KEGG   Homo sapiens (human): 3320
Entry
3320              CDS       T01001                                 
Symbol
HSP90AA1, EL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp103, Hsp89, Hsp90, LAP-2, LAP2
Name
(RefSeq) heat shock protein 90 alpha family class A member 1
  KO
K04079  molecular chaperone HtpG
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04151  PI3K-Akt signaling pathway
hsa04217  Necroptosis
hsa04612  Antigen processing and presentation
hsa04621  NOD-like receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04659  Th17 cell differentiation
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
hsa05132  Salmonella infection
hsa05200  Pathways in cancer
hsa05207  Chemical carcinogenesis - receptor activation
hsa05215  Prostate cancer
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Alvespimycin hydrochloride: D06554
Ganetespib: D10126
Luminespib (DG01842): D10646 D10647
Onalespib (DG03099): D10719 D11766
Pimitespib: D11920<JP>
Retaspimycin (DG01880): D09375 D09376
Tanespimycin: D06650
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3320 (HSP90AA1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3320 (HSP90AA1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    3320 (HSP90AA1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    3320 (HSP90AA1)
   04612 Antigen processing and presentation
    3320 (HSP90AA1)
   04659 Th17 cell differentiation
    3320 (HSP90AA1)
   04657 IL-17 signaling pathway
    3320 (HSP90AA1)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3320 (HSP90AA1)
   04914 Progesterone-mediated oocyte maturation
    3320 (HSP90AA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3320 (HSP90AA1)
   05207 Chemical carcinogenesis - receptor activation
    3320 (HSP90AA1)
  09162 Cancer: specific types
   05215 Prostate cancer
    3320 (HSP90AA1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    3320 (HSP90AA1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    3320 (HSP90AA1)
   05418 Fluid shear stress and atherosclerosis
    3320 (HSP90AA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3320 (HSP90AA1)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3320 (HSP90AA1)
   04131 Membrane trafficking [BR:hsa04131]
    3320 (HSP90AA1)
   03051 Proteasome [BR:hsa03051]
    3320 (HSP90AA1)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3320 (HSP90AA1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3320 (HSP90AA1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3320 (HSP90AA1)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP90
   3320 (HSP90AA1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3320 (HSP90AA1)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3320 (HSP90AA1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    3320 (HSP90AA1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3320 (HSP90AA1)
SSDB
Motif
Pfam: HSP90 HATPase_c_3 HATPase_c LOH1CR12
Other DBs
NCBI-GeneID: 3320
NCBI-ProteinID: NP_005339
OMIM: 140571
HGNC: 5253
Ensembl: ENSG00000080824
UniProt: P07900 K9JA46
Structure
Position
14:complement(102080742..102139749)
AA seq 732 aa
MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR
YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME
ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM
GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED
KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN
PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN
IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC
LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY
CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT
LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV
TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK
DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE
GDDDTSRMEEVD
NT seq 2199 nt   +upstreamnt  +downstreamnt
atgcctgaggaaacccagacccaagaccaaccgatggaggaggaggaggttgagacgttc
gcctttcaggcagaaattgcccagttgatgtcattgatcatcaatactttctactcgaac
aaagagatctttctgagagagctcatttcaaattcatcagatgcattggacaaaatccgg
tatgaaagcttgacagatcccagtaaattagactctgggaaagagctgcatattaacctt
ataccgaacaaacaagatcgaactctcactattgtggatactggaattggaatgaccaag
gctgacttgatcaataaccttggtactatcgccaagtctgggaccaaagcgttcatggaa
gctttgcaggctggtgcagatatctctatgattggccagttcggtgttggtttttattct
gcttatttggttgctgagaaagtaactgtgatcaccaaacataacgatgatgagcagtac
gcttgggagtcctcagcagggggatcattcacagtgaggacagacacaggtgaacctatg
ggtcgtggaacaaaagttatcctacacctgaaagaagaccaaactgagtacttggaggaa
cgaagaataaaggagattgtgaagaaacattctcagtttattggatatcccattactctt
tttgtggagaaggaacgtgataaagaagtaagcgatgatgaggctgaagaaaaggaagac
aaagaagaagaaaaagaaaaagaagagaaagagtcggaagacaaacctgaaattgaagat
gttggttctgatgaggaagaagaaaagaaggatggtgacaagaagaagaagaagaagatt
aaggaaaagtacatcgatcaagaagagctcaacaaaacaaagcccatctggaccagaaat
cccgacgatattactaatgaggagtacggagaattctataagagcttgaccaatgactgg
gaagatcacttggcagtgaagcatttttcagttgaaggacagttggaattcagagccctt
ctatttgtcccacgacgtgctccttttgatctgtttgaaaacagaaagaaaaagaacaac
atcaaattgtatgtacgcagagttttcatcatggataactgtgaggagctaatccctgaa
tatctgaacttcattagaggggtggtagactcggaggatctccctctaaacatatcccgt
gagatgttgcaacaaagcaaaattttgaaagttatcaggaagaatttggtcaaaaaatgc
ttagaactctttactgaactggcggaagataaagagaactacaagaaattctatgagcag
ttctctaaaaacataaagcttggaatacacgaagactctcaaaatcggaagaagctttca
gagctgttaaggtactacacatctgcctctggtgatgagatggtttctctcaaggactac
tgcaccagaatgaaggagaaccagaaacatatctattatatcacaggtgagaccaaggac
caggtagctaactcagcctttgtggaacgtcttcggaaacatggcttagaagtgatctat
atgattgagcccattgatgagtactgtgtccaacagctgaaggaatttgaggggaagact
ttagtgtcagtcaccaaagaaggcctggaacttccagaggatgaagaagagaaaaagaag
caggaagagaaaaaaacaaagtttgagaacctctgcaaaatcatgaaagacatattggag
aaaaaagttgaaaaggtggttgtgtcaaaccgattggtgacatctccatgctgtattgtc
acaagcacatatggctggacagcaaacatggagagaatcatgaaagctcaagccctaaga
gacaactcaacaatgggttacatggcagcaaagaaacacctggagataaaccctgaccat
tccattattgagaccttaaggcaaaaggcagaggctgataagaacgacaagtctgtgaag
gatctggtcatcttgctttatgaaactgcgctcctgtcttctggcttcagtctggaagat
ccccagacacatgctaacaggatctacaggatgatcaaacttggtctgggtattgatgaa
gatgaccctactgctgatgataccagtgctgctgtaactgaagaaatgccaccccttgaa
ggagatgacgacacatcacgcatggaagaagtagactaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (86)   
   RefGene (43)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (38)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (54)   
   RefSeq(nuc) (4)   
   GenBank (25)   
   EMBL (25)   
3D Structure (344)   
   PDB (344)   
Protein domain (4)   
   Pfam (4)   
All databases (496)   

Download RDF
KEGG   Homo sapiens (human): 3326
Entry
3326              CDS       T01001                                 
Symbol
HSP90AB1, D6S182, HSP84, HSP90B, HSPC2, HSPCB
Name
(RefSeq) heat shock protein 90 alpha family class B member 1
  KO
K04079  molecular chaperone HtpG
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04151  PI3K-Akt signaling pathway
hsa04217  Necroptosis
hsa04612  Antigen processing and presentation
hsa04621  NOD-like receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04659  Th17 cell differentiation
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
hsa05132  Salmonella infection
hsa05200  Pathways in cancer
hsa05207  Chemical carcinogenesis - receptor activation
hsa05215  Prostate cancer
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Alvespimycin hydrochloride: D06554
Ganetespib: D10126
Luminespib (DG01842): D10646 D10647
Onalespib (DG03099): D10719 D11766
Pimitespib: D11920<JP>
Retaspimycin (DG01880): D09375 D09376
Tanespimycin: D06650
