KEGG   Homo sapiens (human): 2889
Entry
2889              CDS       T01001                                 
Symbol
RAPGEF1, C3G, GRF2
Name
(RefSeq) Rap guanine nucleotide exchange factor 1
  KO
K06277  Rap guanine nucleotide exchange factor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04510  Focal adhesion
hsa04722  Neurotrophin signaling pathway
hsa04910  Insulin signaling pathway
hsa05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    2889 (RAPGEF1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    2889 (RAPGEF1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    2889 (RAPGEF1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    2889 (RAPGEF1)
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    2889 (RAPGEF1)
SSDB
Motif
Pfam: RasGEF RasGEF_N
Other DBs
NCBI-GeneID: 2889
NCBI-ProteinID: NP_005303
OMIM: 600303
HGNC: 4568
Ensembl: ENSG00000107263
Pharos: Q13905(Tbio)
UniProt: Q13905
Structure
Position
9:complement(131576775..131740076)
AA seq 1077 aa
MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEG
YPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKV
LEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLANLIRWSDQVMLEGVNSE
DKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSSPASKPDGPAELPLTDRE
VEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPPPALPPKKRQSAPSPTRV
AVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKS
DEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQTAWNLSPLPESLGE
SGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRSAASQTADGSGCRVSYER
HPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVEFVGDFTAPESTGDPEKP
PPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKNKLLMEVYGFSDSFSGVD
SVQELAPPPALPPKQRQLEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSPDALESAQ
SEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFL
TTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVELTEEILK
LLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFH
SHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQ
EKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTL
IDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILD
SMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
NT seq 3234 nt   +upstreamnt  +downstreamnt
atggacacagactctcagcgttctcatctctcttccttcaccatgaagctgatggacaaa
ttccactcacccaaaatcaagagaacgccatcaaagaagggaaaaccagctgaggtgtcc
gtaaagattccagagaagcctgtgaacaaagaggcaacagacagatttctaccagagggc
taccctctccccttggatctggagcagcaggcagtagaatttatgtccaccagtgctgtg
gcttccaggtctcaaaggcagaagaacctgagctggctggaggagaaagagaaggaagtt
gtcagtgccctgcgctactttaagaccattgtggacaaaatggcaattgataagaaggta
ctggagatgcttccagggtcagccagcaaggtgctggaggccatcttacccctggtgcag
aacgatcctcgaattcagcacagctcagccctctcttcctgctatagccgagtgtaccaa
agcctcgccaacctcattcgctggtctgaccaagtgatgctggaaggcgtgaactcagaa
gacaaggagatggtgacgactgtgaagggggtcatcaaggctgtgctggatggagtgaag
gagctggtcaggctcaccatcgagaagcagggacgtccgtctccgacgagccccgtgaag
cccagttcccctgccagcaagcctgatggcccagcagagctccccctgacagaccgcgag
gtagagatcctaaacaagacgactgggatgtcacagtcaactgagctcctcccagatgcc
acggatgaagaggtcgcgccccccaagcctcctctgcctggcattcgggtggttgataat
agtcctccaccagcattgccacccaagaaaagacagtcggcgccgtcccctacccgagtg
gctgtggtggcccccatgagccgagccaccagtggctccagtttgcctgttggaatcaat
aggcaggattttgatgttgactgttacgcacagaggcgactgtcaggaggcagccactca
tatggtggagagtcgccccgcctctccccctgcagcagcataggcaagctcagcaagtca
gacgagcagctgtcctctctggacagggacagtgggcagtgctcccggaacacaagctgt
gaaacactagaccactatgatcccgactatgaattcctccagcaagacctctctaacgca
gaccagatacctcagcagacggcctggaaccttagcccgttgccagagtctttgggggag
tctgggtctccatttcttggccctcctttccagctgcctcttggcggccatccccagcca
gacggacctctggccccagggcagcagacagatacgccacctgctctccccgagaagaag
cgcaggagcgcagcctcccagacggcggacggctctggctgcagggtgtcctacgagcgg
catccctcgcagtatgacaacatctctggggaggacctgcagagcacagccccgatccca
tccgtcccctacgcgccctttgctgctattctgccctttcagcatggaggttcctcagcc
cctgtcgaatttgtgggtgattttactgctcctgagtcaaccggtgacccagaaaaacca
cctcctctaccagagaagaaaaacaaacacatgctggcctacatgcagttgctggaggac
tactcggagccgcagccctctatgttctaccagacgccacagaacgagcacatctaccag
cagaagaacaagctcctcatggaggtatacggcttcagcgactccttcagtggggtggac
tccgtgcaggagctggccccgccgcccgccctaccccccaagcagcggcagctggagcca
ccggctgggaaagacggacatcccagagatccctcagcggtcagcggcgtccctgggaag
gacagcagagacggcagtgagagggccccaaagtcaccagatgctctggagtcggctcag
tcggaggaggaagtggacgagctgtccctcattgaccacaacgaaattatgtccaggctg
acgctcaagcaggagggtgatgacgggccggacgtccgcggaggatctggggacatctta
ctggtccatgctactgagactgacaggaaagatttggtgttgtactgcgaggcattcctg
accacctacaggaccttcatctccccagaggagctcatcaagaagctgcagtacagatat
gagaaattctctccctttgccgacacattcaagaagcgcgtcagcaagaacacgttcttc
gtgctggtacgggtggtggatgagctctgcctggtggagttgacagaagagatcctgaag
ctgctgatggaactggtcttccgcctggtgtgcaatggggagctgagcctggcccgtgtg
ctccggaagaacatcctggacaaggtggaccagaagaagctactcaggtgtgccacctcc
agccagcccctggcagcccggggggtagcagccaggccggggaccttgcacgactttcac
agccatgagatagcggagcagctaacgctgctggatgctgagctcttctataaaatagag
attcctgaggttttgctttgggcaaaagagcagaatgaggagaagagccccaacttgacc
cagttcacggagcacttcaacaacatgtcctactgggtccggtccataatcatgttacag
gaaaaggcccaggacagggaacggctgctcttgaagttcatcaagatcatgaagcacttg
cggaagctgaataacttcaactcctacttggccatcctctctgccctggactcggcgccc
atccgcaggctggagtggcagaagcagacttcagagggcctggccgagtactgcacactg
atcgacagctcgtcctccttccgagcctaccgggccgccctctcggaggtggaaccgccg
tgcatcccgtacctggggctgatcctgcaggacctgaccttcgttcacctgggaaaccca
gactacatcgacgggaaagtgaacttctccaagcggtggcagcagttcaacatcctcgac
agcatgcgctgcttccagcaggcgcactatgacatgcggaggaacgacgacattataaac
ttcttcaatgacttcagtgaccacctggctgaggaggccctatgggaactgtctctgaaa
attaaacccaggaacataacaaggagaaaaacagaccgggaagagaagacctag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (31)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (29)   
DNA sequence (77)   
   RefSeq(nuc) (29)   
   GenBank (24)   
   EMBL (24)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (139)   

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