KEGG   Homo sapiens (human): 348Help
Entry
348               CDS       T01001                                 

Gene name
APOE, AD2, APO-E, ApoE4, LDLCQ5, LPG
Definition
(RefSeq) apolipoprotein E
  KO
K04524  apolipoprotein E
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
hsa05010  Alzheimer disease
Disease
H00056  Alzheimer disease
H00156  Hyperlipoproteinemia, type III
H00887  Lipoprotein glomerulopathy
H01168  Sea-blue histiocyte disease
H01637  Hypertriglyceridemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    348 (APOE)
 09160 Human Diseases
  09164 Neurodegenerative diseases
   05010 Alzheimer disease
    348 (APOE)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    348 (APOE)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    348 (APOE)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   348 (APOE)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Others
   348 (APOE)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Apolipoprotein ApoLp-III Phage_Mu_Gam DUF883 CHASE6_C DIT1_PvcA YtxH LEDGF Prominin Apo-CIII MSP1_C Phasin OmpH TetR_C_24 RE_HindIII CdvA
Motif
Other DBs
NCBI-GeneID: 348
NCBI-ProteinID: NP_000032
OMIM: 107741
HGNC: 613
Ensembl: ENSG00000130203
Vega: OTTHUMG00000128901
Pharos: P02649(Tbio)
UniProt: P02649 A0A0S2Z3D5
Structure
PDB: 

Position
19q13.32
AA seq 317 aa AA seqDB search
MKVLWAALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQT
LSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQA
RLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY
QAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMG
SRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEK
VQAAVGTSAAPVPSDNH
NT seq 954 nt NT seq  +upstreamnt  +downstreamnt
atgaaggttctgtgggctgcgttgctggtcacattcctggcaggatgccaggccaaggtg
gagcaagcggtggagacagagccggagcccgagctgcgccagcagaccgagtggcagagc
ggccagcgctgggaactggcactgggtcgcttttgggattacctgcgctgggtgcagaca
ctgtctgagcaggtgcaggaggagctgctcagctcccaggtcacccaggaactgagggcg
ctgatggacgagaccatgaaggagttgaaggcctacaaatcggaactggaggaacaactg
accccggtggcggaggagacgcgggcacggctgtccaaggagctgcaggcggcgcaggcc
cggctgggcgcggacatggaggacgtgtgcggccgcctggtgcagtaccgcggcgaggtg
caggccatgctcggccagagcaccgaggagctgcgggtgcgcctcgcctcccacctgcgc
aagctgcgtaagcggctcctccgcgatgccgatgacctgcagaagcgcctggcagtgtac
caggccggggcccgcgagggcgccgagcgcggcctcagcgccatccgcgagcgcctgggg
cccctggtggaacagggccgcgtgcgggccgccactgtgggctccctggccggccagccg
ctacaggagcgggcccaggcctggggcgagcggctgcgcgcgcggatggaggagatgggc
agccggacccgcgaccgcctggacgaggtgaaggagcaggtggcggaggtgcgcgccaag
ctggaggagcaggcccagcagatacgcctgcaggccgaggccttccaggcccgcctcaag
agctggttcgagcccctggtggaagacatgcagcgccagtgggccgggctggtggagaag
gtgcaggctgccgtgggcaccagcgccgcccctgtgcccagcgacaatcactga

DBGET integrated database retrieval system