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    3326 (HSP90AB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    3326 (HSP90AB1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    3326 (HSP90AB1)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    3326 (HSP90AB1)
   04612 Antigen processing and presentation
    3326 (HSP90AB1)
   04659 Th17 cell differentiation
    3326 (HSP90AB1)
   04657 IL-17 signaling pathway
    3326 (HSP90AB1)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    3326 (HSP90AB1)
   04914 Progesterone-mediated oocyte maturation
    3326 (HSP90AB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3326 (HSP90AB1)
   05207 Chemical carcinogenesis - receptor activation
    3326 (HSP90AB1)
  09162 Cancer: specific types
   05215 Prostate cancer
    3326 (HSP90AB1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    3326 (HSP90AB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    3326 (HSP90AB1)
   05418 Fluid shear stress and atherosclerosis
    3326 (HSP90AB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    3326 (HSP90AB1)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    3326 (HSP90AB1)
   04131 Membrane trafficking [BR:hsa04131]
    3326 (HSP90AB1)
   03051 Proteasome [BR:hsa03051]
    3326 (HSP90AB1)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    3326 (HSP90AB1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3326 (HSP90AB1)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     3326 (HSP90AB1)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP90
   3326 (HSP90AB1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    3326 (HSP90AB1)
Proteasome [BR:hsa03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    3326 (HSP90AB1)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    3326 (HSP90AB1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   3326 (HSP90AB1)
SSDB
Motif
Pfam: HSP90 HATPase_c_3 HATPase_c MIT_ATG1
Other DBs
NCBI-GeneID: 3326
NCBI-ProteinID: NP_001258898
OMIM: 140572
HGNC: 5258
Ensembl: ENSG00000096384
UniProt: P08238
Structure
Position
6:44246194..44253883
AA seq 724 aa
MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLT
DPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAG
ADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTK
VILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEE
DKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEE
YGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRV
FIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELA
EDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQ
KSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEG
LELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTA
NMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFE
TALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRM
EEVD
NT seq 2175 nt   +upstreamnt  +downstreamnt
atgcctgaggaagtgcaccatggagaggaggaggtggagacttttgcctttcaggcagaa
attgcccaactcatgtccctcatcatcaataccttctattccaacaaggagattttcctt
cgggagttgatctctaatgcttctgatgccttggacaagattcgctatgagagcctgaca
gacccttcgaagttggacagtggtaaagagctgaaaattgacatcatccccaaccctcag
gaacgtaccctgactttggtagacacaggcattggcatgaccaaagctgatctcataaat
aatttgggaaccattgccaagtctggtactaaagcattcatggaggctcttcaggctggt
gcagacatctccatgattgggcagtttggtgttggcttttattctgcctacttggtggca
gagaaagtggttgtgatcacaaagcacaacgatgatgaacagtatgcttgggagtcttct
gctggaggttccttcactgtgcgtgctgaccatggtgagcccattggcaggggtaccaaa
gtgatcctccatcttaaagaagatcagacagagtacctagaagagaggcgggtcaaagaa
gtagtgaagaagcattctcagttcataggctatcccatcaccctttatttggagaaggaa
cgagagaaggaaattagtgatgatgaggcagaggaagagaaaggtgagaaagaagaggaa
gataaagatgatgaagaaaaacccaagatcgaagatgtgggttcagatgaggaggatgac
agcggtaaggataagaagaagaaaactaagaagatcaaagagaaatacattgatcaggaa
gaactaaacaagaccaagcctatttggaccagaaaccctgatgacatcacccaagaggag
