KEGG   Homo sapiens (human): 3756
Entry
3756              CDS       T01001                                 
Symbol
KCNH1, EAG, EAG1, K(V)10.1, Kv10.1, TMBTS, ZLS1, h-eag, hEAG, hEAG1
Name
(RefSeq) potassium voltage-gated channel subfamily H member 1
  KO
K04904  potassium voltage-gated channel Eag-related subfamily H member 1
Organism
hsa  Homo sapiens (human)
Disease
H01573  Zimmermann-Laband syndrome
Drug target
Clofilium phosphate: D03547
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    3756 (KCNH1)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   3756 (KCNH1)
SSDB
Motif
Pfam: Ion_trans PAS_9 cNMP_binding Ion_trans_2 PAS PAS_3 PAS_4 Cupin_2 Cupin_3
Other DBs
NCBI-GeneID: 3756
NCBI-ProteinID: NP_758872
OMIM: 603305
HGNC: 6250
Ensembl: ENSG00000143473
UniProt: O95259
Structure
Position
1:complement(210678314..211134148)
AA seq 989 aa
MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEV
MQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQ
DKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHK
HSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVS
FKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDL
LSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLR
LGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLY
QLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFA
VAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYI
VSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTV
HCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCAN
VRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEER
MKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNVLTEHASANH
SLVKASVVTVRESPATPVSFQAASTSGVPDHAKLQAPGSECLGPKGGGGDCAKRKSWARF
KDACGKSEDWNKVSKAESMETLPERTKASGEATLKKTDSCDSGITKSDLRLDNVGEARSP
QDRSPILAEVKHSFYPIPEQTLQATVLEVRHELKEDIKALNAKMTNIEKQLSEILRILTS
RRSSQSPQELFEISRPQSPESERDIFGAS
NT seq 2970 nt   +upstreamnt  +downstreamnt
atgaccatggctgggggcaggaggggactagtggcccctcaaaacacgtttctggagaat
attgttcggcggtccaatgatactaattttgtgttggggaatgctcagatagtggactgg
cctattgtgtacagcaatgatggattttgcaagctgtctggctatcacagggcagaagtg
atgcaaaaaagcagcacctgcagttttatgtatggggagctgactgataaagacacgatt
gaaaaagtgcggcaaacatttgagaactatgagatgaattcctttgaaattctgatgtac
aagaagaacaggacacctgtgtggttctttgtgaaaattgctccaattcgaaacgaacag
gataaagtggttttatttctttgcactttcagtgacataacagctttcaaacagccaatt
gaggatgattcatgtaaaggctgggggaagtttgctcggctgacaagagcactgacaagc
agcaggggtgtcctgcagcagctggctccaagcgtgcaaaaaggcgagaatgtccacaag
cactcccgcctggcagaggtcctacagctgggctcagacatccttccccagtacaagcaa
gaggcaccaaagactccccctcacatcatcttacattattgtgtttttaagaccacgtgg
gattggatcatcttgatcttgaccttctatacagccatcttggtcccttataatgtctcc
ttcaaaaccaggcagaataatgtggcctggctggttgttgatagcatcgtggatgttatc
tttttggtggacattgtgctcaattttcataccacctttgttggaccagcaggggaggtg
atttctgaccccaaacttatccgcatgaactacctgaagacgtggtttgtgattgacctt
ctgtcctgtttgccatatgatgtcatcaacgcttttgagaacgtggatgaggttagtgcc
tttatgggtgatccagggaagattggttttgctgatcagattccaccaccactggagggg
agagagagtcagggcatcagcagcctgttcagctctctaaaagttgtccggctgctccgt
cttgggcgagtggcccgtaagctggaccactacattgaatatggagctgctgtgctggtc
ctgctggtgtgtgtgtttgggctggctgcacactggatggcctgcatctggtacagcatt
ggggactatgagatctttgacgaggacaccaagacaatccgcaacaacagctggctgtac
caactagcgatggacattggcaccccttaccagtttaatgggtctggctcagggaagtgg
gaaggtggtcccagcaagaattctgtctacatctcctcgttgtatttcacaatgaccagc
ctcaccagtgtgggctttgggaacatcgccccatccacagacattgagaagatctttgca
gtggccatcatgatgattggctcacttctctatgccaccatcttcgggaatgtgacgact
attttccaacagatgtatgccaacaccaacagataccatgagatgctcaacagtgttcgg
gacttcctgaagctctaccaggtgccaaaaggattgagtgagcgagtaatggattatatt
gtgtccacttggtccatgtccagaggcattgacacagagaaggtcctgcagatctgcccc
aaggacatgagagccgacatctgcgtgcacctgaaccgcaaggtgttcaaggagcacccg
gccttccggctggccagtgatggctgcctccgggcactggccatggagttccagacggtg
cactgtgccccaggggacctcatctaccatgcaggagagagcgttgacagcctctgcttt
gtggtttctggctccctggaggtgatccaagatgatgaggtggtggccattctaggaaaa
ggagacgtgtttggagatgtgttctggaaggaagccacccttgcccagtcctgtgccaat
gttagggccttgacctactgtgatctgcatgtgatcaagcgggatgccctgcagaaagtg
ctggaattctacacggccttctcccattccttctcccggaacctgattctgacgtacaac
ttgaggaagaggattgtgttccggaagatcagcgatgtgaaacgtgaagaggaagaacgc
atgaaacgaaagaatgaggcccccctgatcttgcccccggaccaccctgtccggcgcctc
ttccagagattccgacagcagaaagaggccaggctggcagctgagagagggggccgggac
ctggatgacctagatgtggagaagggcaatgtccttacagagcatgcctccgccaaccac
agcctcgtgaaggccagcgtggtcaccgtgcgtgagagtcctgccacgcccgtatccttc
caggcagcctccacctccggggtgccagaccacgcaaagctacaggcgccagggtccgag
tgcctgggccccaaggggggcgggggcgattgtgccaagcgcaaaagctgggcccgcttc
aaagatgcttgcgggaagagtgaggactggaacaaggtgtccaaggctgagtcgatggag
acacttcccgagaggacaaaagcgtcaggcgaggccacactgaagaagacagactcgtgt
gacagtggcatcaccaagagcgacttgcgcctggacaacgtgggtgaggccaggagtccc
caggatcggagtcccatcctggcagaggtcaagcattcgttctaccccatccctgagcag
acgctgcaggccacagtcctggaggtgaggcacgagctgaaggaggacatcaaggcctta
aacgccaaaatgaccaatattgagaaacagctctctgagatactcaggatattaacttcc
agaagatcctctcagtctcctcaggagttgtttgaaatatcgaggccacagtccccagaa
tcagagagagacatttttggagccagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (26)   
   RefSeq(nuc) (8)   
   GenBank (9)   
   EMBL (9)   
3D Structure (1)   
   PDB (1)   
Protein domain (9)   
   Pfam (9)   
All databases (73)   

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