KEGG   Homo sapiens (human): 2965
Entry
2965              CDS       T01001                                 

Gene name
GTF2H1, BTF2, P62, TFB1, TFIIH
Definition
(RefSeq) general transcription factor IIH subunit 1
  KO
K03141  transcription initiation factor TFIIH subunit 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa03420  Nucleotide excision repair
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    2965 (GTF2H1)
  09124 Replication and repair
   03420 Nucleotide excision repair
    2965 (GTF2H1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    2965 (GTF2H1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    2965 (GTF2H1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    2965 (GTF2H1)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIIH
     2965 (GTF2H1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TFIIH complex
     2965 (GTF2H1)
SSDB
Motif
Pfam: PH_TFIIH BSD
Other DBs
NCBI-GeneID: 2965
NCBI-ProteinID: NP_001135779
OMIM: 189972
HGNC: 4655
Ensembl: ENSG00000110768
Vega: OTTHUMG00000167690
Pharos: P32780(Tbio)
UniProt: P32780 A0A384MTQ8
Structure
PDB: 

Position
11p15.1
AA seq 548 aa
MATSSEEVLLIVKKVRQKKQDGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGK
AKIQLQLVLHAGDTTNFHFSNESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQE
DPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDG
CNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDRLNTGSK
DLFAECAKIDEKGLKTMVSLGVKNPLLDLTALEDKPLDEGYGISSVPSASNSKSIKENSN
AAIIKRFNHHSAMVLAAGLRKQEAQNEQTSEPSNMDGNSGDADCFQPAVKRAKLQESIEY
EDLGKNNSVKTIALNLKKSDRYYHGPTPIQSLQYATSQDIINSFQSIRQEMEAYTPKLTQ
VLSSSAASSTITALSPGGALMQGGTQQAINQMVPNDIQSELKHLYVAVGELLRHFWSCFP
VNTPFLEEKVVKMKSNLERFQVTKLCPFQEKIRRQYLSTNLVSHIEEMLQTAYNKLHTWQ
SRRLMKKT
NT seq 1647 nt   +upstreamnt  +downstreamnt
atggcaacctcatctgaagaagttttgctgattgtaaagaaagtgcgtcaaaagaagcag
gatggagctctgtacctcatggcagaaagaattgcttgggcacctgaaggcaaagataga
tttacaatcagccatatgtatgcagatattaaatgccagaaaattagtccagaaggaaaa
gctaaaattcagcttcagctggtcctacatgcaggggacacaactaacttccatttttcc
aatgaaagcacagcagtgaaagagcgagatgcagtaaaagaccttcttcagcagctgctg
cccaaattcaagaggaaagcaaataaagaactggaagagaagaacagaatgctgcaagaa
gatcctgttttgtttcagctttataaagaccttgttgtgagtcaagtgatcagtgctgag
gaattctgggccaatcgtttaaatgtgaatgcaacagatagttcttccacatccaatcat
aagcaggatgttggcatttctgctgcatttctggctgatgtccggccccaaactgatggc
tgtaacggtctaagatataatttaacttctgatatcattgagtccatatttaggacctat
ccagcagtaaaaatgaaatatgcagaaaatgttccccacaacatgacagagaaggaattc
tggacacgttttttccagtcccattattttcacagggatcggctgaatacagggtcaaag
gatctctttgcagaatgtgccaaaatagatgaaaaaggcctaaaaacaatggtttcatta
ggagtgaaaaacccactactagatttaacagctttggaagataaaccattagatgagggc
tatggcatttcctctgtgccatctgcttccaattctaaatccataaaagagaatagtaat
gctgccatcatcaagagatttaaccatcacagtgccatggtcctggcagctggactcaga
aaacaagaagcacaaaatgaacaaactagtgagcccagcaacatggatggaaattccgga
gatgcagactgctttcagccagcagtcaaaagggcgaaattacaagagtccattgaatat
gaagacttggggaaaaataattctgtaaaaacgattgcactaaacctcaagaagtcagat
aggtattatcatggtccaactccaatccagtcactacagtatgcaacaagtcaggacatt
attaattcttttcaaagtattagacaagaaatggaagcttatacacccaagttaactcag
gttctctcaagtagtgctgccagtagtaccatcacagcactgtcacctggaggggcactt
atgcagggaggaacacagcaagccataaaccagatggtgccaaatgatattcaatctgaa
ttgaaacacttatatgtagctgttggagaacttctacgacatttctggtcctgctttcct
gttaatacgccattcctagaagaaaaggtagtgaaaatgaaaagtaatttggaacgattc
caagttacgaagctctgtccattccaagaaaagattcggagacagtatttaagcacaaat
ttggtaagtcacatagaagagatgctccagacagcctacaacaagctccacacatggcag
tcacggcgtctgatgaagaaaacgtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (2)   
   Pfam (2)   
All databases (62)   

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