tatggagaattctacaagagcctcactaatgactgggaagaccacttggcagtcaagcac
ttttctgtagaaggtcagttggaattcagggcattgctatttattcctcgtcgggctccc
tttgacctttttgagaacaagaagaaaaagaacaacatcaaactctatgtccgccgtgtg
ttcatcatggacagctgtgatgagttgataccagagtatctcaattttatccgtggtgtg
gttgactctgaggatctgcccctgaacatctcccgagaaatgctccagcagagcaaaatc
ttgaaagtcattcgcaaaaacattgttaagaagtgccttgagctcttctctgagctggca
gaagacaaggagaattacaagaaattctatgaggcattctctaaaaatctcaagcttgga
atccacgaagactccactaaccgccgccgcctgtctgagctgctgcgctatcatacctcc
cagtctggagatgagatgacatctctgtcagagtatgtttctcgcatgaaggagacacag
aagtccatctattacatcactggtgagagcaaagagcaggtggccaactcagcttttgtg
gagcgagtgcggaaacggggcttcgaggtggtatatatgaccgagcccattgacgagtac
tgtgtgcagcagctcaaggaatttgatgggaagagcctggtctcagttaccaaggagggt
ctggagctgcctgaggatgaggaggagaagaagaagatggaagagagcaaggcaaagttt
gagaacctctgcaagctcatgaaagaaatcttagataagaaggttgagaaggtgacaatc
tccaatagacttgtgtcttcaccttgctgcattgtgaccagcacctacggctggacagcc
aatatggagcggatcatgaaagcccaggcacttcgggacaactccaccatgggctatatg
atggccaaaaagcacctggagatcaaccctgaccaccccattgtggagacgctgcggcag
aaggctgaggccgacaagaatgataaggcagttaaggacctggtggtgctgctgtttgaa
accgccctgctatcttctggcttttcccttgaggatccccagacccactccaaccgcatc
tatcgcatgatcaagctaggtctaggtattgatgaagatgaagtggcagcagaggaaccc
aatgctgcagttcctgatgagatcccccctctcgagggcgatgaggatgcgtctcgcatg
gaagaagtcgattag

  All links  
Disease (1)   
   OMIM (1)   
Gene (85)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (70)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (67)   
   RefSeq(nuc) (7)   
   GenBank (30)   
   EMBL (30)   
3D Structure (29)   
   PDB (29)   
Protein domain (4)   
   Pfam (4)   
All databases (194)   

Download RDF
KEGG   Homo sapiens (human): 7184
Entry
7184              CDS       T01001                                 
Symbol
HSP90B1, ECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1
Name
(RefSeq) heat shock protein 90 beta family member 1
  KO
K09487  heat shock protein 90kDa beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04151  PI3K-Akt signaling pathway
hsa04657  IL-17 signaling pathway
hsa04915  Estrogen signaling pathway
hsa04918  Thyroid hormone synthesis
hsa05132  Salmonella infection
hsa05200  Pathways in cancer
hsa05207  Chemical carcinogenesis - receptor activation
hsa05215  Prostate cancer
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Drug target
Alvespimycin hydrochloride: D06554
Ganetespib: D10126
Luminespib (DG01842): D10646 D10647
Onalespib (DG03099): D10719 D11766
Pimitespib: D11920<JP>
Retaspimycin (DG01880): D09375 D09376
Tanespimycin: D06650
Vitespen: D06667
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    7184 (HSP90B1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    7184 (HSP90B1)
 09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    7184 (HSP90B1)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    7184 (HSP90B1)
   04918 Thyroid hormone synthesis
    7184 (HSP90B1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7184 (HSP90B1)
   05207 Chemical carcinogenesis - receptor activation
    7184 (HSP90B1)
  09162 Cancer: specific types
   05215 Prostate cancer
    7184 (HSP90B1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    7184 (HSP90B1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    7184 (HSP90B1)
   05418 Fluid shear stress and atherosclerosis
    7184 (HSP90B1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    7184 (HSP90B1)
   04131 Membrane trafficking [BR:hsa04131]
    7184 (HSP90B1)
Chaperones and folding catalysts [BR:hsa03110]
 Heat shock proteins
  HSP90
   7184 (HSP90B1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    7184 (HSP90B1)
SSDB
Motif
Pfam: HSP90 HATPase_c_3 HATPase_c PHA01746 DUF4518
Other DBs
NCBI-GeneID: 7184
NCBI-ProteinID: NP_003290
OMIM: 191175
