KEGG T01001: 285242

Homo sapiens (human): 285242

Entry

285242            CDS       T01001

Symbol

HTR3E, 5-HT3-E, 5-HT3E, 5-HT3c1

Name

(RefSeq) 5-hydroxytryptamine receptor 3E

K04819

5-hydroxytryptamine receptor 3

Organism

hsa Homo sapiens (human)

Pathway

hsa04726

Serotonergic synapse

hsa04742

Taste transduction

Drug target

Alosetron (DG00046):

D02829<US> D07129

Azasetron (DG01521):

D01613 D07481

Batanopride hydrochloride:

D03060

Bemesetron:

D03073

Cilansetron (DG00047):

D03495 D03496

Clozapine:

D00283<JP/US>

Dazopride fumarate:

D03662

Dolasetron (DG00063):

D00725<US> D07867

Fabesetron hydrochloride:

D01838

Galdansetron hydrochloride:

D04294

Indisetron hydrochloride:

D02632

Itasetron (DG01240):

D04642 D09749

Lurosetron mesylate:

D04821

Mianserin (DG00951):

D01358<JP> D08216

Mirisetron maleate:

D05050

Mirtazapine (DG02838):

D00563<JP/US> D11056

Ondansetron (DG00060):

D00456<US> D00678<JP/US>

Palonosetron (DG00064):

D05343<JP/US> D07175

Pancopride:

D05348

Quipazine maleate:

D05685

Ramosetron (DG01239):

D02016<JP> D08466

Renzapride:

D06396

Tedatioxetine (DG01311):

D10170 D10171

Tropanserin hydrochloride:

D06253

Tropisetron (DG00062):

D02041 D02130

Vortioxetine (DG00965):

D10184 D10185<JP/US> D12544

Zacopride hydrochloride:

D06353

Zatosetron maleate:

D06358

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    285242 (HTR3E)
  09157 Sensory system
   04742 Taste transduction
    285242 (HTR3E)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    285242 (HTR3E)
Ion channels [BR:hsa04040]
Ligand-gated channels
  Serotonin (5-HT3)
   285242 (HTR3E)

SSDB

Motif

Pfam:

Neur_chan_LBD Neur_chan_memb

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Position

3:184097064..184106995

AA seq 456 aa
MEGSWFHRKRFSFYLLLGFLLQGRGVTFTINCSGFGQHGADPTALNSVFNRKPFRPVTNI
SVPTQVNISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGITKMSMAAKNL
WLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQNCTLTF
SSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYDQIVFY
VAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITLLLGYNVFLLMMSDLL
PTSGTPLIGVYFALCLSLMVGSLLETIFITHLLHVATTQPPPLPRWLHSLLLHCNSPGRC
CPTAPQKENKGPGLTPTHLPGVKEPEVSAGQMPGPAEAELTGGSEWTRAQREHEAQKQHS
VELWLQFSHAMDAMLFRLYLLFMASSIITVICLWNT

NT seq 1371 nt +upstreamnt +downstreamnt
atggaaggaagctggttccacaggaaaagattttccttctacctccttctcggttttctg
cttcaaggaaggggcgttactttcaccatcaattgctcagggtttggccagcacggggcg
gatcccactgctctgaattcagtgtttaatagaaagcccttccgtccggtcaccaacatc
agcgtccccacccaagtcaacatctccttcgcgatgtctgccatcctagatgtgaatgaa
cagctgcacctcttgtcatcattcctgtggctggaaatggtttgggataacccatttatc
agctggaacccagaggaatgtgagggcatcacgaagatgagtatggcagccaagaacctg
tggctcccagacattttcatcattgaactcatggatgtggataagaccccaaaaggcctc
acagcatatgtaagtaatgaaggtcgcatcaggtataagaaacccatgaaggtggacagt
atctgtaacctggacatcttctacttccccttcgaccagcagaactgcacactcaccttc
agctcattcctctacacagtggacagcatgttgctggacatggagaaagaagtgtgggaa
ataacagacgcatcccggaacatccttcagacccatggagaatgggagctcctgggcctc
agcaaggccaccgcaaagttgtccaggggaggcaacctgtatgatcagatcgtgttctat
gtggccatcaggcgcaggcccagtctctatgtcataaaccttctcgtgcccagtggcttt
ctggttgccatcgatgccctcagcttctacctgccagtgaaaagtgggaatcgtgtccca
ttcaagataacgctcctgctgggctacaacgtcttcctgctcatgatgagtgacttgctc
cccaccagtggcacccccctcatcggtgtctacttcgccctgtgcctgtccctgatggtg
ggcagcctgctggagaccatcttcatcacccacctgctgcacgtggccaccacccagccc
ccacccctgcctcggtggctccactccctgctgctccactgcaacagcccggggagatgc
tgtcccactgcgccccagaaggaaaataagggcccgggtctcacccccacccacctgccc
ggtgtgaaggagccagaggtatcagcagggcagatgccgggccctgcggaggcagagctg
acagggggctcagaatggacaagggcccagcgggaacacgaggcccagaagcagcactca
gtggagctgtggttgcagttcagccacgcgatggacgccatgctcttccgcctctacctg
ctcttcatggcctcctctatcatcaccgtcatatgcctctggaacacctag

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