KEGG   Homo sapiens (human): 3565Help
Entry
3565              CDS       T01001                                 

Gene name
IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4
Definition
(RefSeq) interleukin 4
  KO
K05430  interleukin 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  Jak-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
hsa04657  IL-17 signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04672  Intestinal immune network for IgA production
hsa05140  Leishmaniasis
hsa05162  Measles
hsa05200  Pathways in cancer
hsa05310  Asthma
hsa05320  Autoimmune thyroid disease
hsa05321  Inflammatory bowel disease (IBD)
hsa05330  Allograft rejection
Network
N00053  Cytokine-Jak-STAT signaling pathway
Disease
H00079  Asthma
Drug target
Pascolizumab: D05377
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    3565 (IL4)
   04151 PI3K-Akt signaling pathway
    3565 (IL4)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3565 (IL4)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    3565 (IL4)
   04660 T cell receptor signaling pathway
    3565 (IL4)
   04658 Th1 and Th2 cell differentiation
    3565 (IL4)
   04659 Th17 cell differentiation
    3565 (IL4)
   04657 IL-17 signaling pathway
    3565 (IL4)
   04664 Fc epsilon RI signaling pathway
    3565 (IL4)
   04672 Intestinal immune network for IgA production
    3565 (IL4)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    3565 (IL4)
  09163 Immune diseases
   05310 Asthma
    3565 (IL4)
   05320 Autoimmune thyroid disease
    3565 (IL4)
   05321 Inflammatory bowel disease (IBD)
    3565 (IL4)
   05330 Allograft rejection
    3565 (IL4)
  09172 Infectious diseases: Viral
   05162 Measles
    3565 (IL4)
  09174 Infectious diseases: Parasitic
   05140 Leishmaniasis
    3565 (IL4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors [BR:hsa04052]
    3565 (IL4)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    3565 (IL4)
Cytokines and growth factors [BR:hsa04052]
 Cytokines
  Interleukins
   3565 (IL4)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate/Haparin
  Cytokines
   3565 (IL4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: IL4 Mannosyl_trans3
Motif
Other DBs
NCBI-GeneID: 3565
NCBI-ProteinID: NP_000580
OMIM: 147780
HGNC: 6014
Ensembl: ENSG00000113520
Vega: OTTHUMG00000059724
Pharos: P05112(Tbio)
UniProt: P05112 D4HNR6
Structure
PDB: 

Position
5q31.1
AA seq 153 aa AA seqDB search
MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAAS
KNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGL
NSCPVKEANQSTLENFLERLKTIMREKYSKCSS
NT seq 462 nt NT seq  +upstreamnt  +downstreamnt
atgggtctcacctcccaactgcttccccctctgttcttcctgctagcatgtgccggcaac
tttgtccacggacacaagtgcgatatcaccttacaggagatcatcaaaactttgaacagc
ctcacagagcagaagactctgtgcaccgagttgaccgtaacagacatctttgctgcctcc
aagaacacaactgagaaggaaaccttctgcagggctgcgactgtgctccggcagttctac
agccaccatgagaaggacactcgctgcctgggtgcgactgcacagcagttccacaggcac
aagcagctgatccgattcctgaaacggctcgacaggaacctctggggcctggcgggcttg
aattcctgtcctgtgaaggaagccaaccagagtacgttggaaaacttcttggaaaggcta
aagacgatcatgagagagaaatattcaaagtgttcgagctga

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