KEGG   Homo sapiens (human): 3195
Entry
3195              CDS       T01001                                 
Symbol
TLX1, HOX11, TCL3
Name
(RefSeq) T cell leukemia homeobox 1
  KO
K09340  T-cell leukemia homeobox protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00144  TLX1 rearrangement to transcriptional repression
Disease
H00002  T-cell acute lymphoblastic leukemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    3195 (TLX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3195 (TLX1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Helix-turn-helix
   Homeo domain ANTP: NKL
    3195 (TLX1)
SSDB
Motif
Pfam: Homeodomain Homez Homeobox_KN
Other DBs
NCBI-GeneID: 3195
NCBI-ProteinID: NP_005512
OMIM: 186770
HGNC: 5056
Ensembl: ENSG00000107807
UniProt: P31314
Position
10:101131300..101137789
AA seq 330 aa
MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGG
GSAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS
GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESN
RRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKM
TDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQEAFQKSLAQPLPADPLCVHN
SSLFALQNLQPWSDDSTKITSVTSVASACE
NT seq 993 nt   +upstreamnt  +downstreamnt
atggagcacctgggtccgcaccacctccacccgggtcacgcagagcccattagcttcggc
atcgaccagatcctcaacagcccggaccagggtggctgcatgggacccgcctcgcgcctc
caggacggagaatacggccttggctgcttggtcggaggcgcctacacttacggcggcggg
ggctccgcggccgcgacgggggctggaggagcgggggcctatggtactggaggtcccggc
ggccccggaggcccggcaggcggcggcggcgcctgcagcatgggtcctctgaccggctcc
tacaacgtgaacatggccttggcaggcggccccggtcctggcggcggcggcggcagcagc
ggcggtgccggggcactcagcgctgcgggggtaatccgggtgccggcacacaggccgctc
gccggagccgtggcccacccccagcccctggccaccggcttgcccaccgtgccctctgtg
cctgccatgccgggcgtcaacaacctcactggcctcaccttcccctggatggagagtaac
cgcagatacacaaaggacaggttcacaggtcacccctatcagaaccggacgccccccaag
aagaagaagccgcgcacgtccttcacacgcctgcagatctgcgagctggagaagcgcttc
caccgccagaagtacctggcctcggccgagcgcgccgccctggccaaggcgctcaaaatg
accgatgcgcaggtcaaaacctggttccagaaccggcggacaaagtggagacggcagact
gcggaggaacgggaggccgagaggcagcaagcgaaccgcatcctcctgcagttgcagcag
gaggccttccagaagagcctggcacagccgctgcccgctgaccctctgtgcgtgcacaac
tcgtcgctcttcgccctgcagaatctgcagccgtggtctgacgactcgaccaaaatcact
agcgtcacgtcggtggcgtcggcctgcgagtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (10)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (14)   
   RefSeq(nuc) (4)   
   GenBank (5)   
   EMBL (5)   
Protein domain (3)   
   Pfam (3)   
All databases (34)   

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