HGNC: 12028
Ensembl: ENSG00000166598
UniProt: P14625 V9HWP2
Structure
Position
12:103930410..103947926
AA seq 803 aa
MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDG
LNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISL
TDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTE
AQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNT
LGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAK
EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYK
SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD
DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKY
NDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYF
MAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDE
SEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMER
IMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFET
ATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDE
EMDVGTDEEEETAKESTAEKDEL
NT seq 2412 nt   +upstreamnt  +downstreamnt
atgagggccctgtgggtgctgggcctctgctgcgtcctgctgaccttcgggtcggtcaga
gctgacgatgaagttgatgtggatggtacagtagaagaggatctgggtaaaagtagagaa
ggatcaaggacggatgatgaagtagtacagagagaggaagaagctattcagttggatgga
ttaaatgcatcacaaataagagaacttagagagaagtcggaaaagtttgccttccaagcc
gaagttaacagaatgatgaaacttatcatcaattcattgtataaaaataaagagattttc
ctgagagaactgatttcaaatgcttctgatgctttagataagataaggctaatatcactg
actgatgaaaatgctctttctggaaatgaggaactaacagtcaaaattaagtgtgataag
gagaagaacctgctgcatgtcacagacaccggtgtaggaatgaccagagaagagttggtt
aaaaaccttggtaccatagccaaatctgggacaagcgagtttttaaacaaaatgactgaa
gcacaggaagatggccagtcaacttctgaattgattggccagtttggtgtcggtttctat
tccgccttccttgtagcagataaggttattgtcacttcaaaacacaacaacgatacccag
cacatctgggagtctgactccaatgaattttctgtaattgctgacccaagaggaaacact
ctaggacggggaacgacaattacccttgtcttaaaagaagaagcatctgattaccttgaa
ttggatacaattaaaaatctcgtcaaaaaatattcacagttcataaactttcctatttat
gtatggagcagcaagactgaaactgttgaggagcccatggaggaagaagaagcagccaaa
gaagagaaagaagaatctgatgatgaagctgcagtagaggaagaagaagaagaaaagaaa
ccaaagactaaaaaagttgaaaaaactgtctgggactgggaacttatgaatgatatcaaa
ccaatatggcagagaccatcaaaagaagtagaagaagatgaatacaaagctttctacaaa
tcattttcaaaggaaagtgatgaccccatggcttatattcactttactgctgaaggggaa
gttaccttcaaatcaattttatttgtacccacatctgctccacgtggtctgtttgacgaa
tatggatctaaaaagagcgattacattaagctctatgtgcgccgtgtattcatcacagac
gacttccatgatatgatgcctaaatacctcaattttgtcaagggtgtggtggactcagat
gatctccccttgaatgtttcccgcgagactcttcagcaacataaactgcttaaggtgatt
aggaagaagcttgttcgtaaaacgctggacatgatcaagaagattgctgatgataaatac
aatgatactttttggaaagaatttggtaccaacatcaagcttggtgtgattgaagaccac
tcgaatcgaacacgtcttgctaaacttcttaggttccagtcttctcatcatccaactgac
attactagcctagaccagtatgtggaaagaatgaaggaaaaacaagacaaaatctacttc
atggctgggtccagcagaaaagaggctgaatcttctccatttgttgagcgacttctgaaa
aagggctatgaagttatttacctcacagaacctgtggatgaatactgtattcaggccctt
cccgaatttgatgggaagaggttccagaatgttgccaaggaaggagtgaagttcgatgaa
agtgagaaaactaaggagagtcgtgaagcagttgagaaagaatttgagcctctgctgaat
tggatgaaagataaagcccttaaggacaagattgaaaaggctgtggtgtctcagcgcctg
acagaatctccgtgtgctttggtggccagccagtacggatggtctggcaacatggagaga
atcatgaaagcacaagcgtaccaaacgggcaaggacatctctacaaattactatgcgagt
cagaagaaaacatttgaaattaatcccagacacccgctgatcagagacatgcttcgacga
attaaggaagatgaagatgataaaacagttttggatcttgctgtggttttgtttgaaaca
gcaacgcttcggtcagggtatcttttaccagacactaaagcatatggagatagaatagaa
agaatgcttcgcctcagtttgaacattgaccctgatgcaaaggtggaagaagagcccgaa
gaagaacctgaagagacagcagaagacacaacagaagacacagagcaagacgaagatgaa
gaaatggatgtgggaacagatgaagaagaagaaacagcaaaggaatctacagctgaaaaa
gatgaattgtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (44)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (29)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (35)   
   RefSeq(nuc) (1)   
   GenBank (17)   
   EMBL (17)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (91)   

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