KEGG   Homo sapiens (human): 3817
Entry
3817              CDS       T01001                                 
Symbol
KLK2, KLK2A2, hGK-1, hK2
Name
(RefSeq) kallikrein related peptidase 2
  KO
K01325  tissue kallikrein [EC:3.4.21.35]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04614  Renin-angiotensin system
hsa04961  Endocrine and other factor-regulated calcium reabsorption
Drug target
Gabexate (DG01400): D01672<JP> D08004
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04614 Renin-angiotensin system
    3817 (KLK2)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    3817 (KLK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    3817 (KLK2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3817 (KLK2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.35  tissue kallikrein
     3817 (KLK2)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   3817 (KLK2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   3817 (KLK2)
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986
Other DBs
NCBI-GeneID: 3817
NCBI-ProteinID: NP_005542
OMIM: 147960
HGNC: 6363
Ensembl: ENSG00000167751
UniProt: P20151 A0A024R4J4 B4DU77
Structure
Position
19:50873439..50880567
AA seq 261 aa
MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV
LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD
LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS
NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP
AVYTKVVHYRKWIKDTIAANP
NT seq 786 nt   +upstreamnt  +downstreamnt
atgtgggacctggttctctccatcgccttgtctgtggggtgcactggtgccgtgcccctc
atccagtctcggattgtgggaggctgggagtgtgagaagcattcccaaccctggcaggtg
gctgtgtacagtcatggatgggcacactgtgggggtgtcctggtgcacccccagtgggtg
ctcacagctgcccattgcctaaagaagaatagccaggtctggctgggtcggcacaacctg
tttgagcctgaagacacaggccagagggtccctgtcagccacagcttcccacacccgctc
tacaatatgagccttctgaagcatcaaagccttagaccagatgaagactccagccatgac
ctcatgctgctccgcctgtcagagcctgccaagatcacagatgttgtgaaggtcctgggc
ctgcccacccaggagccagcactggggaccacctgctacgcctcaggctggggcagcatc
gaaccagaggagttcttgcgccccaggagtcttcagtgtgtgagcctccatctcctgtcc
aatgacatgtgtgctagagcttactctgagaaggtgacagagttcatgttgtgtgctggg
ctctggacaggtggtaaagacacttgtgggggtgattctgggggtccacttgtctgtaat
ggtgtgcttcaaggtatcacatcatggggccctgagccatgtgccctgcctgaaaagcct
gctgtgtacaccaaggtggtgcattaccggaagtggatcaaggacaccatcgcagccaac
ccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (7)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (66)   
   RefSeq(nuc) (6)   
   GenBank (30)   
   EMBL (30)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   Pfam (3)   
All databases (110)   

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