KEGG   Homo sapiens (human): 3587
Entry
3587              CDS       T01001                                 
Symbol
IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
Name
(RefSeq) interleukin 10 receptor subunit alpha
  KO
K05134  interleukin 10 receptor alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04061  Viral protein interaction with cytokine and cytokine receptor
hsa04630  JAK-STAT signaling pathway
hsa05145  Toxoplasmosis
hsa05152  Tuberculosis
hsa05163  Human cytomegalovirus infection
Network
nt06150  Cytokine-cytokine receptor interaction (viruses)
nt06167  Human cytomegalovirus (HCMV)
nt06518  JAK-STAT signaling
  Element
N00415  IL10 family to Jak-STAT signaling pathway
N00416  HCMV vIL10 to IL10-JAK-STAT signaling pathway
N01265  EBV vIL10 to IL10R signaling
Disease
H00286  Crohn disease
H01227  Inflammatory bowel disease (IBD)
Drug target
Ilodecakin: D04505
Pegilodecakin: D11200
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    3587 (IL10RA)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    3587 (IL10RA)
   04061 Viral protein interaction with cytokine and cytokine receptor
    3587 (IL10RA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    3587 (IL10RA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    3587 (IL10RA)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    3587 (IL10RA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:hsa04050]
    3587 (IL10RA)
   04090 CD molecules [BR:hsa04090]
    3587 (IL10RA)
Cytokine receptors [BR:hsa04050]
 Interleukin receptor families
  IL10/28 receptor family
   3587 (IL10RA)
CD molecules [BR:hsa04090]
 Proteins
  3587 (IL10RA)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind
Other DBs
NCBI-GeneID: 3587
NCBI-ProteinID: NP_001549
OMIM: 146933
HGNC: 5964
Ensembl: ENSG00000110324
Pharos: Q13651(Tbio)
UniProt: Q13651
Structure
Position
11:117986394..118003037
AA seq 578 aa
MLPCLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTPIPNQSESTCYEVA
LLRYGIESWNSISNCSQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTNTRFSV
DEVTLTVGSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGNFTF
THKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISLTRQYFTVTNVIIFF
AFVLLLSGALAYCLALQLYVRRRKKLPSVLLFKKPSPFIFISQRPSPETQDTIHPLDEEA
FLKVSPELKNLDLHGSTDSGFGSTKPSLQTEEPQFLLPDPHPQADRTLGNREPPVLGDSC
SSGSSNSTDSGICLQEPSLSPSTGPTWEQQVGSNSRGQDDSGIDLVQNSEGRAGDTQGGS
ALGHHSPPEPEVPGEEDPAAVAFQGYLRQTRCAEEKATKTGCLEEESPLTDGLGPKFGRC
LVDEAGLHPPALAKGYLKQDPLEMTLASSGAPTGQWNQPTEEWSLLALSSCSDLGISDWS
FAHDLAPLGCVAAPGGLLGSFNSDLVTLPLISSLQSSE
NT seq 1737 nt   +upstreamnt  +downstreamnt
atgctgccgtgcctcgtagtgctgctggcggcgctcctcagcctccgtcttggctcagac
gctcatgggacagagctgcccagccctccgtctgtgtggtttgaagcagaatttttccac
cacatcctccactggacacccatcccaaatcagtctgaaagtacctgctatgaagtggcg
ctcctgaggtatggaatagagtcctggaactccatctccaactgtagccagaccctgtcc
tatgaccttaccgcagtgaccttggacctgtaccacagcaatggctaccgggccagagtg
cgggctgtggacggcagccggcactccaactggaccgtcaccaacacccgcttctctgtg
gatgaagtgactctgacagttggcagtgtgaacctagagatccacaatggcttcatcctc
gggaagattcagctacccaggcccaagatggcccccgcaaatgacacatatgaaagcatc
ttcagtcacttccgagagtatgagattgccattcgcaaggtgccgggaaacttcacgttc
acacacaagaaagtaaaacatgaaaacttcagcctcctaacctctggagaagtgggagag
ttctgtgtccaggtgaaaccatctgtcgcttcccgaagtaacaaggggatgtggtctaaa
gaggagtgcatctccctcaccaggcagtatttcaccgtgaccaacgtcatcatcttcttt
gcctttgtcctgctgctctccggagccctcgcctactgcctggccctccagctgtatgtg
cggcgccgaaagaagctacccagtgtcctgctcttcaagaagcccagccccttcatcttc
atcagccagcgtccctccccagagacccaagacaccatccacccgcttgatgaggaggcc
tttttgaaggtgtccccagagctgaagaacttggacctgcacggcagcacagacagtggc
tttggcagcaccaagccatccctgcagactgaagagccccagttcctcctccctgaccct
cacccccaggctgacagaacgctgggaaacagggagccccctgtgctgggggacagctgc
agtagtggcagcagcaatagcacagacagcgggatctgcctgcaggagcccagcctgagc
cccagcacagggcccacctgggagcaacaggtggggagcaacagcaggggccaggatgac
agtggcattgacttagttcaaaactctgagggccgggctggggacacacagggtggctcg
gccttgggccaccacagtcccccggagcctgaggtgcctggggaagaagacccagctgct
gtggcattccagggttacctgaggcagaccagatgtgctgaagagaaggcaaccaagaca
ggctgcctggaggaagaatcgcccttgacagatggccttggccccaaattcgggagatgc
ctggttgatgaggcaggcttgcatccaccagccctggccaagggctatttgaaacaggat
cctctagaaatgactctggcttcctcaggggccccaacgggacagtggaaccagcccact
gaggaatggtcactcctggccttgagcagctgcagtgacctgggaatatctgactggagc
tttgcccatgaccttgcccctctaggctgtgtggcagccccaggtggtctcctgggcagc
tttaactcagacctggtcaccctgcccctcatctctagcctgcagtcaagtgagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (3)   
   KEGG NETWORK (3)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
3D Structure (7)   
   PDB (7)   
Protein domain (2)   
   Pfam (2)   
All databases (84)   

Download RDF
DBGET integrated database retrieval system