KEGG T01001: 3352

Homo sapiens (human): 3352

Entry

3352              CDS       T01001

Symbol

HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4

Name

(RefSeq) 5-hydroxytryptamine receptor 1D

K04153

5-hydroxytryptamine receptor 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04024

cAMP signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04082

Neuroactive ligand signaling

hsa04726

Serotonergic synapse

hsa04742

Taste transduction

Network

nt06544 Neuroactive ligand signaling

Element

N01901

Serotonin-HTR1/5-GNAI/O signaling pathway

Drug target

Almotriptan (DG00839):

D02824 D02825<US>

Alniditan dihydrochloride:

D02826

Avitriptan fumarate:

D03014

Cinitapride (DG01520):

D07700 D07701

Cyproheptadine (DG01109):

D02234<JP/US> D07765

Dihydroergotamine (DG00833):

D02211<US> D07837 D07838

Eletriptan (DG00840):

D01973<JP/US> D07887 D11617

Elzasonan (DG01314):

D03982 D03983

Ergot alkaloids:

D07906

Ergotamine (DG00834):

D00679<US>

Fenfluramine (DG00103):

D04148<JP/US> D07945

Frovatriptan (DG00841):

D04264<US> D07997

Indorenate hydrochloride:

D04533

Naratriptan (DG00837):

D00674<JP/US> D08255

Pizotifen (DG00842):

D05523 D08397

Rizatriptan (DG00838):

D00675<JP/US> D05740 D08485

Sumatriptan (DG00836):

D00451<JP/US> D00676<JP/US>

Zolmitriptan:

D00415<JP/US>

Zotepine:

D01321<JP>

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3352 (HTR1D)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3352 (HTR1D)
   04082 Neuroactive ligand signaling
    3352 (HTR1D)
09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3352 (HTR1D)
  09157 Sensory system
   04742 Taste transduction
    3352 (HTR1D)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    3352 (HTR1D)
G protein-coupled receptors [BR:hsa04030]
Rhodopsin family
  Biogenic amine
   Serotonin
    3352 (HTR1D)

SSDB

Motif

Pfam:

7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

Position

1:complement(23191895..23217502)

AA seq 377 aa
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS

NT seq 1134 nt +upstreamnt +downstreamnt
atgtccccactgaaccagtcagcagaaggccttccccaggaggcctccaacagatccctg
aatgccacagaaacctcagaggcttgggatcccaggaccctccaggcgctcaagatctcc
cttgccgtggtcctttccgtcatcacactggccacagtcctctccaatgcctttgtactc
accaccatcttactcaccaggaagctccacacccctgccaactacctgattggctccctg
gccaccaccgacctcttggtttccatcttggtaatgcccatcagcatcgcctataccatc
acccacacctggaactttggccaaatcttgtgtgacatctggctgtcctctgacatcacg
tgctgcacagcctccatcctgcatctctgtgtcattgctctggacaggtactgggcaatc
acagatgccctggaatacagtaaacgcaggacggctggccacgcggccaccatgatcgcc
attgtctgggccatctccatctgcatctccatccccccgctcttctggcggcaggccaag
gcccaggaggagatgtcggactgtctggtgaacacctctcagatctcctacaccatctac
tccacctgtggggccttctacattccctcggtgttgctcatcatcctatatggccggatc
taccgggctgcccggaaccgcatcctgaatccaccctcactctatgggaagcgcttcacc
acggcccacctcatcacaggctctgccgggtcctcgctctgctcgctcaactccagcctc
catgaggggcactcgcactcggctggctcccctctctttttcaaccacgtgaaaatcaag
cttgctgacagtgccctggaacgcaagaggatttctgctgctcgagaaaggaaagccact
aaaatcctgggcatcattctgggggcctttatcatctgctggctgcccttcttcgtggtg
tctctggtcctccccatctgccgggactcctgctggatccacccggcgctctttgacttc
ttcacctggctaggctatttaaactccctcatcaatccaataatctacactgtgtttaat
gaagagtttcggcaagcttttcagaaaattgtccctttccggaaggcctcctag

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