KEGG   Homo sapiens (human): 3305Help
Entry
3305              CDS       T01001                                 

Gene name
HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t
Definition
(RefSeq) heat shock protein family A (Hsp70) member 1 like
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
hsa04010  MAPK signaling pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04144  Endocytosis
hsa04213  Longevity regulating pathway - multiple species
hsa04612  Antigen processing and presentation
hsa04915  Estrogen signaling pathway
hsa05134  Legionellosis
hsa05145  Toxoplasmosis
hsa05162  Measles
hsa05164  Influenza A
hsa05169  Epstein-Barr virus infection
Module
hsa_M00353  Spliceosome, Prp19/CDC5L complex
hsa_M00355  Spliceosome, 35S U5-snRNP
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    3305 (HSPA1L)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3305 (HSPA1L)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3305 (HSPA1L)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    3305 (HSPA1L)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    3305 (HSPA1L)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3305 (HSPA1L)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    3305 (HSPA1L)
 09160 Human Diseases
  09171 Infectious diseases: Bacterial
   05134 Legionellosis
    3305 (HSPA1L)
  09172 Infectious diseases: Viral
   05162 Measles
    3305 (HSPA1L)
   05164 Influenza A
    3305 (HSPA1L)
   05169 Epstein-Barr virus infection
    3305 (HSPA1L)
  09174 Infectious diseases: Parasitic
   05145 Toxoplasmosis
    3305 (HSPA1L)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3305 (HSPA1L)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    3305 (HSPA1L)
   03009 Ribosome biogenesis [BR:hsa03009]
    3305 (HSPA1L)
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3305 (HSPA1L)
   04131 Membrane trafficking [BR:hsa04131]
    3305 (HSPA1L)
   03051 Proteasome [BR:hsa03051]
    3305 (HSPA1L)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3305 (HSPA1L)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3305 (HSPA1L)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3305 (HSPA1L)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    3305 (HSPA1L)
 Complex C
   Prp19-CDC5 complex
    3305 (HSPA1L)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic Type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    3305 (HSPA1L)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP70 / DNAK
   3305 (HSPA1L)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    3305 (HSPA1L)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3305 (HSPA1L)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3305 (HSPA1L)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    3305 (HSPA1L)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3305 (HSPA1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HSP70 MreB_Mbl FGGY_C Radial_spoke_3
Motif
Other DBs
NCBI-GeneID: 3305
NCBI-ProteinID: NP_005518
OMIM: 140559
HGNC: 5234
Ensembl: ENSG00000204390
Vega: OTTHUMG00000031208
Pharos: P34931(Tbio)
UniProt: P34931 A0A1U9X7W7
Structure
PDB: 

Position
6p21.33
AA seq 641 aa AA seqDB search
MATAKGIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQ
VAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEE
ISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTA
AAIAYGLDKGGQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLV
SHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSIT
RARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRD
LNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGLETAGGVMTALIKRNS
TIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRGVPQIEVTF
DIDANGILNVTATDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAEDEVQREKIAA
KNALESYAFNMKSVVSDEGLKGKISESDKNKILDKCNELLSWLEVNQLAEKDEFDHKRKE
LEQMCNPIITKLYQGGCTGPACGTGYVPGRPATGPTIEEVD
NT seq 1926 nt NT seq  +upstreamnt  +downstreamnt
atggctactgccaagggaatcgccataggcatcgacctgggcaccacctactcctgtgtg
ggggtgttccagcacggcaaggtggagatcatcgccaacgaccagggcaaccgcaccacc
cccagctacgtggccttcacagacaccgagcggctcattggggatgcggccaagaaccag
gtagcaatgaatccccagaacactgtttttgatgctaaacgtctgatcggcaggaaattt
aatgatcctgttgtacaagcagatatgaaactttggccttttcaagtgattaatgaagga
ggcaagcccaaagtccttgtgtcctacaaaggggagaataaagctttctaccctgaggaa
atctcttcgatggtattgactaagttgaaggagactgctgaggcctttttgggccaccct
gtcaccaatgcagtgattaccgtgccagcctatttcaatgactctcaacgtcaggctact
aaggatgcaggtgtgattgctggacttaatgtgctaagaatcatcaatgagcccacggct
gctgccattgcctatggtttagataaaggaggtcaaggagaacgacatgtcctgattttt
gatctgggtggaggcacatttgatgtgtcaattctgaccatagatgatgggatttttgag
gtaaaggccactgctggggacactcacctgggtggggaggactttgacaacaggcttgtg
agccacttcgtggaggagttcaagaggaaacacaaaaaggacatcagccagaacaagcga
gccgtgaggcggctgcgcaccgcctgcgagagggccaagaggaccctgtcgtccagcacc
caggccaacctagaaattgattcactttatgaaggcattgacttctatacatccatcacc
agagctcgatttgaagagttgtgtgcagacctgtttaggggtaccctggagcctgtagaa
aaagcgcttcgggatgccaagatggataaggctaaaatccatgacattgttttagtaggg
ggctccacccgcatccccaaggtgcagcggctgcttcaggactacttcaatggacgtgat
ctcaacaagagcatcaaccctgatgaggccgtagcatatggggctgcggtacaagcagcc
atcctgatgggggacaagtctgagaaggtacaggacctgctgctgctggacgtggctccc
ctgtccctggggctggagacggctgggggcgtgatgactgccctgataaagcgcaactcc
accatccccaccaagcagacacagattttcaccacctactctgacaaccaacccggggtg
ctgatccaggtgtatgagggcgagagggccatgacaaaggacaacaacctgctggggcgg
tttgacctgactggaatccctccagcacccaggggagttcctcagatcgaggtgacgttt
gacattgatgccaatggtattctcaatgtcacagccacggacaagagcaccggcaaggtg
aacaagatcaccatcaccaatgacaagggccgcctgagcaaggaggagattgagcgcatg
gttctggatgctgagaaatataaagctgaagatgaggtccagagggagaaaattgctgca
aagaatgccttagaatcctatgcttttaacatgaagagtgttgtgagtgatgaaggtttg
aagggcaagattagtgagtctgataaaaataaaatattggataaatgcaacgagctcctt
tcgtggctggaggtcaatcaactggcagagaaagatgagtttgatcataagagaaaggaa
ttggagcagatgtgtaaccctatcatcacaaaactctaccaaggaggatgcactgggcct
gcctgcggaacagggtatgtgcctggaaggcctgccacaggccccacaattgaagaagta
gattaa

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