KEGG   Homo sapiens (human): 345611
Entry
345611            CDS       T01001                                 
Symbol
IRGM, IBD19, IFI1, IRGM1, LRG-47, LRG47
Name
(RefSeq) immunity related GTPase M
  KO
K14139  immunity-related GTPase family M protein [EC:3.6.5.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05145  Toxoplasmosis
Network
nt06521  NLR signaling
  Element
N01568  Regulation of NLRP3 inflammasome signaling pathway, NLRP3 inhibition
Disease
H00286  Crohn disease
H00342  Tuberculosis
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    345611 (IRGM)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    345611 (IRGM)
SSDB
Motif
Pfam: IIGP LYTB Sigma54_activ_2 RsgA_GTPase SRP54 Dynamin_N
Other DBs
NCBI-GeneID: 345611
NCBI-ProteinID: NP_001139277
OMIM: 608212
HGNC: 29597
Ensembl: ENSG00000237693
UniProt: A1A4Y4
Position
5:150846521..150902402
AA seq 181 aa
MEAMNVEKASADGNLPEVISNIKETLKIVSRTPVNITMAGDSGNGMSTFISALRNTGHEG
KASPPTELVKATQRCASYFSSHFSNVVLWDLPGTGSATTTLENYLMEMQFNRYDFIMVAS
AQFSMNHVMLAKTAEDMGKKFYIVWTKLDMDLSTGALPEVQLLQIRENVLENLQKERVCE
Y
NT seq 546 nt   +upstreamnt  +downstreamnt
atggaagccatgaatgttgagaaagcctcagcagatgggaacttgccagaggtgatctct
aacatcaaggagactctgaagatagtgtccaggacaccagttaacatcactatggcaggg
gactctggcaatgggatgtccaccttcatcagtgcccttcgaaacacaggacatgagggt
aaggcctcacctcctactgagctggtaaaagctacccaaagatgtgcctcctatttctct
tcccacttttcaaatgtggtgttgtgggacctgcctggcacagggtctgccaccacaacc
ctggagaactacctgatggaaatgcagttcaaccggtatgacttcatcatggttgcatct
gcacaattcagcatgaatcatgtgatgcttgccaaaaccgctgaggacatgggaaagaag
ttctacattgtctggaccaagctagacatggacctcagcacaggtgccctcccagaagtg
cagctactgcagatcagagaaaatgtcctggaaaatctccagaaggagcgggtatgtgaa
tactaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (11)   
   RefSeq(nuc) (3)   
   GenBank (4)   
   EMBL (4)   
Protein domain (6)   
   Pfam (6)   
All databases (30)   

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