KEGG   Homo sapiens (human): 3375
Entry
3375              CDS       T01001                                 
Symbol
IAPP, DAP, IAP
Name
(RefSeq) islet amyloid polypeptide
  KO
K08039  islet amyloid polypeptide
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04081  Hormone signaling
hsa04950  Maturity onset diabetes of the young
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3375 (IAPP)
   04081 Hormone signaling
    3375 (IAPP)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04950 Maturity onset diabetes of the young
    3375 (IAPP)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    3375 (IAPP)
Cytokines and neuropeptides [BR:hsa04052]
 Neuropeptides
  GPCR binding
   3375 (IAPP)
SSDB
Motif
Pfam: Calc_CGRP_IAPP
Other DBs
NCBI-GeneID: 3375
NCBI-ProteinID: NP_000406
OMIM: 147940
HGNC: 5329
Ensembl: ENSG00000121351
CPD: C16130
UniProt: P10997
Structure
Position
12:21354959..21379980
AA seq 89 aa
MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAIL
SSTNVGSNTYGKRNAVEVLKREPLNYLPL
NT seq 270 nt   +upstreamnt  +downstreamnt
atgggcatcctgaagctgcaagtatttctcattgtgctctctgttgcattgaaccatctg
aaagctacacccattgaaagtcatcaggtggaaaagcggaaatgcaacactgccacatgt
gcaacgcagcgcctggcaaattttttagttcattccagcaacaactttggtgccattctc
tcatctaccaacgtgggatccaatacatatggcaagaggaatgcagtagaggttttaaag
agagagccactgaattacttgcccctttag

  All links  
Disease (1)   
   OMIM (1)   
Gene (6)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
3D Structure (56)   
   PDB (56)   
Protein domain (1)   
   Pfam (1)   
All databases (86)   

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