KEGG   Homo sapiens (human): 2887
Entry
2887              CDS       T01001                                 

Gene name
GRB10, GRB-IR, Grb-10, IRBP, MEG1, RSS
Definition
(RefSeq) growth factor receptor bound protein 10
  KO
K20064  growth factor receptor-bound protein 10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    2887 (GRB10)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2887 (GRB10)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    2887 (GRB10)
SSDB
Motif
Pfam: BPS SH2 RA CCD48 PH
Other DBs
NCBI-GeneID: 2887
NCBI-ProteinID: NP_001001549
OMIM: 601523
HGNC: 4564
Ensembl: ENSG00000106070
Vega: OTTHUMG00000150622
Pharos: Q13322(Tbio)
UniProt: Q13322
Structure
PDB: 
1NRV 3HK0

Position
7p12.1
AA seq 548 aa
MALAGCPDSFLHHPYYQDKVEQTPRSQQDPAGPGLPAQSDRLANHQEDDVDLEALVNDMN
ASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHILAV
RRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSK
VVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVESTMASE
SKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQEPRHLQLLADLEDSNIFS
LIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQN
YRIPQQRKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRS
TRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNP
KAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLK
HHCIRVAL
NT seq 1647 nt   +upstreamnt  +downstreamnt
atggctttagccggctgcccagattcctttttgcaccatccgtactaccaggacaaggtg
gagcagacacctcgcagtcaacaagacccggcaggaccaggactccccgcacagtctgac
cgacttgcgaatcaccaggaggatgatgtggacctggaagccctggtgaacgatatgaat
gcatccctggagagcctgtactcggcctgcagcatgcagtcagacacggtgcccctcctg
cagaatggccagcatgcccgcagccagcctcgggcttcaggccctcctcggtccatccag
ccacaggtgtccccgaggcagagggtgcagcgctcccagcctgtgcacatcctcgctgtc
aggcgccttcaggaggaagaccagcagtttagaacctcatctctgccggccatccccaat
ccttttcctgaactctgtggccctgggagcccccctgtgctcacgccgggttctttacct
ccgagccaggccgccgcaaagcaggatgttaaagtctttagtgaagatgggacaagcaaa
gtggtggagattctagcagacatgacagccagagacctgtgccaattgctggtttacaaa
agtcactgtgtggatgacaacagctggacactagtggagcaccacccgcacctaggatta
gagaggtgcttggaagaccatgagctggtggtccaggtggagagtaccatggccagtgag
agtaaatttctattcaggaagaattacgcaaaatacgagttctttaaaaatcccatgaat
ttcttcccagaacagatggttacttggtgccagcagtcaaatggcagtcaaacccagctt
ttgcaggaacccagacacctgcagctgctggccgacctggaggacagcaacatcttctcc
ctgatcgctggcaggaagcagtacaacgcccctacagaccacgggctctgcataaagcca
aacaaagtcaggaatgaaactaaagagctgaggttgctctgtgcagaggacgagcaaacc
aggacgtgctggatgacagcgttcagactcctcaagtatggaatgctcctttaccagaat
taccgaatccctcagcagaggaaggccttgctgtccccgttctcgacgccagtgcgcagt
gtctccgagaactccctcgtggcaatggatttttctgggcaaacaggacgcgtgatagag
aatccggcagaggcccagagcgcagccctggaggagggccacgcctggaggaagcgaagc
acacggatgaacatcctaggtagccaaagtcccctccacccttctaccctaagtacagtg
attcacaggacacagcactggtttcacgggaggatctccagggaggaatcccacaggatc
attaaacagcaagggctcgtggatgggctttttctcctccgtgacagccagagtaatcca
aaggcatttgtactcacactgtgtcatcaccagaaaattaaaaatttccagatcttacct
tgcgaggacgacgggcagacgttcttcagcctagatgacgggaacaccaaattctctgac
ctgatccagctggttgacttttaccagctgaacaaaggagtcctgccttgcaaactcaag
caccactgcatccgagtggccttatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (49)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (47)   
DNA sequence (84)   
   RefSeq(nuc) (48)   
   GenBank (18)   
   EMBL (18)   
Protein domain (5)   
   Pfam (5)   
All databases (162)   

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