KEGG   Homo sapiens (human): 2916
Entry
2916              CDS       T01001                                 

Gene name
GRM6, CSNB1B, GPRC1F, MGLUR6, mGlu6
Definition
(RefSeq) glutamate metabotropic receptor 6
  KO
K04608  metabotropic glutamate receptor 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04072  Phospholipase D signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
Disease
H00787  Congenital stationary night blindness
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    2916 (GRM6)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    2916 (GRM6)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    2916 (GRM6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    2916 (GRM6)
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    2916 (GRM6)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     2916 (GRM6)
G protein-coupled receptors [BR:hsa04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   2916 (GRM6)
Motif
Pfam: ANF_receptor 7tm_3 NCD3G Peripla_BP_6
Other DBs
NCBI-GeneID: 2916
NCBI-ProteinID: NP_000834
OMIM: 604096
HGNC: 4598
Ensembl: ENSG00000113262
Vega: OTTHUMG00000130889
Pharos: O15303(Tbio)
UniProt: O15303
Position
5q35.3
AA seq 877 aa
MARPRRAREPLLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQL
KKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGR
GDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPE
LSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREA
GGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGH
FLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEF
WEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQ
ALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNG
SASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHC
EACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVAT
TTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLG
TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP
PHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFN
EAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKT
YVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHK
NT seq 2634 nt   +upstreamnt  +downstreamnt
atggcgcggccccggagagcccgggagccgctgctcgtggcgctgctgccgctggcgtgg
ctggcgcaggcgggcctggcgcgcgcggcgggctctgtgcgcctggcgggcggcctgacg
ctgggcggcctgttcccggtgcacgcgcggggcgcggcgggccgggcgtgcgggcagctg
aagaaggagcagggcgtgcaccggctggaggccatgctgtacgcgctggaccgcgtcaac
gccgaccccgagctgctgcccggcgtgcgcctgggcgcgcggctgctggacacctgctcg
cgggacacctacgcgctggagcaggcgctgagcttcgtgcaggcgctgatccgcggccgc
ggcgacggcgacgaggtgggcgtgcgctgcccgggaggcgtccctccgctgcgccccgcg
ccccccgagcgcgtcgtggccgtcgtgggcgcctcggccagctccgtctccatcatggtc
gccaacgtgctgcgcctgtttgcgataccccagatcagctatgcctccacagccccggag
ctcagcgactccacacgctatgacttcttctcccgggtggtgccacccgactcctaccag
gcgcaggccatggtggacatcgtgagggcactgggatggaactatgtgtccacgctggcc
tccgagggcaactatggcgaaagtggggttgaggccttcgttcagatctcccgagaggct
gggggggtctgtattgcccagtctatcaagattcccagggaaccaaagccaggagagttc
agcaaggtgatcaggagactcatggagacgcccaacgcccggggcatcatcatctttgcc
aatgaggatgacatcaggcgggtcctggaggcagctcgccaggccaacctgaccggccac
ttcctgtgggtcggctcagacagctggggagccaagacctcacccatcttgagcctggag
gacgtggccgttggggccatcaccatcctgcccaaaagggcctccatcgacggatttgac
cagtacttcatgactcgatccctggagaacaaccgcaggaacatctggttcgccgagttc
tgggaagagaattttaactgcaaactgaccagctcaggtacccagtcagacgattccacc
cgcaaatgcacaggcgaggaacgcatcggccgggactccacctacgagcaggagggcaag
gtgcagtttgtgattgatgcggtgtacgccattgcccacgccctccacagcatgcaccag
gcgctctgccctgggcacacaggcctgtgcccggcgatggaacccactgatgggcggatg
cttctgcagtacattcgagctgtccgcttcaatggcagcgcaggaacccctgtgatgttc
aacgagaacggagatgcgcccgggcggtacgacatcttccagtaccaggcgaccaatggc
agtgccagcagtggcgggtaccaggcagtgggccagtgggcagagaccctcagactggat
gtggaggccctgcagtggtctggcgacccccacgaggtgccctcgtctctgtgcagcctg
ccctgcgggccgggggagcggaagaagatggtgaagggcgtcccctgctgttggcactgc
gaggcctgtgacgggtaccgcttccaggtggacgagttcacatgcgaggcctgtcctggg
gacatgaggcccacgcccaaccacacgggctgccgccccacacctgtggtgcgcctgagc
tggtcctccccctgggcagccccgccgctcctcctggccgtgctgggcatcgtggccact
accacggtggtggccaccttcgtgcggtacaacaacacgcccatcgtccgggcctcgggc
cgagagctcagctacgtcctcctcaccggcatcttcctcatctacgccatcaccttcctc
atggtggctgagcctggggccgcggtctgtgccgcccgcaggctcttcctgggcctgggc
acgaccctcagctactctgccctgctcaccaagaccaaccgtatctaccgcatctttgag
cagggcaagcgctcggtcacaccccctcccttcatcagccccacctcacagctggtcatc
accttcagcctcacctccctgcaggtggtggggatgatagcatggctgggggcccggccc
ccacacagcgtgattgactatgaggaacagcggacggtggaccccgagcaggccagaggg
gtgctcaagtgcgacatgtcggatctgtctctcatcggctgcctgggctacagcctcctg
ctcatggtcacgtgcacagtgtacgccatcaaggcccgtggcgtgcccgagaccttcaac
gaggccaagcccatcggcttcaccatgtacaccacctgcatcatctggctggcattcgtg
cccatcttctttggcactgcccagtcagctgaaaagatctacatccagacaaccacgcta
accgtgtccttgagcctgagtgcctcggtgtccctcggcatgctctacgtacccaaaacc
tacgtcatcctcttccatccagagcagaatgtgcagaagcgaaagcggagcctcaaggcc
acctccacggtggcagccccacccaagggcgaggatgcagaggcccacaagtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (51)   

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