Entry |
|
Symbol |
HLA-G, MHC-G
|
Name |
(RefSeq) major histocompatibility complex, class I, G
|
KO |
|
Organism |
|
Pathway |
hsa04612 | Antigen processing and presentation |
hsa04650 | Natural killer cell mediated cytotoxicity |
hsa05163 | Human cytomegalovirus infection |
hsa05166 | Human T-cell leukemia virus 1 infection |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
hsa05168 | Herpes simplex virus 1 infection |
hsa05170 | Human immunodeficiency virus 1 infection |
|
Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06161 Human immunodeficiency virus 1 (HIV-1) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06165 Epstein-Barr virus (EBV) nt06166 Human papillomavirus (HPV) nt06167 Human cytomegalovirus (HCMV) nt06168 Herpes simplex virus 1 (HSV-1) nt06229 MHC presentation (cancer) |
Element |
N00184 | KSHV MIR1/2 to antigen processing and presentation by MHC class I molecules |
N00363 | Antigen processing and presentation by MHC class I molecules |
N00364 | HPV E5 to antigen processing and presentation by MHC class I molecules |
N00418 | HCMV US2/11 to antigen processing and presentation by MHC class I molecules |
N00419 | HCMV US3/10 to antigen processing and presentation by MHC class I molecules |
N00461 | HIV Nef to antigen processing and presentation by MHC class I molecules |
N00480 | EBV BILF1 to antigen processing and presentation by MHC class I molecules |
N00492 | HTLV-1 p12 to antigen processing and presentation by MHC class I molecules |
|
Disease |
|
Drug target |
Glatiramer acetate: | D04318<JP/US> |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
3135 (HLA-G)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
3135 (HLA-G)
04145 Phagosome
3135 (HLA-G)
09143 Cell growth and death
04218 Cellular senescence
3135 (HLA-G)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
3135 (HLA-G)
04612 Antigen processing and presentation
3135 (HLA-G)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
3135 (HLA-G)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
3135 (HLA-G)
05170 Human immunodeficiency virus 1 infection
3135 (HLA-G)
05168 Herpes simplex virus 1 infection
3135 (HLA-G)
05163 Human cytomegalovirus infection
3135 (HLA-G)
05167 Kaposi sarcoma-associated herpesvirus infection
3135 (HLA-G)
05169 Epstein-Barr virus infection
3135 (HLA-G)
05165 Human papillomavirus infection
3135 (HLA-G)
09163 Immune disease
05320 Autoimmune thyroid disease
3135 (HLA-G)
05330 Allograft rejection
3135 (HLA-G)
05332 Graft-versus-host disease
3135 (HLA-G)
09166 Cardiovascular disease
05416 Viral myocarditis
3135 (HLA-G)
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
3135 (HLA-G)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:hsa04147]
3135 (HLA-G)
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
3135 (HLA-G)
Exosome [BR:hsa04147]
Exosomal proteins
Proteins found in most exosomes
3135 (HLA-G)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
Antigens
3135 (HLA-G)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
Position |
6:29826474..29831021
|
AA seq |
338 aa
MVVMAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRF
DSDSACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQ
WMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQR
RAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILT
WQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQ
SSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSSD |
NT seq |
1017 nt +upstreamnt +downstreamnt
atggtggtcatggcgccccgaaccctcttcctgctgctctcgggggccctgaccctgacc
gagacctgggcgggctcccactccatgaggtatttcagcgccgccgtgtcccggcccggc
cgcggggagccccgcttcatcgccatgggctacgtggacgacacgcagttcgtgcggttc
gacagcgactcggcgtgtccgaggatggagccgcgggcgccgtgggtggagcaggagggg
ccggagtattgggaagaggagacacggaacaccaaggcccacgcacagactgacagaatg
aacctgcagaccctgcgcggctactacaaccagagcgaggccagttctcacaccctccag
tggatgattggctgcgacctggggtccgacggacgcctcctccgcgggtatgaacagtat
gcctacgatggcaaggattacctcgccctgaacgaggacctgcgctcctggaccgcagcg
gacactgcggctcagatctccaagcgcaagtgtgaggcggccaatgtggctgaacaaagg
agagcctacctggagggcacgtgcgtggagtggctccacagatacctggagaacgggaag
gagatgctgcagcgcgcggacccccccaagacacacgtgacccaccaccctgtctttgac
tatgaggccaccctgaggtgctgggccctgggcttctaccctgcggagatcatactgacc
tggcagcgggatggggaggaccagacccaggacgtggagctcgtggagaccaggcctgca
ggggatggaaccttccagaagtgggcagctgtggtggtgccttctggagaggagcagaga
tacacgtgccatgtgcagcatgaggggctgccggagcccctcatgctgagatggaagcag
tcttccctgcccaccatccccatcatgggtatcgttgctggcctggttgtccttgcagct
gtagtcactggagctgcggtcgctgctgtgctgtggagaaagaagagctcagattga |