervous system
   04728 Dopaminergic synapse
    55844 (PPP2R2D)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    55844 (PPP2R2D)
   05165 Human papillomavirus infection
    55844 (PPP2R2D)
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    55844 (PPP2R2D)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    55844 (PPP2R2D)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    55844 (PPP2R2D)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     55844 (PPP2R2D)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     55844 (PPP2R2D)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Y_phosphatase2
Motif
Other DBs
NCBI-GeneID: 55844
NCBI-ProteinID: NP_060931
OMIM: 613992
HGNC: 23732
Ensembl: ENSG00000175470
Vega: OTTHUMG00000019277
Pharos: Q66LE6(Tdark)
UniProt: Q66LE6
Position
10q26.3
AA seq 453 aa AA seqDB search
MAGAGGGGCPAGGNDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVI
FQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLST
NDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFAN
AHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEF
HPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFS
HSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSD
SAIMTGSYNNFFRMFDRDTRRDVTLEASRESSKPRASLKPRKVCTGGKRRKDEISVDSLD
FNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN
NT seq 1362 nt NT seq  +upstreamnt  +downstreamnt
atggcaggagccggaggcggcggctgccccgcgggcggcaacgacttccagtggtgcttc
tcgcaggtcaagggggccatcgacgaggacgtggccgaagcggacatcatttccaccgtt
gagtttaattactctggagatcttcttgcaacaggagacaagggcggcagagttgttatt
tttcagcgtgaacaagagaataaaagccgccctcattctaggggagaatataatgtttac
agcacctttcaaagtcatgaaccggagtttgactatttgaaaagtctagaaattgaggaa
aaaattaataaaattaggtggttaccacaacagaatgctgctcattttctactgtctaca
aatgataaaactataaaattatggaaaataagtgaacgggataaaagagcagaaggttat
aacctgaaagacgaagatggaagacttcgagacccatttaggatcacggcgctacgggtc
ccaatattgaagcccatggatcttatggtagaagcgagtccacggcgaatttttgcaaat
gctcacacatatcatataaattccatttcagtaaatagtgatcatgaaacatatctttct
gcagatgacctgagaattaatttatggcacttagaaatcacagatagaagctttaacatc
gtggacatcaagcctgctaacatggaggagctgaccgaagtcatcactgcagccgagttc
cacccgcaccagtgcaacgtgttcgtctacagcagtagcaaagggaccatccgcctgtgt
gacatgcgctcctcggccctgtgcgacagacactccaagttttttgaagagcctgaagat
cccagcagtaggtccttcttctcagaaataatttcatccatatccgatgtaaaattcagt
catagtgggcggtacatgatgaccagagactacctgtcggtgaaggtgtgggacctcaac
atggagagcaggccggtggagacccaccaggtccacgagtacctgcgcagcaagctctgc
tctctctatgagaacgactgcatctttgacaagtttgagtgttgctggaacggttcggat
agcgccatcatgaccgggtcctataacaacttcttcaggatgtttgatagagacacgcgg
agggatgtgaccctggaggcctcgagagagagcagcaaaccgcgcgccagcctcaaaccc
cggaaggtgtgtacggggggtaagcggaggaaagacgagatcagtgtggacagtctggac
ttcaacaagaagatcctgcacacagcctggcaccccgtggacaatgtcattgccgtggct
gccaccaataacttgtacatattccaggacaaaatcaactag

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