KEGG   Homo sapiens (human): 345456
Entry
345456            CDS       T01001                                 
Symbol
PFN3, profilin-3
Name
(RefSeq) profilin 3
  KO
K05759  profilin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04810  Regulation of actin cytoskeleton
hsa05014  Amyotrophic lateral sclerosis
hsa05131  Shigellosis
hsa05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    345456 (PFN3)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    345456 (PFN3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    345456 (PFN3)
   05131 Shigellosis
    345456 (PFN3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    345456 (PFN3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    345456 (PFN3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    345456 (PFN3)
   04147 Exosome [BR:hsa04147]
    345456 (PFN3)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Others
    345456 (PFN3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Profilin
     345456 (PFN3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   345456 (PFN3)
SSDB
Motif
Pfam: Profilin FMN_dh
Other DBs
NCBI-GeneID: 345456
NCBI-ProteinID: NP_001025057
OMIM: 612812
HGNC: 18627
Ensembl: ENSG00000196570
UniProt: P60673
Position
5:complement(177400109..177400661)
AA seq 137 aa
MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL
QAGLSVGGRRCCVIRDHLLAEGDGVLDARTKGLDARAVCVGRAPRALLVLMGRRGVHGGI
LNKTVHELIRGLRMQGA
NT seq 414 nt   +upstreamnt  +downstreamnt
atgggcgactggaaggtctacatcagtgcagtgctgcgggaccagcgcatcgacgacgtg
gccatcgtgggccatgcggacaacagctgcgtgtgggcttcgcggcccgggggcctgctg
gcggccatctcgccgcaggaggtgggcgtgctcacggggccggacaggcacaccttcctg
caggcgggcctgagcgtggggggccgccgctgctgcgtcatccgcgaccacctgctggcc
gagggtgacggcgtgctggacgcacgcaccaaggggctggacgcgcgcgccgtgtgcgtg
ggccgtgcgccgcgcgcgctcctggtgctaatgggccgacgcggcgtacatgggggcatc
ctcaacaagacggtgcacgaactcatacgcgggctgcgcatgcagggcgcctag

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