KEGG   Homo sapiens (human): 3359
Entry
3359              CDS       T01001                                 
Symbol
HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Name
(RefSeq) 5-hydroxytryptamine receptor 3A
  KO
K04819  5-hydroxytryptamine receptor 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04082  Neuroactive ligand signaling
hsa04726  Serotonergic synapse
hsa04742  Taste transduction
Drug target
Alosetron (DG00046): D02829<US> D07129
Azasetron (DG01521): D01613 D07481
Batanopride hydrochloride: D03060
Bemesetron: D03073
Cilansetron (DG00047): D03495 D03496
Cisapride (DG00056): D00274 D02092
Clozapine: D00283<JP/US>
Dazopride fumarate: D03662
Dolasetron (DG00063): D00725 D07867
Fabesetron hydrochloride: D01838
Galdansetron hydrochloride: D04294
Indisetron hydrochloride: D02632
Itasetron (DG01240): D04642 D09749
Lurosetron mesylate: D04821
Mianserin (DG00951): D01358<JP> D08216
Mirisetron maleate: D05050
Mirtazapine (DG02838): D00563<JP/US> D11056
Ondansetron (DG00060): D00456<US> D00678<JP/US>
Palonosetron (DG00064): D05343<JP/US> D07175
Pancopride: D05348
Quipazine maleate: D05685
Ramosetron (DG01239): D02016<JP> D08466
Renzapride: D06396
Tedatioxetine (DG01311): D10170 D10171
Tropanserin hydrochloride: D06253
Tropisetron (DG00062): D02041 D02130
Vortioxetine (DG00965): D10184 D10185<JP/US> D12544
Zacopride hydrochloride: D06353
Zatosetron maleate: D06358
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    3359 (HTR3A)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    3359 (HTR3A)
  09157 Sensory system
   04742 Taste transduction
    3359 (HTR3A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3359 (HTR3A)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  Serotonin (5-HT3)
   3359 (HTR3A)
SSDB
Motif
Pfam: Neur_chan_LBD Neur_chan_memb
Other DBs
NCBI-GeneID: 3359
NCBI-ProteinID: NP_000860
OMIM: 182139
HGNC: 5297
Ensembl: ENSG00000166736
UniProt: P46098 B4E398
Structure
Position
11:113975108..113990313
AA seq 478 aa
MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTT
VSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDI
LINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLH
TIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRR
RPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAI
GTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQ
STSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQ
ELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA
NT seq 1437 nt   +upstreamnt  +downstreamnt
atgctgctgtgggtccagcaggcgctgctcgccttgctcctccccacactcctggcacag
ggagaagccaggaggagccgaaacaccaccaggcccgctctgctgaggctgtcggattac
cttttgaccaactacaggaagggtgtgcgccccgtgagggactggaggaagccaaccacc
gtatccattgacgtcattgtctatgccatcctcaacgtggatgagaagaatcaggtgctg
accacctacatctggtaccggcagtactggactgatgagtttctccagtggaaccctgag
gactttgacaacatcaccaagttgtccatccccacggacagcatctgggtcccggacatt
ctcatcaatgagttcgtggatgtggggaagtctccaaatatcccgtacgtgtatattcgg
catcaaggcgaagttcagaactacaagccccttcaggtggtgactgcctgtagcctcgac
atctacaacttccccttcgatgtccagaactgctcgctgaccttcaccagttggctgcac
accatccaggacatcaacatctctttgtggcgcttgccagaaaaggtgaaatccgacagg
agtgtcttcatgaaccagggagagtgggagttgctgggggtgctgccctactttcgggag
ttcagcatggaaagcagtaactactatgcagaaatgaagttctatgtggtcatccgccgg
cggcccctcttctatgtggtcagcctgctactgcccagcatcttcctcatggtcatggac
atcgtgggcttctacctgccccccaacagtggcgagagggtctctttcaagattacactc
ctcctgggctactcggtcttcctgatcatcgtttctgacacgctgccggccactgccatc
ggcactcctctcattggtgtctactttgtggtgtgcatggctctgctggtgataagtttg
gccgagaccatcttcattgtgcggctggtgcacaagcaagacctgcagcagcccgtgcct
gcttggctgcgtcacctggttctggagagaatcgcctggctactttgcctgagggagcag
tcaacttcccagaggcccccagccacctcccaagccaccaagactgatgactgctcagcc
atgggaaaccactgcagccacatgggaggaccccaggacttcgagaagagcccgagggac
agatgtagccctcccccaccacctcgggaggcctcgctggcggtgtgtgggctgctgcag
gagctgtcctccatccggcaattcctggaaaagcgggatgagatccgagaggtggcccga
gactggctgcgcgtgggctccgtgctggacaagctgctattccacatttacctgctagcg
gtgctggcctacagcatcaccctggttatgctctggtccatctggcagtacgcttga

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (66)   

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